Today I'm speaking with Danny Grannick from Bristle Health on the Longevity Optimization Podcast. In this conversation, we delve into the significance of oral microbiome testing and its implications for dental health and overall well-being. Danny shares insights into the differences between good and bad bacteria, highlighting the connection between oral health and systemic diseases. We also discuss the barriers to mainstream acceptance of oral microbiome testing and the importance of raising awareness about its benefits.

Danny Grannick is a passionate advocate for oral health and the role of the microbiome in overall wellness. Throughout our discussion, we explore gender differences in oral microbiome health, the role of nitric oxide, and how these factors can influence health outcomes. The conversation emphasizes the need for a deeper understanding of the oral microbiome and its impact on systemic health, providing listeners with valuable insights into how oral health can affect their overall well-being..

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Timestamps

00:00 Introduction to Oral Microbiome Testing

03:05 The Importance of the Oral Microbiome

05:55 Understanding Good and Bad Bacteria

08:59 The Connection Between Oral Health and Systemic Diseases

11:53 Barriers to Mainstream Oral Microbiome Testing

15:10 Gender Differences in Oral Microbiome

17:56 Nitric Oxide and Oral Health

20:56 Probiotics and Oral Health

23:51 Oral Hygiene Practices and Recommendations

27:00 The Role of Mouthwash and Toothpaste

30:02 Conclusion and Future Directions

Today I'm speaking with Dr. Stephanie Venn-Watson on the Longevity Optimization Podcast. In this episode, we discuss the intriguing concept of longevity molecules, with a particular focus on C15 fatty acid and its implications for health and aging. Our conversation explores various longevity molecules, their mechanisms, and the surprising findings from research on dolphins that led to the discovery of C15 as a key factor in healthy aging. We emphasize the importance of understanding dietary sources of C15 and its role in promoting longevity and overall health.

Dr. Stephanie Venn-Watson is a leading researcher in the field of longevity and nutrition, dedicated to uncovering the connections between dietary components and health outcomes. Throughout our discussion, we delve into the significance of C15 fatty acid in relation to aging, health, and nutrition. We highlight how C15 influences biological age, cell stability, and the implications of iron overload. The conversation also explores the multifaceted benefits of C15, particularly for women's health and infant nutrition, while emphasizing the importance of optimizing C15 levels for overall well-being. Additionally, we draw parallels between the longevity of dolphins and human health, introducing emerging research on C15's role in mental health, providing listeners with valuable insights into this promising area of study.

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Timestamps

00:00 Introduction to Longevity and Health

02:48 Understanding Longevity Molecules

05:54 Mechanisms of Longevity Molecules

08:55 Research on Dolphins and Aging

12:06 The Discovery of C15 Fatty Acid

14:53 C15 vs Omega-3 Fatty Acids

18:02 C15's Role in Longevity

20:53 C15 Levels and Health Outcomes

23:58 C15 in Diet and Lifestyle

28:30 The Role of C15 in Aging and Cell Stability

31:24 Understanding Iron Overload and Its Health Implications

34:38 C15: A Multifaceted Molecule for Health

37:15 C15 and Its Impact on Women's Health

40:04 The Importance of C15 in Infant Nutrition

42:01 Optimizing C15 Levels for Better Health

44:42 Lessons from Dolphins: Longevity and Health

52:27 Emerging Research on C15 and Mental Health

Today I'm speaking with Robin Berzin, MD, on the Longevity Optimization Podcast. In this conversation, we delve into the principles of functional medicine, emphasizing its focus on treating the root causes of health issues rather than just symptoms. We discuss the importance of preventive care, particularly for women, and the need for comprehensive testing to understand metabolic health, blood sugar levels, and hormonal balance. Our conversation highlights the significance of dietary interventions, lifestyle changes, and the crucial role of sleep in overall health.

Dr. Robin Berzin is a leading advocate for functional medicine, dedicated to transforming healthcare by addressing the underlying causes of disease. Throughout our discussion, we explore the complexities of women's health, focusing on cholesterol management, proactive health measures, and the importance of nutrition and lifestyle in preventing chronic diseases. We emphasize the significance of personalized medicine and the need for women to take charge of their health through regular testing and informed dietary choices. The conversation underscores the role of foundational health practices, such as nutrition, movement, and sleep, in optimizing health outcomes and longevity, offering listeners practical advice for enhancing their well-being.

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Chapters

00:00 Introduction to Functional Medicine

03:01 The Shift from Conventional to Functional Medicine

05:54 The Importance of Preventive Care

08:58 Understanding Blood Sugar and Insulin Resistance

12:11 Comprehensive Testing for Women's Health

15:03 Dietary Interventions and Lifestyle Changes

18:06 The Role of Sleep in Health

20:56 Cardiovascular Health and Women's Wellness

24:11 Navigating Hormonal Health

26:59 The Importance of Nutrient Levels

30:12 The Future of Functional Medicine

40:39 Understanding Cholesterol and Cardiac Risk Factors

42:38 Proactive Health Measures and Heart Scans

44:48 The Importance of Baseline Testing for Women

46:58 Bridging the Gap: Women's Health and Chronic Diseases

49:46 The Role of Nutrition in Preventing Chronic Illness

52:05 The Impact of Lifestyle on Health Outcomes

55:14 Foundations of Health: Nutrition, Movement, and Sleep

58:33 Personalized Approaches to Cholesterol Management

01:01:50 Key Recommendations for Women's Health

01:16:14 Final Thoughts on Health Optimization

Today I'm speaking with Whitney Tingle, the founder of Sakara Life, on the Longevity Optimization Podcast. In this engaging conversation, we explore the realms of wellness, nutrition, and the journey of creating Sakara, a healthy meal delivery service. Whitney shares her personal health struggles and emphasizes the importance of gut health, discussing how nutrition profoundly impacts overall well-being. Our dialogue delves into the science behind food, the significance of hydration, and the challenges of sourcing quality ingredients, all while reflecting on the unique health landscape of New York City.

Whitney Tingle is a passionate advocate for holistic health and nutrition, dedicated to transforming the way people approach their diets. Throughout our discussion, we focus on various aspects of health and wellness, including dietary choices, diabetes management, and the importance of personalized medicine. We examine the impact of specific foods on health, particularly in relation to diabetes, and explore the significance of understanding individual health histories. The conversation highlights the role of gut health in overall wellness, the necessity of assessing toxic burdens, and the power of nutrition as a form of medicine. Finally, Whitney shares insights into daily wellness routines and practices that contribute to a healthier lifestyle, offering practical advice for listeners looking to enhance their well-being.

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Timestamps

00:00 Introduction to Wellness and Nutrition Conversations

03:04 The Birth of Saqqara: A Journey into Healthy Meal Delivery

05:59 Personal Health Struggles and the Gut-Skin Connection

08:45 Exploring Nutrition: The Science Behind Food and Health

11:45 The Importance of Gut Health in Skin Issues

14:54 The Role of Inflammation in Aging and Health

17:53 The Evolution of Health Understanding and Practices

20:56 Hydration and Nutrition: The Foundation of Health

24:10 Diversity in Diet: The Key to Optimal Nutrition

27:01 Sourcing Ingredients: The Challenges of Healthy Meal Prep

29:54 The New York Experience: Health and Convenience in Urban Living

37:48 Navigating Dietary Choices and Health Impacts

41:04 Understanding Diabetes Management and Dietary Approaches

44:38 The Importance of Personalized Medicine

46:50 Exploring Gut Health and Testing

52:03 Assessing Total Toxic Burden

56:10 The Role of Nutrition in Wellness

01:01:10 Daily Wellness Routines and Practices

Today I'm speaking with Liz Parrish, the founder and CEO of BioViva, on the Longevity Optimization Podcast. In this episode, we explore groundbreaking advancements in gene therapy and its potential to cure age-related diseases. Liz shares her personal journey that led to the creation of BioViva, providing insights into the mechanisms of gene therapy and the current landscape of approved therapies. Our conversation delves into the hallmarks of aging, the role of specific genes like follistatin and telomerase, and the future of gene therapy as a preventative measure for health optimization.

Liz Parrish is a pioneering figure in the field of gene therapy, dedicated to advancing the science of longevity and health optimization. Throughout our discussion, she addresses the ethical considerations surrounding gene editing and the implications for future generations. We also discuss the significance of gene therapy in combating aging, the role of telomeres in longevity, and the misconceptions about telomerase and cancer. Additionally, Liz explores the potential benefits of hyperbaric oxygen therapy and shares her personal experiences with gene therapy. The conversation touches on skincare, the philosophy of longevity, and the empowerment of women through advancements in gene therapy, highlighting the transformative potential of these innovations for future health.

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Timestamps

00:00 Introduction to Gene Therapy and Longevity

03:10 The Birth of BioViva and Personal Motivation

06:05 Advancements in Gene Therapy and Regenerative Medicine

08:49 Understanding Gene Therapy: Mechanisms and Applications

11:56 Current Approved Gene Therapies and Their Impact

15:08 Exploring the Hallmarks of Aging

17:54 The Role of Folistatin and Telomerase in Aging

21:04 Preventative Medicine and Gene Therapy

24:02 Future of Gene Therapy and Embryo Editing

27:08 The Ethics of Gene Editing and Parental Choices

29:54 Preparing for a Multi-Planetary Future

39:40 Exploring the Future of Space Travel

40:08 The Importance of Safe Space Habitation

41:06 Gene Therapy and Aging: A Deeper Dive

42:52 Telomeres and Their Role in Longevity

46:00 Cancer and Telomerase: Debunking Myths

47:55 Hyperbaric Oxygen Therapy: Potential Benefits

51:11 Balancing Regeneration and Cellular Division

53:26 Pioneering Gene Therapy: A Personal Journey

58:27 Measuring the Impact of Gene Therapy

01:03:11 Skincare and Longevity: A Personal Approach

01:10:24 Philosophy of Longevity: Balancing Life and Health

01:14:05 Empowerment Through Gene Therapy for Women

Today I'm speaking with Dr. Kay Linker on the Longevity Optimization Podcast. In this episode, we delve into the intricate relationship between neuroscience, nutrition, and longevity. Together, we explore the differences between male and female brains, the importance of brain health, and how diet and exercise play crucial roles in cognitive function. The conversation highlights the impact of neurotoxins, the significance of the blood-brain barrier, and the vital connection between gut health and brain function. We also discuss the detrimental effects of alcohol on the brain and the benefits of walking for cognitive performance.

Dr. Kay Linker is a leading expert in neuroscience and nutrition, dedicated to understanding how lifestyle choices influence brain health and longevity. Throughout our discussion, we cover various aspects of health and fitness, emphasizing the importance of cardio and strength training, the benefits of morning sun exposure, and the significant impact of sauna use on brain health. Dr. Linker introduces emerging therapies like photobiomodulation and hyperbaric oxygen therapy, while also addressing the reevaluation of Alzheimer's research and the importance of holistic approaches to brain health. Additionally, she shares insights on supplements like spermidine and rapamycin, underscoring the need for a comprehensive approach to health that integrates lifestyle choices and dietary considerations.

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Timestamps

00:00 Introduction to Longevity and Neuroscience

01:46 Understanding Brain Differences: Male vs Female

04:33 Brain Health Basics: Nutrition and Exercise

10:26 The Impact of Diet on Longevity and Brain Health

15:54 Neurotoxins and Their Effects on Brain Health

20:23 The Blood-Brain Barrier: Function and Importance

23:58 Gut Health and Its Connection to Brain Function

28:09 The Role of Alcohol in Brain Health

30:01 Exercise and Cognitive Performance

30:59 The Importance of Morning Sun for Health

34:12 Sauna Benefits: A Game Changer for Brain Health

38:43 Exploring Photobiomodulation and Brain Health

40:09 Reevaluating Alzheimer's Research and Its Implications

44:31 Emerging Therapies: Hyperbaric Oxygen and Brain Health

46:48 Nourishing the Brain: Supplements and Lifestyle Choices

Today I'm speaking with Dr. Sasha Hakman, a fertility expert, on the Longevity Optimization Podcast. In this episode, we discuss the rising trends in infertility, the impact of environmental toxins, and the critical importance of lifestyle factors such as nutrition and exercise on fertility. Dr. Hakman shares insights into the role of hormones, particularly progesterone, and how thyroid and autoimmune conditions can affect fertility outcomes. The conversation emphasizes the need for awareness and proactive measures to optimize fertility.

Dr. Sasha Hakman is a renowned fertility specialist dedicated to helping individuals and couples navigate the complexities of reproductive health. Throughout our discussion, we explore the intricate relationship between thyroid health, nutrient deficiencies, and fertility, highlighting the importance of maintaining optimal TSH levels for women trying to conceive. We also delve into the role of various nutrients, particularly vitamin D, in enhancing fertility. The conversation covers the impact of alcohol on reproductive health, the aging of eggs, and how lifestyle changes can significantly improve fertility outcomes. Personal experiences in fertility treatments underscore the importance of individualized care and the need for supportive healthcare providers. Additionally, we discuss various aspects of fertility, including the impact of age on conception, the process and considerations of egg freezing, and the management of conditions like endometriosis and PCOS. The complexities of IVF, including success rates and challenges associated with egg retrieval and embryo transfer, are also addressed, emphasizing the importance of understanding one’s reproductive health and the implications of lifestyle choices on fertility outcomes.

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Timestamps

00:00 Introduction to Fertility and Infertility Trends

02:51 The Impact of Environmental Toxins on Fertility

06:08 Lifestyle Factors Affecting Fertility

11:48 The Role of Exercise and Nutrition in Fertility

17:51 Understanding Hormones: The Role of Progesterone

23:56 Thyroid and Autoimmune Conditions in Fertility

37:05 Understanding Thyroid Health and Fertility

41:39 The Role of Nutrients in Fertility

51:42 Alcohol and Its Impact on Fertility

55:56 Egg Quality and Aging: What You Need to Know

01:09:08 Personal Experiences in Fertility Treatments

01:13:25 Understanding Age and Fertility

01:20:04 The Journey of Egg Freezing

01:30:35 Navigating Fertility in Your 30s

01:39:01 Managing Endometriosis and PCOS

01:46:51 The Complexities of IVF and Egg Retrieval

Today I'm speaking with @HarperCarrollAI  an AI and ML software engineer, on the Longevity Optimization Podcast. In this episode, we explore the fascinating intersection of artificial intelligence and health optimization. Harper shares insights into the concept of AI as the ultimate polymath, detailing her journey into the field and the transformative potential of AI in revolutionizing health diagnostics and treatments, particularly in cancer care. The conversation delves into the implications of AI in personalized medicine and how technology can shape the future of health optimization.Harper Carroll is an AI/ML engineer, advisor and educator focused on making AI concepts accessible. With almost a decade of formal experience in AI, she holds two Computer Science degrees from Stanford University specializing in AI, worked at Facebook/Meta on News Feed Ranking, Integrity Intelligence, and AR, and then was Founding Engineer and then Head of AI/ML at a startup acquired by NVIDIA. Her background combines technical expertise with teaching experience, including as a TA for advanced CS and AI courses at Stanford, including a PhD-level core AI course. Her model fine-tuning guides became the most popular fine-tuning guides on Google. In just one (1) year of teaching AI online, she has garnered 0.5M followers.Polymath book Harper references: Genesis: Artificial Intelligence, Hope, and the Human Spirit: https://www.amazon.com/Genesis-Artificial-Intelligence-Human-Spirit/dp/0316581291Follow Harper on IG: https://www.instagram.com/harpercarrollai/Follow Her on YouTube: https://www.youtube.com/@HarperCarrollAIFollow Her on X: https://x.com/HarperSCarrollVisit Her Website: https://www.harpercarrollai.comTimestamps00:00 Introduction to AI and Longevity05:08 The Polymath Concept in AI09:58 Harper's Journey into AI14:47 Understanding AI: Definitions and Applications19:56 AI in Health: Opportunities and Concerns25:00 AI's Role in Cancer Treatment and Diagnostics30:10 Future of AI in Personalized Medicine32:23 Innovative Approaches to Women's Health35:11 The Role of AI in Health Optimization36:51 Empathy and Virtual Reality Experiences41:05 AI's Impact on Creativity and Accessibility43:59 AI as a Personal Assistant in Daily Life48:54 Understanding AI Hallucinations and Their Implications53:28 The Environmental Impact of AI and Future Solutions

Today I'm speaking with Julian Mitchell from Life Cykel. In this episode, we delve into the fascinating world of functional mushrooms, particularly focusing on Lion's Mane, Reishi, and Cordyceps. Julian shares insights into the origins of Life Cykel and the extensive research supporting the benefits of these mushrooms for cognitive health, sleep optimization, and gut health. The conversation emphasizes the importance of biohacking and how mushrooms can enhance overall well-being and longevity.

Julian Mitchell is a passionate advocate for the health benefits of functional mushrooms and the co-founder of Life Cykel, a company dedicated to harnessing the power of these natural wonders. With a background in health and wellness, Julian has dedicated his career to exploring the intersection of traditional medicine and modern science. He highlights the significance of gut health and its profound impact on overall well-being, discussing the roles of mushrooms like Turkey Tail and Shiitake in promoting health. The conversation also covers the importance of gut testing, the historical use of mushrooms in traditional medicine, and advancements in extraction methods that improve bioavailability. Julian emphasizes sustainable cultivation practices and rigorous quality control measures to ensure product integrity, concluding with a focus on the benefits of specific mushrooms and the importance of choosing high-quality products for optimal health.

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Timestamps

00:00 Introduction to Functional Mushrooms and Life Cykel

01:30 The Journey of Starting a Mushroom Company

04:08 Research and Benefits of Lion's Mane Mushroom

09:02 Lion's Mane and Its Impact on Sleep and Memory

10:40 Exploring Other Mushrooms: Reishi and Cordyceps

19:35 The Role of Turkey Tail and Gut Health

28:04 The Importance of Gut Health

29:19 Understanding Gut Testing and Probiotics

30:21 Root Causes of Health Issues

31:44 Exploring Turkey Tail Mushroom

33:07 Historical Use of Mushrooms in Medicine

35:26 Advancements in Mushroom Extraction

39:03 Sustainable Mushroom Cultivation

42:00 Quality Control in Mushroom Products

51:34 Benefits of Shiitake Mushroom

55:29 Bioavailability of Mushroom Products

59:22 Choosing Quality Mushroom Products

Today I'm speaking with Dr. Paziotopoulos on the Longevity Optimization Podcast. In this episode, we explore his unique journey into the field of medicine and longevity, focusing on the integration of AI in health monitoring and the innovative concept of medical maintenance engineering. The conversation delves into the importance of imaging, the role of supplements, and the critical significance of compliance in health programs. Dr. Paziotopoulos highlights key compounds for longevity, emphasizing the essential role of vitamin D in overall health and its importance in cancer prevention.

Dr. Paziotopoulos is a distinguished physician and researcher with a deep commitment to advancing the field of longevity and personalized medicine. With a background in both traditional medicine and cutting-edge technology, he has become a thought leader in the integration of artificial intelligence into health monitoring systems. His expertise encompasses a wide range of health topics, including the development of innovative health protocols and the exploration of novel compounds that promote longevity. Dr. Paziotopoulos is particularly passionate about the role of vitamin D in health, as well as the importance of water filtration and gut health. His forward-thinking approach emphasizes the need for data-driven solutions in healthcare, making him a pivotal figure in the future of age-reversal medicine and functional health.

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Timestamps

02:57 The Journey to Medicine and Longevity

06:11 Medical Maintenance Engineering: A New Approach

09:05 Imaging and AI in Health Monitoring

11:59 The Role of Supplements in Longevity

18:03 The Importance of Compliance in Health Programs

21:01 Exploring Key Compounds for Longevity

23:59 The Benefits of Natural Foods vs. Supplements

26:57 Vitamin D: The Essential Hormone for Health

31:04 Vitamin D and Cancer Prevention

32:41 Exploring Methylene Blue

34:32 The Importance of Water Filtration

40:53 Patient Management and Protocol Development

52:33 Age-Reversal Medicine and Future Therapies

01:01:04 The Future of Medical Maintenance Engineering

01:03:43 The Future of Data-Driven Medicine

01:12:27 Understanding Omics and Personalized Health

01:19:24 AI's Role in Longevity and Health Optimization

01:26:40 Innovations in Cancer Detection and Treatment