In the 2013 video game The Last of Us and its 2023 TV adaptation, humanity is overrun by a mutant parasitic fungus called Cordyceps, which disfigures its victims and takes over their minds, turning them into violent, unthinking walking mushrooms called clickers. But this horrifying premise is hardly unique; indeed, the motif of infection and assimilation by an alien parasite crops up time and time again in popular fiction, from the 1950s novels The Puppet Masters and The Body Snatchers by Robert Heinlein and Jack Finney and their numerous screen adaptations to the 1998 film The Faculty and classic episodes of The X-Files, Star Trek: the Next Generation, The Outer Limits, and Futurama. And no wonder: horror fiction often reflects universal anxieties, and parasites have been an unwelcome part of the human experience since the dawn of time. From the tapeworms and hookworms that infect our guts to the filarial worms that cause elephantiasis to the single-celled protozoa that cause malaria, sleeping sickness, river blindness and other horrible diseases, these biological infiltrators have been - and still are - responsible for a great deal of human suffering the world over. And while the mind-hijacking parasites of popular fiction may seem like gross exaggerations created for the sake of chills and thrills, this is not the case, for such creatures are horrifyingly real. For example, Cordyceps from The Last of Us is based on an actual parasitic fungus of the same name that infects ants and other small insects, hijacking their minds and bodies and turning them into mindless slaves with one single purpose: to spread their new master’s spores far and wide. Indeed, such devious puppet masters are remarkably common in the natural world, being found in nearly every habitat and family of life - including our very own bodies. This is the story of the real-life zombie makers, the most horrifying - and fascinating - creatures on earth.

Author: Gilles Messier

Host: Simon Whistler

Editor: Daven Hiskey

Producer: Samuel Avila

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