The Poison Lab

By Clinical Toxicology LLC

Dive into the captivating world of poisons with The Poison Lab! Hosted by Clinical Toxicologist Ryan Feldman (@EMPoisonPharmD), who has over a decade of managing poisoning and drug overdose via poison... more

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FAQs about The Poison Lab:

How many episodes does The Poison Lab have?

The podcast currently has 76 episodes available.

The Poison Lab episodes:

March 02, 2022Toxicologists vs the Internet (#5) With Guest Dr Howard Greller MD (Sirius XM Doctor Radio Emergency Medicine Show, Dantastic Mr Tox & Howard, Tox & Hound)
Dr. Howard Greller, MD (Sirius XM Doctor Radio Emergency Medicine Show, Dantastic Mr Tox & Howard, Tox & Hound) joins the show. A FANTASTIC episode complete with toxic sleuthing of fatal poisoning cases and answering questions from reddit.com/r/askdrugs.
Music from Pixabay
Additional information on toxins from fatal poisoning cases
Toxin 1
Toxin 2
Toxin 3
Toxin 4
Popper article referenced by Dr. Greller

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Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
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Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
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...more
1h 27min
February 02, 2022Where is Episode 13 ? Bonus Episodes AND Next Episode Guest Dr. Howard Greller MD (Sirius XM Doctor Radio Emergency Medicine Show, Dantastic Mr Tox & Howard, Tox & Hound),
No episode today. Head here for the live radio show!
Join us next show for Dr. Howard Greller of Sirius XM Doctor Radio, Dantastic Mr Tox & Howard, and Tox & Hound
Find the article about the poison lab here
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
15min
December 08, 2021Lethal Buttock Injection (And Other Toxicities of Illegal Cosmetic Body Fillers)
In this episode Ryan and Toxo dissect the fascinating underbelly of illegal cosmetic procedures and breakdown the toxicities that arise from them.
Intro
Case report of hemolysis after sodium deoxycholate injection
History

Epidemiology
ASPS stats
Florida Unlicensed Activity Unit
Cost of surgeon fee for buttock implant 2018

Recent new stories
Botox and Bubbles grifter
Quick bio on cases mentioned in show

Common injection practices
Feminizing body contouring (pumping parties)
Synthol muscles
Capsule face cosmetics

Toxicity
Infection
Self explanatory

Filler embolism
Review 1, Review 2, Review 3
Filler lodges in pulmonary vasculature->clotting, bleeding, inflammation
95% occur within 72 hours
Primarily respiratory symptoms (cough/hypoxemia)
Chest x ray ground glass opacity
Treat with supportive care (oxygen all the way through ECMO) +/- steroids
Filler Blindness
CRAO from body filler
No effective treatment (exception, can use hyaluronidase if filler is hyaluronic acid)

Granuloma
Inflammatory nodules from prolonged filler exposure
May occur months to year after injection
Illegal cosmetic= frequently lipogranuloma due to oil being present in many illegal cosmetic
Granulomatous hypercalcemia
Excess calcitriol production from ganuloma causes hyperCA
Can be extremely delayed (up to 28 years)
Recurrence up to 45%
Treat with standard therapies (fluid, bisphosphonate) + steroids and/or ketoconazole to turn down granuloma CYP27B1 calcitriol production

Case from the show
Some details changed for educational purposes

Music in this episode from pixabay.com
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
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Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
1h 1min
October 06, 2021A Mysterious Case of Hypercalcemia and Subdermal Nodules in a Transgender Patient (Episode #12 Mystery Case)
Send in your guesses to [email protected]
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
2min
October 06, 2021Toxicologists vs the Internet (#4) With Guest Dr Andrew Farkas MD
In this episode of toxicologist vs internet guest Dr. Andrew Farkas, MD joins the show. This a great episode that covers everything from the drugs you would need in the apocalypse to what to worry about if your cats are dying. Complete with toxic sleuthing of fatal poisoning cases and answering questions from reddit.com/r/askdrugs.
Research from Dr Farkas
Additional information on toxins from Fatal poisoning cases
Toxin 1
Toxin 2
Toxin 3
Toxin 4
"Toxicologist vs the internet" segment
Cocaethylene review
Benzodiazepine urine drug screening - Blog post

Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
1h 9min
August 04, 2021You Left Your Bladder in The K-Hole?
In this episode Ryan and Toxo take a closer look at ketamine induced irreversible bladder damage.
History
Discovery of Ketamine
Melamine outbreaks

Clinical Effects
Index cases
Survey of Ketamine use prior to symptoms

Mechanism/Treatment
Mechanism/Treatment systematic review
Rat models

Support the show
Review the show where ever your listening
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Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
33min
June 02, 2021A Mysterious Case of Bloody and Painful Urination in a 24 Year Old Male (Episode #10 Mystery Case)
What substance could cause these symptoms? Send your guesses to [email protected] to participate in episode 10!
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
2min
June 02, 2021Toxicologists vs the Internet (#3) With Guest Dr Justin Corcoran MD
In this episode of toxicologist vs the internet Ryan Is joined by special guest Dr. Justin Corcoran, MD an emergency medicine physician and medical toxicologist. They take turns answering questions from reddit.com/r/askdrugs (the internet, really, really needs a toxicologist) and challenge each others toxic sleuthing by presenting cases of poisoning and allowing the other to determine the toxin responsible.
"Toxicologist vs the internet" segment
Everythingisosm.com (Blog post)
Biased Mu Receptor ligands
Oliceridine mouse studies
Opioid hearing loss (Blog post)
Opioid hearing loss review
Tox pupils (Blog post)
Why tramadol is awful (Blog post)

Additional information on toxins from Fatal poisoning cases
Toxin 1
Toxin 2
Toxin 3
Toxin 4

Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
1h 12min
April 19, 2021Mini Episode: Setting The Record Straight on Delta 8 (THC)
Ryan and Toxo dive in to Delta 8 THC, a new (maybe?) legal drug sweeping the U.S.
Delta-8 THC: Key Resources and StudiesNew York Times Coverage
Comprehensive article on Delta-8 THC, its growing popularity, and concerns: https://www.nytimes.com/2021/02/27/health/marijuana-hemp-delta-8-thc.html

Studies of Delta-8 THC in Humans
Systematic Review:
Summarizes findings from a single key study on Delta-8 THC. https://pubmed.ncbi.nlm.nih.gov/29385080/
Original Study (may not be accessible):
Investigates Delta-8 THC effects in humans.
https://www.karger.com/Article/Abstract/136375

Testing Strategies for Delta-8 THC
HPLC-MS/MS Strategies:
Analytical methods for testing Delta-8 THC.
https://academic.oup.com/jat/advance-article-abstract/doi/10.1093/jat/bkaa184/6018445?redirectedFrom=fulltext

Cannabinoid Receptor Binding
Mechanism of Action:
Study exploring how Delta-8 THC binds to cannabinoid receptors.
https://pubmed.ncbi.nlm.nih.gov/27398024/

If you’re interested in learning more or exploring the impact of Delta-8 THC, these resources provide a great starting point. Thank you for listening!
Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
27min
March 31, 2021More Bitter than Sweet (Mad Honey and Grayanotoxin)
Case from the show
https://pubmed.ncbi.nlm.nih.gov/22163140/

Mithradates
https://www.wemjournal.org/article/S1080-6032(11)00043-3/pdf

Case series on mad honey effects
https://pubmed.ncbi.nlm.nih.gov/20575670/

Blog post on sodium channel openers
https://emcrit.org/toxhound/ff-plant-sodium-channel-openers/

Support the show
Review the show where ever your listening
Get Messages from Toxo (Join the Newsletter!)
Join as a supporting member
Ad free episodes
Bonus content and early access
Discounts and give aways on GOTA PICCEM Mushroom card game

The GOTTA PICCEM Poisonous Mushroom Game!
The Poisonus Fungus Amongus Children's Book!
Full book reading (6 minutes!)

Tox trinkets (Rep the show at home!)
Reach the show
Email: [email protected]

More Show Resources
Ryan's Medical Games and Resources
Show Website
...more
43min

FAQs about The Poison Lab:

How many episodes does The Poison Lab have?

The podcast currently has 76 episodes available.

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