Psychoactive plants are at the heart of many traditional and Indigenous spiritual and religious traditions, yet many have been outlawed or severely restricted. How does society determine religious freedom? With: Jeremy Narby on Amazonian shamanic knowledge; and Jeffrey Bronfman, the U.S. legal and spiritual representative of Brazil's União do Vegetal (UDV) church, whose legal victories for its U.S. domestic use of ayahuasca have taken it to the Supreme Court; moderated by Bioneers' J.P. Harpignies.