The Cardinals lost for the fourth straight game, this time to the Indianapolis Colts. Jacoby Brissett started for the Cardinals at quarterback and played well. The offense played better than it had previously, but the defense failed again. Jess and Seth talk about Brissett's play, the offense, the defense and whether there is or should be a quarterback controversy.

Following the Cardinals' embarrassing meltdown in Week 5 against the Tennessee Titans, they now face the 4-1 Indianapolis Colts on the road. Jess and Seth preview the game, look at the play of Daniel Jones, talk about keys to victory and important matchups, and they give you their picks, predictions and best bets for the game.

The Cardinals lost to the Titans and had a clown show of a second half. Between a snap to Kyler Murray's facemask, a touchdown turned turnover, a takeaway turned touchdown and a sideline incident with Jonathan Gannon, Jess and Seth have a lot to talk about.

Jess and Seth preview Cardinals-Titans in this show. They talk about the Titans' season so far, what the Cardinals need to do to beat the Titans, what matchups we will pay attention to and then give our predictions and favorite prop bets for the game.

Titans Wire writer Mark Mihalko, who joined Jess in the offseason opponent preview show about Tennessee, joined him again to talk about the Cardinals' Week 5 matchup with the Titans. They talk about the Titans' season, keys to the matchup this week and make predictions.

The Cardinals had struggles offensively in Week 4 and lost 23-20 to the Seahawks on Thursday night on a last-second field goal. Jess and Seth talk about it.

The Cardinals and Seahawks play Thursday night. Seahawks Wire managing editor Kole Musgrove joined Jess on the show to give Cardinals fans an inside perspective to Arizona's Week 4 opponent. They talk about Seattle's start to the season, keys and matchups to watch in the game and give predictions.

The Cardinals play the Seahawks at home Thursday night and can make everyone forget about what happened against the 49ers. It will be a tough game. Jess and Seth preview the game. They go over what the Seahawks have done so far this season, look at the keys and matchups to watch, and they make their predictions for the game. They also give you some prop bets to consider.

With the Cardinals' 16-15 last-second loss to the 49ers in Week 3, Jess and Seth react to the play on offense and defense, looking at both the good and the bad they saw, and they talk about the impact of the season-ending injury to James Conner.

With the Cardinals and 49ers playing Sunday in Week 3, Jess brings on Niners Nation's Kyle Posey to preview the game. Posey tells us about the 49ers' first two games, gives us important matchups and makes predictions.