Dr. Valentina Greco is the Carolyn Slayman Professor of Genetics at Yale University. Her lab has developed novel live imaging approaches to track and manipulate stem cells in live animals, allowing them to study the complex orchestration of tissue regeneration using the skin as a model system.

Dr. Madeline Lancaster is a Group Leader at the MRC Laboratory of Molecular Biology in Cambridge, UK. The Lancaster lab has developed cerebral organoids as a model system to better understand human brain evolution, development, and neurodevelopmental disorders. She joined us to discuss her research presentated at the ISSCR 2020 conference.

Dr. Benoit Bruneau is the Director of the Gladstone Institute of Cardiovascular Disease. His lab uses mouse models and human iPSCs to investigate the transcription factor networks that regulate sets of genes critical for heart development.

Dr. Karl Koehler is an Assistant Professor of Otolaryngology at Harvard Medical School. His lab focuses on using human organoid systems as a platform to model congenital diseases and develop regenerative medicine therapies for the inner ear and various craniofacial tissues.

Dr. Freda Miller, from the Hospital for Sick Children Research Institute and the University of Toronto, studies the cellular mechanisms that regulate development of the mammalian nervous system, with a particular interest in stem cells and trophic factors.

Dr. Hans Clevers from the Hubrecht Institute for Developmental Biology and Stem Cell Research is a pioneer in the field, studying the molecular mechanisms of tissue development and cancer of various organs using organoids made from adult Lgr5 stem cells.

Dr. Sheila Chari is the Editor-in-Chief at the journal Cell Stem Cell, and Executive Editor at Cell Press. As the Editor-in-Chief, Dr. Chari’s primary responsibilities are knowing and publishing the top stem cell discoveries, driving journal publishing strategy, and managing a global editorial staff.

Dr. Josef Penninger is from the University of British Columbia and the Institute for Molecular Biotechnology of the Austrian Academy of Sciences in Vienna, Austria. He was previously on the podcast to talk about his research developing human blood vessel organoids. Dr. Penninger’s team has identified a trial drug that can significantly block early stages of COVID-19 in human blood vessel and kidney organoids.

Dr. Darcy Wagner from the Lund Stem Cell Center uses a multidisciplinary approach to understand how the extracellular environment directs stem cell behavior for endogenous and exogenous lung tissue regeneration.

Dr. Deepak Srivastava is the President of the Gladstone Institutes and the International Society for Stem Cell Research, and the co-founder of Tenaya Therapeutics. His lab investigates the gene networks that guide cardiogenesis by developing models of heart disease using patient-derived iPSCs and CRISPR technology.