The Stem Cell Podcast

By The Stem Cell PodcastScience Natural Sciences

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The Stem Cell Podcast episodes

October 22, 2024 Ep. 279: “Direct Reprogramming” Featuring Dr. Samantha Morris
Dr. Samantha Morris is an Associate Professor of Medicine at Brigham and Women's Hospital and Associate Professor of Systems Biology at Harvard Medical School. She talks about dissecting and manipulating the genetic pathways that regulate cell identity. She discusses tools to measure cell fate transitions and incorporating in silico and in vitro experiments.
1 hr 28 min
October 15, 2024 Ep. 278: “Stembryo Engineering” Featuring Dr. Alfonso Martinez Arias
Dr. Alfonso Martinez Arias is the CREA Research Professor in the Department of Systems Bioengineering of the Universitat Pompeu Fabra in Barcelona. He talks about his path to developmental biology research and developing gastruloids to model human development. He also discusses standards for embryo models and his recent research on hematopoiesis.
1 hr 32 min
October 01, 2024 Ep. 277: “Lung Development” Featuring Dr. Behzad Yeganeh
Dr. Behzad Yeganeh is an Associate Scientist at the Children's Hospital of Eastern Ontario Research Institute and the University of Ottawa. His work focuses on lung development and injury. He talks about neonatal lung diseases and the mechanisms that regulate autophagy and apoptosis.
1 hr 15 min
September 17, 2024 Ep. 276: “Musculoskeletal Disorders” Featuring Dr. Dmitriy Sheyn
Dr. Dmitriy Sheyn is an Associate Professor in the Department of Orthopedics and Regenerative Medicine Institute at Cedars-Sinai Medical Center. His lab focuses on the development of stem cell therapies for multiple musculoskeletal disorders caused by acute injuries and aging. He talks about ways to model disc degeneration and tendon injuries. He also discuses his lab's work on tendon differentiation and the mechanisms of low back pain.
1 hr 38 min
September 03, 2024 Ep. 275: “Liver Organogenesis” Featuring Dr. Ludovic Vallier
Dr. Ludovic Vallier is the W3 Einstein Strategic Professor for Stem Cells in Regenerative Therapies at the Berlin Institute of Health and a Max Planck Fellow at the Max Planck Institute for Molecular Genetics. His lab uses stem cells to model embryonic development in vitro and to produce liver cells with an interest for cell therapy. He talks about modeling non-alcoholic fatty liver disease and his lab's pivot to SARS-CoV-2 research early in the pandemic. He also discusses how iPSCs could be used to regenerate the liver after injury.
1 hr 12 min
August 20, 2024 Ep. 274: “Brain Organoids” Featuring Dr. Ziyuan Guo
Dr. Ziyuan Guo is an Assistant Professor of Pediatrics at the Center for Stem Cell & Organoid Medicine at Cincinnati Children's Hospital. He talks about in vivo reprogramming and cell and gene therapy in neurodevelopmental and neurodegenerative disorders. He also discusses assembloids to model the blood-brain barrier and strategies for organoid vascularization.
1 hr 21 min
August 06, 2024 Ep. 273: “Hematopoiesis and Cancer” Featuring Dr. Irving Weissman
Dr. Irving Weissman is the Virginia and Daniel Ludwig Professor of Clinical Cancer Research and Professor of Pathology and Developmental Biology at Stanford University. Dr. Weissman was the first scientist to identify and isolate mammalian blood-forming stem cells in mice, and his work has contributed to the understanding of how a single hematopoietic stem cell can give rise to specialized blood cells. He talks about developing new treatments for metastatic breast cancer and severe combined immunodeficiency. He also discusses myeloid bias in aging and strategies for commercializing new therapies.
1 hr 52 min
July 30, 2024ISSCR 2024: On the Ground
In July 2024, we attended ISSCR 2024, the annual meeting of the International Society for Stem Cell Research, in Hamburg, Germany. We spoke with delegates about their research, their impressions of the meeting, and the most memorable research presented. They discussed their experiences in Europe and where they would like to see the meeting go next.
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Wallchart: Reporting Practices for Publishing Results with hPSCs
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44 min
July 23, 2024 Ep. 272: “Live at ISSCR 2024: Stem Cell Research in Space” Featuring Drs. Davide Marotta and Catriona Jamieson
Dr. Davide Marotta is the Program Director for In-Space Biomanufacturing at the International Space Station National Laboratory. Dr. Catriona Jamieson is the Director of the Sanford Stem Cell Institute at the University of California, San Diego. In this special episode recorded in front of a live audience at ISSCR 2024 in Hamburg, Germany, they talk about the opportunities and challenges of working with stem cells in a microgravity environment, and what this could mean for the future of stem cell-based therapies. They discuss the challenges of culturing cells in space, the need for risk reduction and collaboration, and how microgravity affects stem cell growth and aging. They also discuss the opportunities that come with the growing popularity of private spaceflight.
1 hr
July 14, 2024ISSCR 2024: Day 4
In July 2024, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Hamburg, Germany, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of four episodes from the meeting. Sessions focused on stem cell research in space, regulatory and ethical considerations for human embryo models, and developing therapies for SCID, epilepsy, and spinal cord injury. Daylon and Arun also discussed work on salivary gland organoids and patient advocacy in Parkinson’s disease research.
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27 min