In this conversation, Dr. Joanna Moncrieff discusses her book 'Chemically Imbalanced'. She argues that there is no compelling evidence for a chemical imbalance in depression and questions the continued prescription of antidepressants. We explore the interests of the pharmaceutical industry, the ethical implications of using drugs to mask symptoms, and the need for a paradigm shift in mental health treatment. We discuss the influence of the pharmaceutical industry on psychiatric literature and the defensive stance of the psychiatric profession against critical viewpoints.