TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson’s disease.

Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison

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Links for this episode

• Gut-brain alpha-synuclein transport in PD (Neuron)
• Gut has a mind of its own (Colbert Report)
• Timestamps by Jolene. Thanks!

Music is by Ronald Jenkees

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