A TWiV duo reviews how SARS-CoV-2 attacks the olfactory mucosa but spares the olfactory bulb, vaccination with BNT162b2 induces virus-specific stem cell memory T cells, and development of an oral protease inhibitor for the treatment of COVID-19. Hosts: Vincent Racaniello and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode How SARS-CoV-2 attacks olfactory mucosa (Cell) SARS-CoV-2-specific stem cell memory T cells after mRNA vaccine (Sci Immunol) Oral SARS-CoV-2 protease inhibitor (Science) Paxlovid phase 2/3 trial preliminary results (Pfizer) Letters read on TWiV 829 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Coronavirus Neutralizing Antibodies and mRNA Vaccine Video Vincent – MHC restriction of cytotoxic T cell lysis (Nobel description) Listener Picks Lisa – Shall Furnish Medicine Bistra – Saving the World by Julia Alvarez Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]