TWiV reviews the impact of vaccination on SARS-CoV-2, the latest information on Omicron, West Nile virus transmission by organ transplantation, and why a 16 week interval between doses of BNT162b2 vaccine is better than a shorter interval. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Coronavirus in the US (NY Times) Omicron variant (NY Times) West Nile virus transmission by organ transplantation (Emerg Inf Dis) Stronger antibody response after 16 week mRNA dose (Cell Host Micr) Higher antibody response with 7 week dosing (Clin Inf Dis) Immune response after recovery and 1 vaccine dose (Sci Transl Med) Booster guidance in Canada (pdf) Timestamps by Jolene. Thanks! Weekly Picks Kathy – CDC U-M flu report (lay version, MMWR) Rich – Thagomizer Alan – Descent into Darkness by Edward Raymer Vincent – Funding: Blinding peer review Listener Picks Lynne – ACE2 in chewing gum Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]