On this week’s episode of The Big Interview podcast, the philanthropist sits down with Katie to offer her insights on billionaire donors, kids on phones, and the importance of women’s healthcare.

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.

In today’s episode, Zoë is joined by WIRED’s Max Zeff to discuss five stories you need to know about this week — from the political fallout after the release of the Epstein files, to why two young mormon men created an app to help men stop "gooning". Then, we dive into Gemini 3's release and how companies like Google and OpenAI are honing in on AI profitability. 

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.

Whether it's teenagers reviving the Benadryl TikTok challenge or people signing up for an out of body experience program previously used by the CIA, some of us are chasing unconventional trips. Bad trips, essentially. But these trends are happening at a time when AI companies are also looking to create a “cleaner” trip for users, and others are using AI chatbots to therapeutically guide their psychedelic trips. Mike sits down with WIRED's Boone Ashworth and Manisha Krishnan to discuss these trends, and the promises and limitations of relying on tech to avoid bad trips.

Articles mentioned in this episode: 

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.

Right now much of the US economy rests on AI’s future. In fact, Odd Lots cohost Joe Weisenthal says the rest of the economy that isn't tech or AI related is creaking along. He breaks down for Katie why AI’s impact on finance goes beyond billion-dollar investments. 

Follow the UnCanny Valley feed for WIRED’s best and brightest as they provide an insider analysis of the overlap between tech and politics, from the influence of Silicon Valley on the Trump administration to how inaccurate information from artificial intelligence (AI) chatbots fanned the fire on social protests. 

In today’s episode, Zoë is joined by WIRED’s Brian Barrett to discuss five stories you need to know about this week — from how AI affairs can now be grounds for divorce, to why Google is suing one of the largest networks of text scammers. Then, we dive into how the Department of Homeland Security illegally gathered the data of hundreds of Chicago residents. 

Articles mentioned in this episode: 

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.

Recently, WIRED’s editor at large Steven Levy sat down for an interview with Palantir’s CEO Alex Karp. Karp defended his company’s contracts with clients like ICE and the Israeli government, which have increasingly gathered criticism. 

In today’s episode, we dive into the most revealing parts of the interview and break down how Karp’s technostate ideology has rippled across Silicon Valley.

Articles mentioned in this episode:

Follow the UnCanny Valley feed for WIRED’s best and brightest as they provide an insider analysis of the overlap between tech and politics, from the influence of Silicon Valley on the Trump administration to how inaccurate information from artificial intelligence (AI) chatbots fanned the fire on social protests. 

Steven Adler used to lead product safety at OpenAI. When Katie read his recent op-ed asking OpenAI to prove that they have and continue to address safety issues, she knew she wanted to talk to him. This week she sits down with Steven to talk about what AI users should know about their bots.

Follow the UnCanny Valley feed for WIRED’s best and brightest as they provide an insider analysis of the overlap between tech and politics, from the influence of Silicon Valley on the Trump administration to how inaccurate information from artificial intelligence (AI) chatbots fanned the fire on social protests. 

In today’s episode, Zoë is joined by WIRED’s Leah Feiger to discuss the top stories you need to know about this week — from Zuckerberg’s illegal school to the repercussions behind the recent pardoning of Changpeng Zhao, Binance’s ex-CEO. Then, Zoë and Leah discuss how fandom on the internet played a key tole in this week’s election results. 

Articles mentioned in this episode: 

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.

Chatter about an AI bubble has been everywhere lately, and top tech companies like Google, Meta, and Microsoft have doubled down on their AI investments for 2026. But how have analysts in the past accurately identified forming tech bubbles? Mike and Lauren sit down with WIRED contributor and author of the newsletter Blood in the Machine Brian Merchant to break down the four criteria some researchers have used in the past to understand and brace for the worst. 

Join WIRED’s best and brightest as they provide an insider analysis of the overlap between tech and politics, from the influence of Silicon Valley on the Trump administration to how inaccurate information from artificial intelligence (Ai) chatbots fanned the fire on social protests.

Katie catches up with fellow journalist and podcast host, Kara Swisher to talk about interviewing arrogant pricks, the power of negging and who would play her in a movie.  And she tells Katie if she had to she would rather work for Sam Altman over Mark Zuckerberg. 

Join WIRED’s best and brightest on Uncanny Valley as they dissect the collision of tech, politics, finance, and business, from Alexis Ohanian's newest tech venture to the effects of inaccurate information from artificial intelligence (AI) chatbots on social protests.