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Dr. Iris Manor on ADHD, Trauma, PTSD, and Resilience: Risks, Mechanisms, and Treatment

The host interviews Dr. Iris Manor, a child and adolescent psychiatrist and ADHD researcher, about links between ADHD and traumatic stress disorders, including a Denmark study finding children with ADHD are about 11 times more likely to develop PTSD. Manor distinguishes trauma exposure from traumatic stress disorders and describes behavioral risk (novelty-seeking, impulsivity) and shared neurobiology (hippocampus/ventromedial prefrontal networks, inflammatory cytokines), including possible transgenerational effects of maternal trauma. She argues ADHD and traumatic stress are usually separate but interacting diagnoses, and emphasizes resilience through structure, goals, and avoiding helplessness, noting ADHD makes these harder. She warns clinicians often stop stimulants after trauma despite potential benefit, recommends treating ADHD (and parents’ ADHD), and highlights emotional dysregulation requiring treatment (often guanfacine) to enable ADHD and trauma care. The discussion also covers overlap with chronic pain/fibromyalgia and long COVID, autism-related vulnerability, and disagreement with claims that ADHD is primarily caused by trauma.

00:00 Trauma and ADHD Link
03:11 Why Risk Is Higher
04:02 Biology and Inflammation
08:04 Which Comes First
09:49 Types of Trauma Examples
11:52 National Trauma Risk Groups
15:14 Covid and Chronic Pain
20:42 Resilience Rules and Structure
22:20 Treat ADHD During Trauma
26:39 Family Screening and Care
31:12 ADHD Impact on PTSD Treatment
33:33 Emotional Dysregulation Hierarchy
35:51 Guanfacine for Dysregulation
38:36 Autism Risk and

Click here for the YouTube channel

International Conference on ADHD in November 2025 where Dr. Lenz will be one of the speakers.

Joy Lenz

Fibromyalgia 101. A list of fibromyalgia podcast episodes that are great if you are new and don't know where to start. 

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When I started this podcast and YouTube Channel—and the book that came before it—I had my patients in mind. Office visits are short, but understanding complex, often misunderstood conditions like fibromyalgia takes time. That’s why I created this space: to offer education, validation, and hope. If you’ve been told fibromyalgia “isn’t real” or that it’s “all in your head,” know this—I see you. I believe you. This podcast aims to affirm your experience and explain the science behind it. Whether you live with fibromyalgia, care for someone who does, or are a healthcare professional looking to better support patients, you’ll find trusted, evidence-based insights here, drawn from my 29+ years as an MD.

Please remember to talk with your doctor about your symptoms and care. This content doesn’t replace per...