Do you feel that you matter? That among 7.7 billion people on earth, and trillions of other forces in the universe, you are indispensable and your life is vital? This is not a small or academic question;  every decision you make, every move you take, is effected by how much you value your life. If you  feel that your life doesn't matter much, then all your life choices and relationships don't matter that much either. If your life is negligible then everything you do is also negligible.