Extend Podcast with Darshan Shah, MD

120. Jess Kane: Your Cells Are Leaking, Here's How to Fix Them


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Have you ever wondered why you can be "doing everything right" with your health and still feel inflamed, foggy, or depleted? The more I study longevity, the more I am convinced this has less to do with the latest hack and more to do with something very basic that we almost never talk about: the integrity of the cell membrane. Every process in the human body begins at the level of the cell membrane, and in today's world, that membrane is under constant attack from toxins, infections, chemicals, and everyday stressors.

In this episode of Extend, I sit down with Jess Kane to explore why phosphatidylcholine (PC) may be the most critical nutrient we're not talking about, how modern exposures create "leaky cells," and why nearly all of us are now deficient in the lipids required to keep our DNA, mitochondria, and metabolic pathways safe. We break down the original PK Protocol, the role of PC in detoxification and brain health, and the steps anyone can take to rebuild membrane resilience and restore energy at the cellular level.

Jess Kane is the Chief Marketing Officer and third-generation co-owner of BodyBio, a family-led company pioneering science-backed solutions for cellular health, mitochondrial support, and anti-toxin resilience. She blends strategic insight with deep biochemical knowledge, helping BodyBio earn the trust of more than 35,000 healthcare practitioners worldwide. Jess is dedicated to educating the public on foundational lipids like phosphatidylcholine and the critical role they play in modern health.

What's Discussed:

  • (00:00) The "Bubble" Shield: How Your Cell Membrane Actually Works

  • (03:31) Leaky Cells: Toxins, Viruses, and the New Epidemic of Cellular Damage

  • (04:40) Fats That Build (or Break) Your Cell Membrane

  • (11:19) "Our Lipids Are Under Attack": Low-Fat Diets, Modern Toxins, and Metabolic Chaos

  • (15:42) Detox, Rebuild, Repeat: Using PC, TUDCA & Glutathione to Repair from the Inside Out

  • (27:49) Brain Fog, Acetylcholine, and Why PC Is a Hidden Brain Nutrient

  • (33:35) Skin, Aging, and What Healthy Cells Actually Look Like

  • (37:23) Seed Oils, Oxidized Fats, and How to Swap In the Right Lipids

Thank You for Our Sponsors:

NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram:@darshanshahmd

Learn more about Jess Kane:

Blog: https://bodybio.com/blogs/blog

TikTok: @jesskaneb

X: https://x.com/jesskberman

Instagram: jesskane

Instagram: bodybio

TikTok: body.bio

Facebook: BodyBio

Website: Bodybio.com

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Extend Podcast with Darshan Shah, MDBy Darshan Shah, MD

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