Extend Podcast with Darshan Shah, MD

132. Nathalie Niddam: Reverse Aging Signals with Bioregulators and Peptides


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Most people assume fatigue, low energy, and age-related decline are unavoidable. What if supporting your body, optimizing recovery, and enhancing longevity were about activating the right systems, rather than chasing symptoms?

In this episode of Extend, we sit down with Nathalie Niddam, holistic nutritionist, longevity educator, and host of the Longevity Podcast with Nathalie Niddam, to unpack how bioregulators, mitochondrial peptides, and targeted nutritional strategies can support cellular health, improve energy, and enhance resilience over time.

We also explore how bioregulators influence DNA expression, how mitochondrial peptides restore cellular function, and how small, consistent interventions in nutrition and lifestyle can amplify overall vitality and longevity.

Nathalie Niddam is a longevity educator and holistic nutritionist who hosts the Longevity Podcast, where she shares science-backed strategies, biohacking insights, and practical tools for optimizing health, energy, and long-term performance.

What We Discuss:

(00:00) Why Aging Isn't Inevitable and How Bioregulators Work

(06:12) The Russian Origins of Bioregulator Research and Key Studies

(13:45) How Bioregulators Support Organ Function and Longevity

(21:30) Integrating Bioregulators with Peptides for Maximum Benefit

(29:10) Mitochondrial Health: SS31, MOTS-C, Humanin, and Phospholipids

(36:55) Testing and Optimizing Fatty Acids and Deuterium for Cellular Energy

(44:40) Practical Protocols: Stacking Bioregulators for Liver, Cardiovascular, and Metabolic Support

(51:25) The Role of Lifestyle, Stress, and Nervous System in Aging Reversal

Thank You to Our Sponsors:

NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/

Learn more about Dr. Shah:

Website: https://www.drshah.com/

Clinic: https://www.next-health.com/

Instagram:@darshanshahmd

Learn more about Nathalie Niddam:

Instagram: @nathalieniddam

Website: https://www.natniddam.com/

Linkedin: Nathalie Niddam

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Extend Podcast with Darshan Shah, MDBy Darshan Shah, MD

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