Endurance Eats

31: Caffeine Strategies: Researched-Backed Tips for Endurance Athletes


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In this episode of the Endurance Eats podcast, Alex Larson interviews Nathaniel Jenkins about the effects of caffeine on endurance performance. They discuss the benefits of caffeine, including improved performance and altered perception of effort, as well as the potential downsides such as GI distress and sleep interference. Jenkins explains the genetic factors influencing caffeine metabolism and provides insights on optimal dosages and timing strategies for endurance athletes. The conversation concludes with a look at future research directions in caffeine and its health-related benefits.

00:00 Introduction to Caffeine and Endurance Performance

02:27 Benefits of Caffeine for Endurance Athletes

05:10 Understanding the Downsides of Caffeine

07:48 Caffeine Metabolism and Genetic Factors

10:24 Optimal Caffeine Dosage for Performance

12:43 Caffeine Strategies for Endurance Events

24:47 Strategic Use of Caffeine in Endurance Sports

26:15 Caffeine Administration Methods and Their Effects

29:00 Caffeine's Impact on Perception of Effort

30:16 Managing GI Distress with Caffeine

33:29 Caffeine and Sleep: Timing Matters

36:50 Future Research Directions in Caffeine Studies


Guest Bio:

Dr. Nathaniel D. M. Jenkins, PhD, FAHA, is an Associate Professor in the Department of Health and Human Physiology at the University of Iowa, where he leads the Integrative Laboratory of Applied Physiology & Lifestyle Medicine. His research focuses on how early life stress, including adverse childhood experiences, contributes to the development of cardiovascular and metabolic diseases, and how resistance training can be used as an intervention to improve cardiometabolic health, particularly in aging populations.

A Fellow of the American Heart Association, Dr. Jenkins has been recognized for his contributions to lifestyle and cardiometabolic health research. He has served on national committees for both the American Heart Association and the National Strength and Conditioning Association, helping shape the future of research and practice in his field. With a passion for bridging physiology, behavioral science, and clinical application, Dr. Jenkins’s work offers valuable insights into prevention and long-term health outcomes.


Resources Mentioned in This Episode:

  •  Apply for 1:1 Coaching with an ALN Dietitian 

  • Caffeine Recommended products


Connect with Me:

  • Instagram: @alexlarsonnutrition

  • Website: alexlarsonnutrition.com


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This episode is brought to you by Skratch Labs — real-food, performance-driven nutrition that’s easy on your gut and powerful in its effectiveness. Check them out for mixes, chews, bars, and more that help you train harder and recover smarter.

Use code ENDURANCEEATS20 for 20% off!


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Endurance EatsBy Alex Larson

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