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In this episode of The Incubator Podcast, Ben and Daphna sit down with Dr. Alex Kemper, Division Chief of Primary Care Pediatrics at Nationwide Children’s Hospital and Editor-in-Chief of Pediatrics. Dr. Kemper served as chair of the American Academy of Pediatrics subcommittee that authored the 2022 revision of the neonatal hyperbilirubinemia guidelines.

Together, they explore the motivations behind revisiting the 2004 guideline, the major changes introduced, and how these revisions are shaping clinical care. Dr. Kemper explains why treatment thresholds for phototherapy were raised, the careful balance between avoiding unnecessary interventions and preventing kernicterus, and the rationale for moving away from the risk stratification nomogram. The discussion highlights phototherapy as an effective but not benign therapy—one that can disrupt bonding, prolong hospitalization, and create family stress when overused.

Listeners will gain insight into the complexities of evidence review, the challenges of consensus-building over eight years of work, and the importance of shared decision-making and reliable follow-up after discharge. This conversation not only demystifies the new guidelines but also reframes the way clinicians think about jaundice management, risk stratification, and the broader impact on families.

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As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!