November 23, 2025

#382 – 🗞️ NeoNews - What Should Neonatal Teams Prioritize This Winter? RSV Coverage Gaps, Congenital Syphilis, and New Research Shaping Care

1 hour

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In this episode of NeoNews, the team returns from a brief hiatus with a refreshed format and a packed review of neonatal stories dominating recent headlines. Eli, Ben, and Daphna open with updates on RSV prevention, highlighting new MMWR data showing significant gaps in nirsevimab and maternal vaccine uptake—despite strong evidence and renewed availability. They discuss how supply chain issues, insurance delays, and vaccine confusion continue to limit access, and they emphasize the unique role neonatologists can play in counseling families early and often. The hosts also review concerning national trends in congenital syphilis, noting that many affected infants had parents who received prenatal care but were never tested—an avoidable systems failure with major downstream costs. Additional segments cover the severity of last year’s influenza season, the emergence of new RSV monoclonal antibodies, and the rising use of polygenic risk scoring in IVF. The team reflects on the ethical tension between innovation and eugenics concerns, and how neonatal providers can prepare for these conversations. Finally, the deep dive explores Sherri Fink’s powerful reporting on trisomy 18, variability in care across institutions, and the growing emphasis on transparent, value-driven shared decision-making with families.

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As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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