November 21, 2023

56: NF-Kappa B: The Orchestra of Health and its Modulation Melody | Your Complete Guide

1 hour

Today, my friends, we are going to discuss a very hot topic, NF-Kappa B. What is NF-Kappa B? Friends you want to know this information, you NEED to know this information. Who is this episode for? Do you suffer with autoimmunity, diabetes, atherosclerosis, asthma, eczema, osteoporosis… do you have pain, fatigue, etc.? Are you battling with any chronic conditions? You likely have an upregulated NF-kappa B. Approximately 1 in 3 adults worldwide have multiple chronic conditions. This is a must not miss episode my friends!

Today’s show was prompted by a question from Eric. Eric asked “with inflammation, are there any other strategies aside from taking ibuprofen that can help? I read that chronic use of ibuprofen is not good for my health.” Thank you, Eric, for your question. As a reminder, if you have an idea for or show, a question or comment – send me a DM, email, comment on a YouTube video and I will give you a shout out! I do not have the background on what type of inflammation Eric is referencing, but today we are getting into the nitty gritty of one of the keystone players in inflammation and what to do about it.

Today’s outline:

1. What is NF-κB

2. Activation Mechanisms

3. NF-κB's Impact on Cellular Functions

4. NF-κB Implications with Health and Disease

5. Modulating NF-κB Activity

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Just a quick disclaimer that this podcast is meant for educational purposes only and is not meant to diagnose or be a substitute for medical advice from your practitioner. Never disregard professional medical advice or delay seeking care because of anything you heard on the podcast or on my website.

Interesting Articles:

https://www.nature.com/articles/sigtrans201723

https://www.nature.com/articles/cr201113

https://www.frontiersin.org/articles/10.3389/fcell.2019.00154/full

https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.13958

https://autoimmunhighlights.biomedcentral.com/articles/10.1186/s13317-020-00135-z

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963006/

https://www.sciencedirect.com/science/article/pii/S0168170223000485

https://www.nature.com/articles/cddis2016250

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