The GutFit Nutrition Podcast

8: PCOS & Dysbiosis: How Your Gut Microbes Influence Your Hormones With Sana Motlekar RD, MPH


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In today’s Episode, we’re exploring PCOS and dysbiosis—specifically, how your gut microbiome can influence the development and management of Polycystic Ovary Syndrome. We break down the science behind the gut-hormone connection and what it means for those navigating gut symptoms like IBS, SIBO, or GERD alongside hormonal conditions like PCOS. 

⏱️ Chapters:

  • (0:35) – Intro
  • (1:24) – Exploring the Gut-Hormone Connection in PCOS
  • (2:07) – Guest Intro: Sana Motlekar, PCOS & Metabolic Health RD
  • (4:35) – Sana’s Personal Journey & Cultural Focus
  • (8:25) – What Is PCOS? Diagnosis Criteria Explained
  • (10:35) – Misdiagnosis & Dismissal of PCOS Symptoms
  • (15:49) – Root Causes: Insulin Resistance, Stress, Inflammation
  • (21:31) – Conventional vs. Functional Approaches (Metformin, Birth Control)
  • (27:15) – The Role of Gut Health in Hormone Regulation
  • (33:35) – IBS, Dysbiosis & PCOS – What's the Link?
  • (39:39) – How Gut Microbes Impact Estrogen & Androgens
  • (43:57) – Top Nutrition Strategies for Managing PCOS
  • (49:10) – Lifestyle Factors: Products, Toxins & Stress
  • (52:52) – Movement & Exercise For PCOS
  • (57:05) – Can You Do HIIT with PCOS?
  • (1:00:35) – Final Takeaways


👤 Today’s Guest: Sana Motlekar

Sana Motlekar is a Registered Dietitian with a Master of Public Health, specializing in PCOS, weight loss, fatty liver, and diabetes. Based in Toronto, Sana brings over 12 years of experience helping women feel at home in their bodies without restriction, shame, or sacrificing their cultural food roots.

📌 Sana’s Website: https://www.pcosweightlossdietitian.com/

📌 Sana’s Instagram: https://www.instagram.com/pcos.weightloss.dietitian/


👩🏻‍💻 RESOURCES & LINKS MENTIONED: ⤵️

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If the GutFit Nutrition Podcast is giving you value - helped your digestion and fitness, made you rethink how you approach your gut health, please consider leaving a review! 🎧 

If you have questions for my listener Q & A episodes, you can submit them here, or send me an email at ⁠[email protected]⁠. See you soon!

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The GutFit Nutrition PodcastBy Leigh Merotto, Dietitian | IBS, Gut Health and Fitness Expert

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