More than 200,000 cases of syphilis were reported in the U.S. in 2022, the highest number of cases since the 1950s. In this episode, pediatric ID physician Buddy Creech, MD, MPH, FPIDS, speaks to Laura Bachmann, MD, MPH, Chief Medical Officer in the Division of STD prevention at the CDC, about attributing factors and what providers can do to address this rising epidemic.