ID:IOTS - Infectious Disease Insight Of Two Specialists

By Infectious Disease: Insights of Two Specialists

What's ID:IOTS - Infectious Disease Insight Of Two Specialists about?

Join Callum and Jame, two infectious diseases doctors, as they discuss everything you need to know to diagnose and treat infections. Aimed at doctors and clinical staff working in the UK. 

Episode notes here: https://t.ly/8DyqW 

Queries, comments, suggestions to [email protected] 

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ID:IOTS - Infectious Disease Insight Of Two Specialists episodes:

05.20.2024
80. A Poem on POET
Join us for this special 80th episode celebrating Jame's favourite trial.https://www.nejm.org/doi/full/10.1056/NEJMoa1808312Prep notes (including the images referred to in the poem) here. Special thanks to the Wikiguidelines Endocarditis crew for their work summarising the evidence this poem was based on. Support...
05.06.2024
79. A Précis on Penicillin Binding Proteins
Presenting: More on Penicillin-Binding-Proteins than you realistically ever need to know! What is the difference between Gram positive and negative bacteria's cell walls?What is a Penicillin Binding Protein (PBP)?Why are they called PBPs?What do PBPs do?What makes MRSA resistant to...
04.21.2024
78. Pharmacokinetics summary
One PK table to rule them allOne table to find themOne table to bring them all And in the darkness blind them… …with awesome antibiotic PK facts you can use to bedazzle your friends and enemies alike! Prep notes here....
04.08.2024
77. Illuminating Elimination
The last Pharmacokinetics episode had finally been …Excreted! This episode covers the ‘drug out’ bit of pharmacokinetics, including things such as: -What is clearance? -how to calculate half life and -doesn’t everything leave through the kidneys anyway?...
03.24.2024
76. Dithering on distribution
It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).What exactly is the volume of distribution?...
03.11.2024
75.Blethering about Bioavailability
It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice. Want...
02.25.2024
74. Nobbling the Nonfermentors: Burkholderia mallei - Glanders
In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders. We did it. We got to the end. Nonfermentors... Nobbled. Support the Show.Questions, comments, suggestions...
02.13.2024
73. SABATaddendum
Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state. Final article here:Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an...
02.12.2024
72. IDIOTS journal club: the SABATO trial
JOURNAL CLUB, YO, IT’S A SABATO!!!Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!In the next episode we'll give...
01.29.2024
71.Nobbling the Nonfermentors: Burkholderia pseudomallei - Melioidosis
In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.This episode was based disproportionately on the following article, and we extend our thanks to the...
01.08.2024
70. Part 2 FRCPath reflections and Desert Island Antibiotics
In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert...
12.25.2023
69. Choosing an antimicrobial
How do you think about antibiotics?This Christmas we give the best gift of all: no puns in an episode.Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.Here are the show notes for this...
12.18.2023
68. Nobbling the Nonfermentors: Burkholderia cepacia Complex
Did you think the evidence base for Stenotrophomonas was bad? Well allow us to introduce you to Burkholderia cepacia complex!BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very)...
12.04.2023
67. FIS highlights 3 - Fungal Diagnostics, Linezolid & Serotonin Syndrome, SABATO Trial, Rabies, PK/PD Dosing of Antibiotics
Callum and Jame wrap up their thoughts on the recent FIS conference. Support the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying...
11.27.2023
66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.htmlMentioned in episode:ESCMID brain abscess guidelines: https://www.sciencedirect.com/science/article/pii/S1198743X23003993# ORAL study protocol: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021-05783-8 ACBLM/ALM: https://www.acb.org.uk/Pathology networks: https://www.england.nhs.uk/pathol...
11.20.2023
65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode:UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our-services/find-service/medical-specialties-1/hlh-serviceSNAP trial: https://www.snaptrial.com.au/ SNAP trial email: [email protected] (pre-print) https://www.medrxiv.org/content/10.1101/2023.07.03.23291932...
11.06.2023
64. Let’s talk tests with Let’s Talk Micro
In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast.Listen in for a discussion on what a Biomedical Scientist is and how to become one. We explore the key details that clinicians need...
10.23.2023
63. Nobbling the Nonfermentors: Stenotrophomonas maltophilia
Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish. Unlike Pseudomonas & Acinetobacter, Steno is much less commonly seen outside of ITU & the immunocompromised; but when it...
10.09.2023
62. Nobbling the Nonfermentors: Acinetobacter Part 2: Resistance & CRAB
In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus complex. Do have a look at the prep notes for...
10.02.2023
61. Nobbling the Nonfermentors: Acinetobacter Part 1
In this episode, Callum and Jame go over the second big family of nonfermentors, Acinetobacter. In part 1 we talk about the organisms themselves, risk factors, clinical syndromes and diagnostics before talking a little about treatment. In Part 2 (released...
09.11.2023
60. Nobbling the Nonfermentors: Pseudomonas Part 2 - Treatment & Resistance
In part 2, we discuss the limited treatment options for pseudomonas infection, some wildcard options and the resistance mechanisms that make Pseudomonas such a tricky bugger to treat! Support the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes...
09.04.2023
59. Nobbling the Nonfermentors: Pseudomonas Part 1
It was a long time coming, but it’s here. Jame and Callum set off on our mini-series, Nobbling the Nonfermentors, starting with an introduction to glucose-nonfermenting organisms before moving on to the biggie: Pseudomonas aeruginosa! Part 2 next week covers...
08.29.2023
58. Mythbusting Cidal vs Static with Microbe Mail
Jame and Callum were delighted to be invited as guests to the podcast Microbe Mail by host Vindana (Vin) Chibabhai. Check out the Microbe Mail podcast:https://microbemail.captivate.fm/ @microbemail We discuss how bactericidal and bacteriostatic are defined, what the minimum inhibitory...
08.22.2023
57. Antimicrobial stewardship begins at home
Jame and Callum are together in person to talk about the importance of keeping your house in order. Being an infection specialist does not automatically make you an antimicrobial steward. We reflect on some challenges to being an antimicrobial steward...
08.07.2023
56. Antibiotics, Breastfeeding and Infant Health
We were delighted to be joined by Dr Anastasia "Tash" Theodosiou to talk about breastfeeding, antibiotics and the risks of antibiotic harm to mum and baby. Tash is an infectious diseases/medical microbiology trainee, host of the HelloMicro blog and has...
07.28.2023
55. The ID:IOTS annual report 2023
2 years. It’s been a hell of a ride. Here’s to 2 more. Links from this episode: KASIC 1-page evidence-summary on aminopenicillins for resistant enterococcal UTIs: https://bit.ly/44CtNnqAUDIENCE SURVEY!!! Please do fill this out, it would mean a lot to...
07.24.2023
54. Antibiotics for UTIs
This is the urine antibiotic drug penetrance you never knew you wanted. Jame might be prouder of this than his own children. Callum, as you will be able to tell, remains indifferent*. Figure out which antibiotics you can trust, and...
07.10.2023
53. Clobbering CAUTI
Catheter-associated UTI: Callum’s nemesis. His white whale. His Sauron. His favourite rant. Want to know how favourite? Listen on! Useful links (see show notes for more)RICAT studyChlorhexidine meatal cleaningSupport the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes...
06.26.2023
52. Escalation Emancipation
Loyal Listeners! Free yourselves from this outdated language! Emancipate your hospitals from 'Escalation antibiotics'! In today's episode, Callum and Jame rant for 35 minutes about how we talk about changing therapy, and how talk of escalating antibiotics leads to desire...
06.13.2023
51. Taking the Piss: Urine Culture, Unravelled
The title says it all. We're going back to the lab for this discussion. Join Jame and Callum as they have an in depth discussion about the nature of urine culture. Prep notes for this episode available here. Support the...
05.30.2023
50. FRCPath exams for clinical scientists - prepping to pass
Ever wondered what a clinical scientist is or how to become one? Are you a clinical scientist and looking to sit the FRCPath exams? Join Jame and Callum as they talk to Phillipa Burns and Vicki Fleming about their experiences...
05.06.2023
49. Penicillin Allergy 2: Delabel Harder
Welcome to the party pal! The penicillin allergy assessment and delabelling party, that is. Callum takes Jame through the latest evidence base in antibiotic allergy in general, and beta lactam allergy assessment and management in particular. Links: PENFAST Score paper:...
05.01.2023
48. ECCMID highlights part 4: Antimicrobial stewardship, Antibiotics at end of life, Behaviour science and tick borne infections
Join Callum with guests Morgan Evans, Olivia Hawkes and Katy Hill for the final(?) part of the ECCMID 2023 highlightsECCMID sessions discussed:- Antimicrobial stewardship poster session- Ethical dilemmas with antimicrobial therapy- The value of diagnostic information for antimicrobial stewardship- Tick...
04.28.2023
47. ECCMID highlights part 3: Mythbusting, Sporotrichosis, phages, AMR, Paeds, Grand Round
Join Callum with guests Andrew Seaton, Marianna Avellar, Hannah Pymont, Eva Garmendia, Sanjay Patel and Dave Hettle live from ECCMID 2023. ECCMID sessions discussed:- Fairytales or reality, checking some eminence paradigms for treatment of severe infections- Neglected tropical skin diseases-...
04.26.2023
46. ECCMID highlights part 2: UTI antibiotic stewardship, CMV & BK, Responsible Publishing, HLH
Join Callum with Guests Robert Ball, Kelly Bicknell & Rob Read live from ECCMID 2023. ECCMID sessions discussed:Antibiotic stewardship for urinary tract infections: challenges and opportunitiesViral Infection in immunosuppressed patients: what is new?Responsible publishing in CM/IDSecondary haemophagocytic lymphohistiocytosis and infectious...
04.24.2023
45. ECCMID highlights part 1: Archaea, Digitalisation and the IDSA
Callum is reunited with Jame following their separation at ECCMID 2023. Callum shares some highlights including Archaea and their role in human health, Digitalisation within the microbiology lab and the ESCMID/IDSA interviewLinks to publications on Archaea:https://www.moissleichingerlab.com/projects/https://twitter.com/chmoei?lang=enDigitalisation and machine learning in...
04.03.2023
44. The Basics of Beta Lactamase Inhibitors
Jame rides solo today, going over the beta-lactamase inhibitors, old and new, how to think about them and when to use them in anger. New Show notes format! Available at https://idiots.notion.site/Beta-Lactamase-Inhibitors-f9999b6a4867470996a31c53e661b5acNB: For now all old show notes are available in...
03.20.2023
43. ABIM ID board exams - Prepping to Pass
Jame and Callum are joined by the one and only Sara Dong of Febrile fame to look at the American Board of Internal Medicine's Infectious Disease Certification Exam. Support the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes...
03.06.2023
42. FRCPath part 1/CICE - Prepping to Pass
Jame and Callum are joined by semi-recent FRCPath Microbiology part 1 exam passers Callum and Jame to discuss how best to prepare for this exam. This exam is sat by all infection trainees in the UK, as well as...
02.20.2023
41. Bugs Without Borders: a conversation with Microbe Mail!
Jame and Callum are joined by Vin from Microbe Mail to discuss the management of Difficult to Treat Resistance (DTR) Gram negative infections in South Africa.If you haven't already check out Microbe mail for a high quality infection podcast linking...
02.06.2023
40. FRCPath part 2 Microbiology exam - Prepping to Pass
Jame and Callum are joined by recent FRCPath Microbiology part 2 exam passers Olly and Rob to discuss how best to prepare for the exam. This is the final exam required to qualify as a medical/clinical microbiologist in the UK....
01.23.2023
39. ID:IOTS Journal Club: 3 days treatment for CAP
It's time for journal club! Jame and Callum discuss community acquired pneumonia treatment and a paper from 2021 which examines shorter duration therapy for patients responding to therapy.Paper discussed:Dinh, Aurélien et al. “Discontinuing β-lactam treatment after 3 days for patients...
01.09.2023
38. Gram positive vs negative bacteraemia - SHOWDOWN!
In this episode as requested on twitter (sort of), Callum & Jame compare and contrast Gram positive & negative bacteraemia. Happy new year!Please also see our older episode on bloodstream infection: www.buzzsprout.com/1782416/9162105-5-back-to-bacteraemiaSABATO trial details here: https://twitter.com/sebpoule/status/1518496524552056833?s=46&t=Dre0YLRm_gwnKQ8OakDarwSupport the Show.Questions, comments,...
12.25.2022
37. The Tragedy of Plazomicin
This Christmas, Jame shares a tale of woe: the rise and fall of Plazomicin, a hapless victim of antibiotic market forces. The conversation then proceeds/degenerates into a discussion of the economics of Antimicrobials in general, with a focus on the...
12.12.2022
36. Urinalysis paralysis
Join Jame and Callum as they take a deep dive into urinalysis, a commonly (mis)used test for UTI (and other conditions). This test put you into murky waters when used clinically and we hope to give some information to avoid...
11.28.2022
35. ...arriving at ACEK
Callum and Jame discuss the HACEK organisms (apart from Haemophilus which we discussed in episode 32). Support the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep...
11.14.2022
34. Arguing about atypicals
An atypical episode about pneumonia. Callum and Jame discuss their pet peeves. Support the Show.Questions, comments, suggestions to [email protected] or on X/Threads @IDiots_podPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying...
10.25.2022
33. The ID:IOTs Guide to Aminoglycosides
Callum and Jame talk about everyone's favourite antibiotic class that covers Staph, Pseudomonas and Gram negatives, is predominantly renally excreted and isn't a quinolone, the aminoglycosides. We go over classification, mechanism of action, spectrum, resistance mechanisms, PK/PD, penetrance to various...
10.10.2022
32. Hurrying through Haemophilus
Join Jame and Callum as they talk you through Haemophilus spp. Turns out that Haemophilus influenzae isn't the cause of Influenza. We answer some questions such as: What are X and V? Suggestions and comments to [email protected] or @IDiots_podIf you...
09.26.2022
31. Salmonella and Shigella
Join Jame and Callum as they discuss the two titans of diarrhoea, Salmonella and Shigella. Who knew Salmonella species were so complex? Jame explains something that will SHOCK you about Shigella (maybe).Suggestions and comments to [email protected] or @IDiots_podIf you are...

What's ID:IOTS - Infectious Disease Insight Of Two Specialists about?

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ID:IOTS - Infectious Disease Insight Of Two Specialists episodes:

80. A Poem on POET

79. A Précis on Penicillin Binding Proteins

78. Pharmacokinetics summary

77. Illuminating Elimination

76. Dithering on distribution

75.Blethering about Bioavailability

74. Nobbling the Nonfermentors: Burkholderia mallei - Glanders

73. SABATaddendum

72. IDIOTS journal club: the SABATO trial

71.Nobbling the Nonfermentors: Burkholderia pseudomallei - Melioidosis

70. Part 2 FRCPath reflections and Desert Island Antibiotics

69. Choosing an antimicrobial

68. Nobbling the Nonfermentors: Burkholderia cepacia Complex

67. FIS highlights 3 - Fungal Diagnostics, Linezolid & Serotonin Syndrome, SABATO Trial, Rabies, PK/PD Dosing of Antibiotics

66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR

65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC

64. Let’s talk tests with Let’s Talk Micro

63. Nobbling the Nonfermentors: Stenotrophomonas maltophilia

62. Nobbling the Nonfermentors: Acinetobacter Part 2: Resistance & CRAB

61. Nobbling the Nonfermentors: Acinetobacter Part 1

60. Nobbling the Nonfermentors: Pseudomonas Part 2 - Treatment & Resistance

59. Nobbling the Nonfermentors: Pseudomonas Part 1

58. Mythbusting Cidal vs Static with Microbe Mail

57. Antimicrobial stewardship begins at home

56. Antibiotics, Breastfeeding and Infant Health

55. The ID:IOTS annual report 2023

54. Antibiotics for UTIs

53. Clobbering CAUTI

52. Escalation Emancipation

51. Taking the Piss: Urine Culture, Unravelled

50. FRCPath exams for clinical scientists - prepping to pass

49. Penicillin Allergy 2: Delabel Harder

48. ECCMID highlights part 4: Antimicrobial stewardship, Antibiotics at end of life, Behaviour science and tick borne infections

47. ECCMID highlights part 3: Mythbusting, Sporotrichosis, phages, AMR, Paeds, Grand Round

46. ECCMID highlights part 2: UTI antibiotic stewardship, CMV & BK, Responsible Publishing, HLH

45. ECCMID highlights part 1: Archaea, Digitalisation and the IDSA

44. The Basics of Beta Lactamase Inhibitors

43. ABIM ID board exams - Prepping to Pass

42. FRCPath part 1/CICE - Prepping to Pass

41. Bugs Without Borders: a conversation with Microbe Mail!

40. FRCPath part 2 Microbiology exam - Prepping to Pass

39. ID:IOTS Journal Club: 3 days treatment for CAP

38. Gram positive vs negative bacteraemia - SHOWDOWN!

37. The Tragedy of Plazomicin

36. Urinalysis paralysis

35. ...arriving at ACEK

34. Arguing about atypicals

33. The ID:IOTs Guide to Aminoglycosides

32. Hurrying through Haemophilus

31. Salmonella and Shigella