In which Jame waxes lyrical about pharmacodynamic target attainment and its role in breakpoint setting and dosing of antibiotics, and how you can apply it in clinical practice. 

Take a look at the prep notes for this one, a picture says a thousand words!

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The POET trial was the biggest endocarditis trial in some time, and since 2019 has changed how we manage these patients. But how to implement oral regimens for Endocarditis? 

Jame speaks to Nik Rae, Consultant Physician, on how they implemented the use of oral antibiotics for endocarditis patients in Ninewells Hospital, and how you can too! (in your own hospital, not Ninewells, the're already doing it). 

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

How do you decide which antimicrobial to use? This is a follow on from episode 69, 'Choosing an antimicrobial'. We did an overview of spectrum and syndromes... But now let's dive into the details!

We consider the details of how to choose an antibiotic in simple, complicated and complex situations. 

We also talk about the Cynefin Framework for decision making in various circumstances; Don't worry if you don't know what that is; neither did Jame before this episode was recorded! 

Notes for this episode here: https://idiots.notion.site/144-Choosing-an-Antimicrobial-Host-Microbe-Drug-Factors-2d76a1ea09d8814787ccfc26fe779b3a 

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Paediatric AMS? Surely there aren't any issues with antimicrobial use in paediatrics?!

Jame hears from Dr Charlotte Fuller and Dr Sanjay Patel that yes, yes there is a problem! And YOU can do something about it.

Listen in to hear the answers to these questions:

• What do we know about AMR and antimicrobial use in children? 
• What are the barriers to responsible antimicrobial use in children?
• How can DGH AMS teams and paediatrics support each other?  
• Are there any other paediatric-specific considerations for infection prevention, diagnosis and management?
• Where can microbiologists learn more about paediatric infection? HINT it is here: https://uk-pas.co.uk/ and here https://bsac.org.uk/paediatricpathways/

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

Access 

Watch

Reserve (IE the cool stuff)

What are they? Where are they? WHO ARE THEY? 

Listen on and find out! (Looking at the prep notes strongly advised for this one). 

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

There's nothing new under the sun... except for these new antifungals which we will now educate you on! 

• One's an inhaled azole (OK not that new)
• One's sort of an echinocandin (shut up)
• Two are unpronounceable (but related to fungicides which we're using already)

And Alyssa and Jame are joined by Dr Neil Stone, ID:IOTS Podcast Novel Antifungal Agent Correspondent, to guide you through it all! 

Support the show

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

Callum was recently on the Primary Care Knowledge Boost podcast (https://pckb.org/), talking about what happens to microbiology specimens sent in to the lab. He did so well we thought we'd share it with you here! Enjoy... 

Original podcast blurb here: 

---

Doctors Lisa and Sara are joined by Medical microbiology and Infectious Diseases Consultant Dr Callum Mutch to follow the journey of a urine sample and a throat swab as they are processed. We discuss the important points to get right in the pre-analytical, analytical and post analytical stages of their journeys. Some fascinating insights (including how the clinical details can affect what is tested for) that have changed our practice for the better.

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Process your Polyene Prescribing Paralysis by partaking in this proliferous podcast pondering on the particulars of these P-harmacological agents.* 

*Alyssa had no part in the making of this podcast description. 

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

Jame and Callum are joined by Christina Petridou. In this episode we give you an overview of ticks and the key infections they transmit..., but NOT Lyme disease.

Some of the infections we DO cover include: Rickettsiosis (spotted fever group), relapsing fevers, anaplasmosis, ehrlichiosis, babesiosis, TBE & CCHF. 

Not Lyme. THIS IS NOT A LYME DISEASE EPISODE. 

Show notes (including lots of summary tables and horrible tick pics) for this episode are here.

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Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app! 

Flucytosine. A much maligned antifungal, consigned to adjuvant use in Cryptococcus... 

WELL THAT CHANGES... well not today because the resistance barrier is shockingly low, but at least in 20m time you'll know all you need to about 5-FC! 

Support the show

Support us on: 

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BuyMeACoffee: https://www.buymeacoffee.com/idiotspod

Prep notes for completed episodes can be found here (Not all episodes have prep notes).

If you are enjoying the podcast please leave a review on your preferred podcast app!