In this two-part podcast, Dr. Anthony Bozzo, McGill University, and Fred Jiawen Deng, University of Toronto, join moderator Dr. Craig Nielsen, Cleveland Clinic, to discuss the newest AI-powered platforms, such as ChatGPT (Chat Generative Pre-trained Transformer). Listen as they aim to demystify the role of ChatGPT and similar technologies in clinical settings, highlighting their limitations and current applications and discussing future directions in research and development.