
Sign up to save your podcasts
Or


In this episode of AI Basics, Jason sits down with CapitalG partner Jill Chase to break down how AI is reshaping the startup ecosystem — from founders to investors to incumbents. They cover how CapitalG (Alphabet’s independent growth fund) thinks about the AI stack, why speed alone isn’t enough for startups today, and how to build durable advantages in a world where anyone can copy your product. Jill shares insights from portfolio companies like Motif (next-gen CAD for architecture) and Abridge (AI-powered doctor’s scribe), plus how startups can use AI “in the business” (product) and “on the business” (ops, GTM, etc). They also explore the transition from copilots to agents — and what that means for the next wave of software. If you’re building or investing in AI, this is a must-watch.
*
Timestamps:
(0:00) Jason kicks off the show
(1:10) CapitalG's investment strategy in AI
(3:04) Understanding value in AI investments
(5:16) Durability in AI startups and market challenges
(10:18) Practical applications of AI in business
(17:52) Case studies of successful AI startups
(21:35) Building massive businesses with small teams
(23:55) Evolution from AI copilots to autonomous agents
*
Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai
*
Check out all of the Startup Basics episodes here: https://thisweekinstartups.com/basics
Check out Google Cloud: https://cloud.google.com/
Check out CapitalG: https://www.capitalg.com/
*
Follow Jill:
LinkedIn: https://www.linkedin.com/in/jill-greenberg-chase-53747538/
X: https://x.com/jillchase124
*
Follow Jason:
X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
*
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
By Jason Calacanis4.2
12691,269 ratings
In this episode of AI Basics, Jason sits down with CapitalG partner Jill Chase to break down how AI is reshaping the startup ecosystem — from founders to investors to incumbents. They cover how CapitalG (Alphabet’s independent growth fund) thinks about the AI stack, why speed alone isn’t enough for startups today, and how to build durable advantages in a world where anyone can copy your product. Jill shares insights from portfolio companies like Motif (next-gen CAD for architecture) and Abridge (AI-powered doctor’s scribe), plus how startups can use AI “in the business” (product) and “on the business” (ops, GTM, etc). They also explore the transition from copilots to agents — and what that means for the next wave of software. If you’re building or investing in AI, this is a must-watch.
*
Timestamps:
(0:00) Jason kicks off the show
(1:10) CapitalG's investment strategy in AI
(3:04) Understanding value in AI investments
(5:16) Durability in AI startups and market challenges
(10:18) Practical applications of AI in business
(17:52) Case studies of successful AI startups
(21:35) Building massive businesses with small teams
(23:55) Evolution from AI copilots to autonomous agents
*
Uncover more valuable insights from AI leaders in Google Cloud's 'Future of AI: Perspectives for Startups' report. Discover what 23 AI industry leaders think about the future of AI—and how it impacts your business. Read their perspectives here: https://goo.gle/futureofai
*
Check out all of the Startup Basics episodes here: https://thisweekinstartups.com/basics
Check out Google Cloud: https://cloud.google.com/
Check out CapitalG: https://www.capitalg.com/
*
Follow Jill:
LinkedIn: https://www.linkedin.com/in/jill-greenberg-chase-53747538/
X: https://x.com/jillchase124
*
Follow Jason:
X: https://twitter.com/Jason
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
*
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com

537 Listeners

1,089 Listeners

2,170 Listeners

338 Listeners

3,990 Listeners

226 Listeners

9,927 Listeners

511 Listeners

169 Listeners

131 Listeners

467 Listeners

35 Listeners

21 Listeners

121 Listeners

44 Listeners