This audio program includes a discussion of a study that used an algorithm to search electronic health records for clinical information relevant to the Research Domain Criteria; an article on predicting the transition from mild cognitive impairment to dementia; a trial on reducing reactivity to alcohol cues in patients with alcohol dependence; a study of the relationship between C-reactive protein and symptoms of PTSD; a trial examining the influences of health coaching for overweight persons with serious mental illness; and an intriguing short essay about correspondence between Charles Darwin and the head gardener at an English mental institution. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of adjustment disorder in a health care worker with Ebola, a case of psychotic symptoms that improved with a gluten-free diet, medication prescribing for first-episode schizophrenia, outcomes for young people at ultra-high risk for psychosis who do not transition to psychotic disorders, possible mechanisms in perimenopausal depression, and change during adolescence in reactivity of the amygdala in relation to stressful life events and family history of depression. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a study of postpartum psychosis and mania, a home-visiting intervention for pregnant teenage American Indian mothers, brain patterns underlying learning deficits in autism spectrum disorders, the clusters of genetic variants and clinical features of schizophrenia, the Affordable Care Act and its expansion of insurance for young adults. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of hypercalcemia and hyperparathyroidism during lithium therapy. It also examines ECT for treatment-resistant bipolar depression and for clozapine-resistant schizophrenia; a weight loss intervention for individuals taking antipsychotic medications; an intervention for kindergartners with chronic conduct problems; a clinical trial offering depression care in OB-GYN clinics; and treatment response related to insurance. Articles can be viewed online at ajp.psychiatryonline.org.

This audio program includes a discussion of mercury poisoning and its neuropsychiatric presentations and presents a large study that used a new approach to testing the effect of antidepressants on heart rate. Several articles are about biomarkers of psychiatric illness: one identified a combined epigenetic and genetic biomarker for suicide, and another found that a measure of inflammation in depressed patients predicted the outcome of treatment with escitalopram and nortriptyline. Finally, a commentary on biomarkers considers how biological tests can be incorporated into psychiatric diagnostic criteria. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program explores pulmonary embolism in psychiatric patients, a trial of smoking cessation combining varenicline and bupropion, a trial comparing quetiapine with placebo for treatment of borderline personality disorder, a study of positive traits in co-twins of patients with bipolar disorder, a study evaluating the genetic and environmental contributions to familial recurrence of autism spectrum disorder, and a long-term study of the effectiveness of supported employment for persons with severe mental illness. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program explores relapse prevention in pediatric depression and the risk of mania or hypomania for patients with bipolar depression taking an antidepressant without a mood stabilizer. The series on global mental health describes a man in Cambodia with seizures, anorexia, and depression. The issue covers adverse neuropsychiatric effects of glucocorticoid medications, the patient-therapist relationship in psychotherapy, and the outcomes of psychodynamic therapy and CBT in social anxiety disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents diagnostic and treatment aspects of disruptive mood dysregulation disorder, predictors of long-term outcome in youths with bipolar disorder, reading ability and elements of impulsivity related to aggression in schizophrenia, a global health review of a woman in Uganda with HIV and major depression, and the connection between schizophrenia and maternal levels of C-reactive protein. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents a case of delirium with manic symptoms in a patient with end-stage COPD, a clinical vignette about a chronically depressed woman in Iran, low dopamine transmission in the prefrontal cortex of people with alcoholism, a test of mindfulness training as a way to increase resilience in Marines before deployment, the influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in the offspring of Holocaust survivors, and the ties between the unexpected death of a loved one and psychiatric disorders across the life span. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a new tool for screening military veterans to evaluate the risk of violence. One article reviews the care of pregnant women with ADHD, and another one reports on outcomes after in-utero exposure to lithium. Also discussed is the treatment of separation, generalized, and social anxiety disorders in children and adolescents, and two longitudinal studies shed light on the continuity of preschool depression and on adult health and functioning in people who were bullied as children. Articles can be viewed online at www.ajp.psychiatryonline.org.