December 09, 2025

Aortic Regurgitation: Beyond the Valve

21 minutes

Guest: Vidhu Anand, M.B.B.S.

Host: Kyle Klarich, M.D.

In this episode of Mayo Clinic’s “Interviews With the Experts,” Dr. Klarich and Dr. Anand discuss evolving approaches to assessing left ventricular remodeling in chronic aortic regurgitation. Dr. Vidhu Anand discusses research showing that LV volumes, global longitudinal strain, and myocardial fibrosis can detect dysfunction earlier than traditional guideline thresholds. Listeners can expect to better understand the role of multimodality imaging, extra valvular involvement, and practical steps echocardiographers can take to optimize AR assessment.

Topics Discussed:

What imaging markers help detect early myocardial dysfunction in AR, and how do they assist in risk stratification?

Guidelines traditionally focus on LV dimensions and ejection fraction for surgical decision-making in AR. Is there any data that guidelines may not be capturing patients at the optimal time?

Is there a role of multimodality imaging in AR?

What practical steps can a sonographer or echocardiographer today to bring their AR assessment closer to what your research suggests is optimal?

Please reference Dr. Anand's research article(s) here:

https://pubmed.ncbi.nlm.nih.gov/39545891/

https://pubmed.ncbi.nlm.nih.gov/33253815/

https://pubmed.ncbi.nlm.nih.gov/39218370/

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:

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No CME credit offered for this episode.

Podcast episode transcript found here.

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By Mayo Clinic

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December 09, 2025

Aortic Regurgitation: Beyond the Valve

21 minutes

Aortic Regurgitation: Beyond the Valve

Guest: Vidhu Anand, M.B.B.S.

Host: Kyle Klarich, M.D.

Topics Discussed:

What imaging markers help detect early myocardial dysfunction in AR, and how do they assist in risk stratification?

Guidelines traditionally focus on LV dimensions and ejection fraction for surgical decision-making in AR. Is there any data that guidelines may not be capturing patients at the optimal time?

Is there a role of multimodality imaging in AR?

What practical steps can a sonographer or echocardiographer today to bring their AR assessment closer to what your research suggests is optimal?

Please reference Dr. Anand's research article(s) here:

https://pubmed.ncbi.nlm.nih.gov/39545891/

https://pubmed.ncbi.nlm.nih.gov/33253815/

https://pubmed.ncbi.nlm.nih.gov/39218370/

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:

No CME credit offered for this episode.

Podcast episode transcript found here.

...more