May 20, 2025

Assessing Recurrence Following Pulsed Field Ablation for Atrial Fibrillation

10 minutes

Guest: Nicholas Tan, M.D., M.S.

Host: Anthony H. Kashou, M.D.

Pulsed field ablation has been rapidly adopted across the United States since FDA approval was granted 1 year ago, due to its excellent acute efficacy, favorable safety profile, and fast workflow. However, recurrences post-ablation are comparable to that of previously established modalities, making this a significant hurdle that has yet to be overcome. Changes to mapping/ablation strategies, updates to PFA parameters, autonomic modulation, and combination modality ablations (PFA/RFA) offer some avenues for improvement

Topics Discussed:

What is pulsed field ablation (PFA) and how does it differ from previously established modalities of ablation such as radiofrequency and cryoablation?

What are the recurrence rates post-PFA and how do they compare with other modalities?

In patients who undergo redo ablations following an index PFA procedure, what are the most common causes (i.e. reconnection of pulmonary veins versus new sites)?

How do you think PFA will evolve in the coming years

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:

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No CME credit offered for this episode.

Podcast episode transcript found here.

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By Mayo Clinic

4.5

3030 ratings

May 20, 2025

Assessing Recurrence Following Pulsed Field Ablation for Atrial Fibrillation

10 minutes

Assessing Recurrence Following Pulsed Field Ablation for Atrial Fibrillation

Guest: Nicholas Tan, M.D., M.S.

Host: Anthony H. Kashou, M.D.

Topics Discussed:

What is pulsed field ablation (PFA) and how does it differ from previously established modalities of ablation such as radiofrequency and cryoablation?

What are the recurrence rates post-PFA and how do they compare with other modalities?

In patients who undergo redo ablations following an index PFA procedure, what are the most common causes (i.e. reconnection of pulmonary veins versus new sites)?

How do you think PFA will evolve in the coming years

Connect with Mayo Clinic's Cardiovascular Continuing Medical Education online at https://cveducation.mayo.edu or on Twitter @MayoClinicCV and @MayoCVservices.

LinkedIn: Mayo Clinic Cardiovascular Services

Cardiovascular Education App:

No CME credit offered for this episode.

Podcast episode transcript found here.

...more