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Editor-in-Chief, Robert Amdur, MD, explains how radiation oncologists are using ChatGPT and other Large Language Model programs in clinical practice. The discussion is based on a paper published in the November/December 2023 issue of PRO titled "Unlocking the Power of ChatGPT, Artificial Intelligence, and Large Language Models: Practical Suggestions for Radiation Oncologists" (2023, Issue 6, November/December, PMID: 37598727).

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Dr. Sue Yom hosts Dr. Charles "Chuck" Mayo, Professor and Director of Radiation Oncology Informatics and Analytics at the University of Michigan and first author of an article in this month's issue, Operational Ontology for Oncology (O3) – A Professional Society-Based, Multi-Stakeholder, Consensus-Driven Informatics Standard Supporting Clinical and Research Use of "Real-World" Data from Patients Treated for Cancer, and Dr. Ying Xiao, Professor of Radiation Oncology at the University of Pennsylvania and supervising author of this same article, who also issued an accompanying explanatory editorial. Our group discusses the status and potential of oncology data standardization and its practical implementation through O3.

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Editor-in-Chief Dr. Sue Yom is joined this month by co-host Dr. Danielle Margalit, the Red Journal's Head and Neck Section Editor and Associate Professor of Radiation Oncology at Harvard Medical School. Guests are Dr. Adam Garden, Professor of Radiation Oncology at UT MD Anderson Cancer Center, who is the first author of an article in this month's issue, "Final Report of NRG Oncology RTOG 0022: A Phase 1/2 Study of Conformal and Intensity Modulated Radiation for Oropharyngeal Cancer"; Dr. Michelle Echevarria, Assistant Member in the Department of Radiation Oncology at Moffitt Cancer Center and first author of another article printing this month, "Phase 1 Dose Escalation of Stereotactic Body Radiation Therapy and Concurrent Cisplatin for Reirradiation of Unresectable, Recurrent Squamous Cell Carcinoma of the Head and Neck"; and Dr. Robert Chin, Associate Professor at UCLA Radiation Oncology and supervising author of a third article in the October issue, "High Recurrence for HPV-Positive Oropharyngeal Cancer With Neoadjuvant Radiation Therapy to Gross Disease Plus Immunotherapy: Analysis From a Prospective Phase Ib/II Clinical Trial."

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Practical Radiation Oncology associate editor Louis Potters, MD, of Northwell Health hosts a conversation on Treatment of Oligometastatic Non-Small Cell Lung Cancer: An ASTRO/ESTRO Clinical Practice Guideline. Two of the authors, Puneeth Iyengar MD, PhD of Memorial Sloan Kettering Cancer Center and Matthias Guckenberger MD of the University Hospital Zurich, along with patient advocate Jill Feldman discuss the framework for the treatment of oligo-mets of lung cancer.

Editor-in-Chief, Robert Amdur, MD, explains the main values used to evaluate conformality and dose gradient in treatment plans with high intensity hypofractionated dose schedules as are used in radiosurgery or stereotactic body radiotherapy. The basis for the discussion is a paper published in the September 2023 issue of PRO titled "Benchmarking Tests of Contemporary SRS Platforms: Have Technological Developments Resulted in Improved Treatment Plan Quality?" (2023, Issue 5, September/October, PMID: 37290672).

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Editor-in-Chief Dr. Sue Yom hosts a discussion this month on audiovisual technology in the service of patients, along with Pediatrics/Sarcoma Section Editor Dr. Ralph Ermoian, Associate Professor in the Department of Radiation Oncology at the University of Washington School of Medicine. Joining the discussion are Dr. Susan Hiniker, Assistant Professor of Radiation Oncology at Stanford University, who is the supervising author of an article in this month’s issue, Feasibility of the Audio-Visual Assisted Therapeutic Ambience in Radiotherapy (AVATAR) System for Anesthesia Avoidance in Pediatric Patients: A Multicenter Trial. We also welcome Dr. Jee Suk Chang, Assistant Professor at Yonsei University in Korea, currently on sabbatical at BC Cancer in Vancouver, who is (co) first author on an article in press that has just issued online, An Investigation of the Impact of Virtual Reality on Alleviating Anxiety in Patients with Breast Cancer Undergoing Radiotherapy: A Randomized Controlled Trial.

Editor-in-Chief, Robert Amdur, MD, discusses misinformation about cancer treatment. The discussion is based on a paper published in the July 2023 issue of PRO titled “Identifying Cancer Treatment Misinformation and Strategies to Mitigate Its Effects With Improved Radiation Oncologist−Patient Communication" (2023, Issue 4, July/August, PMID: 36736620).

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Editor-in-Chief Dr. Sue Yom hosts a discussion this month on the role of radiotherapy in the optimal treatment of recurrent and refractory lymphoma. Guests include Dr. Belinda Campbell, the journal’s Section Editor of lymphoma and hematologic malignancies, Honorary Clinical Associate Professor at The University of Melbourne, and Deputy Director of Radiotherapy at Peter MacCallum Cancer Centre. We are joined by Dr. Mario Levis, Assistant Professor in the Department of Oncology from the University of Turin and first author of a paper in this month’s issue, Peri-transplant radiotherapy in refractory or relapsed Hodgkin lymphoma patients undergoing autologous stem cell transplant: long term results of a retrospective study of the Fondazione Italiana Linfomi. Our other guest is Dr. Jennifer Peterson, Associate Professor in the Department of Radiation Oncology at Mayo Clinic Florida, who is the supervising author of another paper this month, Don’t put the CART before the horse: The role of radiation therapy in peri-CAR T-cell therapy for aggressive B-cell non-Hodgkin lymphoma.

Editor-in-Chief, Robert Amdur, MD, discusses RT before, rather than after, mastectomy in patients with locally advanced breast cancer being treated with neoadjuvant chemotherapy. The discussion is based on a paper published in the July 2023 issue of PRO titled “Pathologic Complete Response and Oncologic Outcomes in Locally Advanced Breast Cancers Treated With Neoadjuvant Radiation Therapy: An Australian Perspective" (2023, Issue 4, July/August, PMID: 36599393).

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Editor-in-Chief Dr. Sue Yom and Physics Section and Executive Editor Dr. David Carlson, Professor, Vice Chair, and Director of Medical Physics at Yale University, host a discussion of current research frontiers in particle therapy. Our guests (calling in from PTCOG!) are Dr. Tracy Underwood, Senior Physicist at Leo Cancer Care and one of the supervising authors of Proposing a Clinical Model for RBE Based on Proton Track-End Counts, and Dr. Andrea Mairani, Group Leader of Biophysics at Heidelberg Ion Beam Therapy Center and supervising author of Commissioning of Helium Ion Therapy and the First Patient Treatment With Active Beam Delivery.