Johann Sebastian Bach's Cello Suite No I in G major is one of the most frequently performed and recognisable solo compositions ever written for cello.

Yet it was virtually unknown for almost 200 years until the Catalan cellist, Pablo Casals discovered an edition in a thrift shop in Barcelona. Casals became the first to record it and the suites are now cherished by musicians across the globe.

The world renowned cellist, Steven Isserlis describes his relationship with the piece and why it still surprises and excites him.

Fellow cellists Richard Jenkinson and Jane Salmon talk about the challenge of playing it and we hear from the Dominic Martens, a member of the National Youth Orchestra and his teacher, Nick Jones as they explore the piece together.

Garden designer Julie Moir Messervy, describes how Yo-Yo Ma's recording inspired her to design The Toronto Music Garden and doctor Heidi Kimberly explains why she chose the piece for her wedding and why she believes the suite to have healing powers.

While historian and author, Eric Siblin, reveals the extraordinary history of the suites and why some still argue that they was written by Bach's second wife Anna Magdalena.

Series about pieces of music with a powerful emotional impact.

Producer: Lucy Lunt

First broadcast on BBC Radio 4 in April 2015.