From Disney to Microsoft, via Vodafone and Virgin Media, Cindy Rose has been a top executive at some of the world’s best known companies. Born and raised in the US, one of her early passions was figure skating – a sport she confessed left her covered in bumps and bruises. After qualifying as a lawyer, she later switched to corporate roles, relocating to Europe then London. Her time at Disney included a shift dressed as Mickey Mouse’s loyal hound, Pluto, welcoming guests to the Californian theme park. Now she’s set to become the new CEO of the troubled FTSE ad giant, WPP – where her experience in tech and AI look set to be an asset.

Presenter: Stephen Smith

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Piers Litherland has been called a modern-day Indiana Jones. He’s a former banker-turned-archaeologist who led the discovery of the lost tomb of Tutankhamun's relative, Thutmose II. As a child, Litherland was obsessed with Egypt. It was a passion that never left him, even as he pursued a career in finance. But it was only after a chance meeting with an eminent Egyptologist from Cambridge that he decided to ditch the office job and follow his heart. Since then, Litherland has headed a joint Anglo-Egyptian mission in Egypt’s Western Wadis - funding the project himself. Then, in February 2025, his team made what’s been called ‘the discovery of the century’ - the tomb of Thutmose II, an ancestor of Tutankhamun. Litherland said he cried when he realised what he'd found. Stephen Smith speaks to friends, family and colleagues of Piers Litherland, charting his life and passion that led to the discovery of the first tomb of an Egyptian King since Tutankhamun in 1922.

Presenter: Stephen Smith

Zohran Mamdani is the Democratic candidate for New Yok City mayor after a stunning victory in the primary race. If he goes on to win the mayoral election in November he will become the first Muslim and Indian American to lead the nation's largest city. His nomination came as a shock to some in the mainstream Democratic party who worry his policies are too extreme and could alienate swing voters. Before turning to politics Mr Mamdani had a brief career in the music industry. Mark Coles interviews his friends and family about his rise from rap artist to politician.

Producers: Natasha Fernandes and Ben Crighton

Production Co-ordinator: Maria Ogundele

Sound: Gareth Jones

Editor: Nick Holland

Charlie xcx is known to fans for her avant-garde, innovative approach to pop music. For many, the singer-songwriter, who’s won 5 BRIT awards and 3 Grammys, is one of the most influential figures in 21st century pop. Born Charlotte Aitchison in Cambridge in 1992 and raised in Essex, she was still at school when she began posting songs on MySpace and performing at warehouse raves, eventually landing a record deal in 2010. Her stage name, Charli xcx is a nod to her MSN screen name from when she was younger. Charli xcx first had success writing and collaborating on hits for other people. Her 2024 album, Brat, became a global pop culture phenomenon and was even embraced by US Presidential candidate, Kamala Harris, for a while. Mark Coles charts her career from wannabe teenage rave DJ to major label star.

Presenter: Mark Coles

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Current Director-General of Technology and Innovation, Blaise Metreweli, was recently appointed as the new chief of the UK’s Secret Intelligence Service, MI6. She’s the first woman to assume the role. She attended Westminster School, where she got a glimpse of leadership in her role as head girl. In 1995, she went on to study Anthropology at Cambridge University. Beyond the lecture halls, Blaise Metreweli was a keen sportswoman. In 1997, the Cambridge women's team she was in beat their rivals Oxford University in the Boat Race. After graduating, she set her sights on an international career, applying to be a diplomat but was diverted to work for MI6 instead. During her time serving as a spy, she was reportedly posted to Europe, Iraq and other parts of the Middle East.

Presenter: Stephen Smith

Actress and disability campaigner, Liz Carr, is probably best known for her role as forensic examiner, Clarissa Mullery, in the TV crime drama, Silent Witness. She’s also done comedy, theatre and even written a musical, about what she calls ‘assisted suicide’. Last year she fronted the award-winning BBC TV documentary, Better Off Dead, making the case against assisted dying.

Born and raised in Merseyside, Liz Carr became seriously ill when she was seven and has used a wheelchair since she was eleven. Whilst studying law at Nottingham University, she got involved in politics, disabled rights and activism. As her public profile grew she became a powerful voice in the debates over assisted dying.

As the assisted dying bill returns to the Commons this week, with MPs debating and voting on a series of contentious amendments, Mark Coles speaks to Liz’s friends and colleagues about her acting, comedy and campaigning.

Presenter: Mark Coles

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Donald Trump calls Susie Wiles the “ice maiden” for her ability to stay cool under pressure. It’s an invaluable skill in her role as White House Chief of Staff - responsible for who has access to the President.

Aged 68, Susie Wiles has spent more than 40 years in Republican politics – steering powerful men to elected office. She’s worked for US presidents, governors, mayors and Congress members. But she likes to stay out of the limelight.

Most of her experience has been in Florida, where she’s had a string of political success stories. Including big names like Senator Rick Scott and Ron DeSantis – running their campaigns to become governor of the Sunshine State.

Back in 2015, Donald Trump was a long shot for President, so he turned to Wiles for help winning Florida. His victory in the state helped him clinch the White House in 2016.

As Trump’s campaign manager for the 2024 run, Susie Wiles is widely credited with running what many regard as Trump’s most disciplined and strategic campaign.

Susie Wiles grew up in New Jersey. Her father, Pat Summerall, was a professional football player and later a famous sports broadcaster. But, he was an alcoholic and he credits his daughter for helping him overcome his addiction.

Stephen Smith talks to friends, colleagues and commentators to find out how events in Susie Wiles’ life have shaped her to become one of President Trump’s most trusted advisors – doing a job widely considered to be one of the most important in Washington.

Presenter: Stephen Smith

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Tom Fletcher heads the UN’s Office for the Coordination of Humanitarian Affairs (OCHA) and has been at the forefront of recent efforts to deliver aid into Gaza.

Presenter: Mark Coles

In April 2024 Rosemary Coogan became only the third person from the UK to qualify as an astronaut after completing basic training with the European Space Agency (ESA).

Originally from Northern Ireland, she excelled academically and holds two master's degrees from Durham University and a PhD in astronomy from the University of Sussex. She became an ESA astronaut after a challenging selection process which whittled down 22,000 applicants. The agency hopes to send Rosemary to the International Space Station by 2030.

In this episode of Profile, Stephen Smith explores the life and career of the woman who has a chance of becoming the first person from the UK to walk on the moon.

Presenter: Stephen Smith

Earlier this month the US Secretary of State Marco Rubio was also made President Trump's National Security Advisor. The last person to undertake both roles simultaneously was Henry Kissinger in the 1970s. The son of Cuban immigrants, Mr Rubio has had a turbo-charged career; rising from junior positions in his home city of Miami, to the US Senate which he reached before he turned 40 and now a Cabinet position where he dominate US foreign policy.

As a boy he dreamed of being President and he made his first attempt in 2016. The Republican primaries were brutal, with candidates trading deeply personal insults. It was assumed that Mr Rubio's relationship with the eventual winner of that contest - Donald Trump - had been fatally damaged. But they continued their working relationship and today Rubio serves as one of the President's most trusted advisors.

Will Marco Rubio be tempted to run once again for the White House? And what forces have shaped his stellar political career?

Presenter: Mark Coles