The Fertility Podcast

Bitesize: Why an IVF cycle doesn't work


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This episode of The Fertility Podcast Bitesize is a conversation with Dr Matt Prior, a doctor in Newcastle, and an NHS consultant one of 143 experts is answering more of your questions over at fertially.com who we've worked with to make this bitesize chunk for you. In this episode Matt explains what tests you can expect prior to starting IVF treatment, how you can prepare for your first cycle and he also explains why it might not work. Nothing can take away the heartache of a failed cycle, however hearing an expert validate that it's not your fault can sometimes ease the pain, which is why we wanted to share this bitesize snippet.

What we discussed:

  • Tests you should expect before starting treatment: 3 most important are an Ultrasound to check womb, and counting follicles, AMH to check egg reserve, Male would have a sperm test to check any issues to make sure you don’t go through collecting eggs and then there being an issue with the sperm. Other tests might check blood - for anaemia, thyroid function, also both partners would be advised to check for Hepatitis and HIV. 
  • Statistically first cycle is most likely to work, but IVF isn’t the most successful of treatment. 
  • For most people whatever age - its not likely to be successful 
  • Ahead of IVF take folic acid good, eat a sensible diet, don’t limit the amount of alcohol that you drink, look at different lifestyle factors.
  • It’s important that even if you do take into consideration a change in lifestyle factors, if your treatment doesn’t work it’s key not to beat yourself up that you  might not have stuck to the diet that google told you or the book you bought. 
  • Know that actually, most of it is out of your control and while you can do everything to try and prepare to make the IVF cycle successful, it might not happen.
  • Consider IVF as a funnel - of those starting will have an egg collection 95% or nearly all of them will have embryos to transfer. 
  • 30 to 40% of women all become pregnant
  • After a positive pregnancy test, about 70 to 80% of women go on and have a baby so really IVF fails the most between embryo transfer and pregnancy test.
  • Issues with embryo grading, putting back a perfect embryo still doesn’t guarantee success
  • Transfer process could be problematic
  • There could a problem with the womb lining - there is still a lack of evidence. 

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