The Neuro Experience

Can Alzheimer’s Be Prevented? The Role of Genetics, Hormones & Lifestyle Choices in Cognitive Health


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In this conversation with Dr. Heather Sandison, we explore what I consider to be one of medicine's most significant misunderstandings—that Alzheimer's disease, particularly in women, is an unstoppable fate. We examine the evidence behind cognitive decline, hormones, lifestyle interventions, and a framework for preventing and even reversing what was once considered irreversible.

If you're interested in making evidence-based decisions about your brain health, understanding why traditional approaches have failed, or learning about the powerful role of lifestyle interventions in cognitive function, this episode provides both the scientific rationale and actionable strategies you need.

Subscribe to The Neuroscience Experience for more conversations that challenge conventional thinking about brain health. I'm committed to bringing you insights that transform how we approach cognitive aging and performance. 

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A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts:

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Episode Timestamps: 

  •  00:00 Why Are Women More Vulnerable to Alzheimer’s?
  •  06:13 The Role of Hormone Replacement Therapy 
  • 11:24 Understanding Alzheimer’s Disease and Dementia 
  • 17:04 Alzheimer's Drugs vs. Lifestyle Interventions That Work 
  • 29:50 APOE Gene, Genetic Risk, Lipids, and Cholesterol in Alzheimer’s 
  • 37:47 How the Ketogenic Diet Impacts Brain Health 
  • 41:11 GLP-1 Agonists and Their Role in Cognitive Health 
  • 44:30 How Infections Contribute to Cognitive Decline 
  • 48:00 Plasma Exchange and Alternative Therapies 
  • 52:09 Foundational Health Practices & Dual Task Exercise 
  • 54:17 Conclusion and Further Resources 

The Neuro Athletics Newsletter
Instagram: @louisanicola_
Twitter : @louisanicola_
YouTube: @Louisa Nicola

The Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman

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The Neuro ExperienceBy Neuro Athletics

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