The Proof with Simon Hill

Can We Cure Aging?: Unpacking the Interventions | Andrew Steele, PhD


Listen Later

Episode #262. Discover the science of getting older without getting old in this conversation with Dr Andrew Steele. From understanding what impacts your lifespan to revealing potential future scientific breakthroughs, this episode is an intriguing journey into the world of aging science.


Specifically, we discuss:

  • Intro (00:00)
  • Dr. Andrew Steele on aging (01:38)
  • Age-related diseases and lifespan extension (10:47)
  • Genetic factors, lifestyle, and gene editing for longevity (19:18)
  • Could gene editing help solve poor cholesterol? (27:52)
  • Rapamycin vs metformin for longevity (34:21)
  • The need for expert consensus on anti-aging interventions (39:47)
  • Insights on Bryan Johnson's Project Blueprint (47:50)
  • What are senolytic drugs? (51:24)
  • Yamanaka factors: is aging reversible at a cellular level? (1:05:18)
  • The rationale behind reversing aging and the future of interventions (1:17:42)
  • Lifestyle changes that slow the clock (1:25:40)
  • Calorie restriction and longevity (1:32:41)
  • Air quality, smoking, and vaping (1:44:54)
  • Stress, aging, and telomeres (1:51:18)
  • Are there biological reasons why women tend to live longer? (1:59:05)
  • Unpacking the buzz around HRT for men (2:04:14)
  • Environmental impact of extending human lifespan (2:07:23)
  • Outro (2:14:10)

  • Connect with Dr Andrew Steele on TwitterInstagram, and Mastodon. Make sure to also head to his YouTube channel, where you’ll find videos on the ethics of prolonging lifespan and whether you can become biologically younger. Discover his book, “Ageless: The new science of getting older without getting old”, at https://andrewsteele.co.uk/ageless/, and read the free chapter on ethics here.

    Enjoy, friends.

    Simon


    Want to support the show?

    The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family.

    Simon Hill, MSc, BSc (Hons)

    Creator of theproof.com and host of The Proof with Simon Hill

    Author of The Proof is in the Plants

    Watch the episodes on YouTube or listen on Apple/Spotify

    Connect with me on InstagramTwitter, and Facebook

    Nourish your gut with my Plant-Based Ferments Guide

    Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

    ...more
    View all episodesView all episodes
    Download on the App Store

    The Proof with Simon HillBy Live better for longer

    • 4.9
    • 4.9
    • 4.9
    • 4.9
    • 4.9

    4.9

    2,429 ratings


    More shows like The Proof with Simon Hill

    View all
    The Rich Roll Podcast by Rich Roll

    The Rich Roll Podcast

    11,813 Listeners

    FoundMyFitness by Rhonda Patrick, Ph.D.

    FoundMyFitness

    5,292 Listeners

    Nutrition Facts with Dr. Greger by Michael Greger, M.D. FACLM

    Nutrition Facts with Dr. Greger

    3,462 Listeners

    NutritionFacts.org Video Podcast by Michael Greger, M.D. FACLM

    NutritionFacts.org Video Podcast

    846 Listeners

    The mindbodygreen Podcast by mindbodygreen

    The mindbodygreen Podcast

    2,061 Listeners

    Heart Doc VIP with Dr. Joel Kahn by Dr. Joel Kahn

    Heart Doc VIP with Dr. Joel Kahn

    471 Listeners

    The Exam Room by the Physicians Committee by Physicians Committee

    The Exam Room by the Physicians Committee

    3,339 Listeners

    Dhru Purohit Show by Dhru Purohit

    Dhru Purohit Show

    3,484 Listeners

    The Dr. Hyman Show by Dr. Mark Hyman

    The Dr. Hyman Show

    9,197 Listeners

    The Peter Attia Drive by Peter Attia, MD

    The Peter Attia Drive

    7,814 Listeners

    Switch4Good by Dotsie Bausch and Alexandra Paul

    Switch4Good

    463 Listeners

    PLANTSTRONG Podcast by Rip Esselstyn

    PLANTSTRONG Podcast

    2,289 Listeners

    Eat to Live by Jenna Fuhrman, Dr. Fuhrman

    Eat to Live

    545 Listeners

    ZOE Science & Nutrition by ZOE

    ZOE Science & Nutrition

    1,925 Listeners

    The Dr. Gabrielle Lyon Show by Dr. Gabrielle Lyon

    The Dr. Gabrielle Lyon Show

    1,106 Listeners