When strategizing how to tackle pores, the science is about as random as the skincare landscape. The chemists tackle the biology, the ingredients, and the skincare to try to make sense of what steps can actually make a meaningful difference to help reduce pore size. Can “glass”, “egg”, poreless skin actually achievable?

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the spicules deep dive, the chemists review the top two spicule (reedle) skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspectives.

Continuing our journey of diving into exciting, trendy new ingredients, this week, the chemists take a closer look at all the science behind spicule skincare. Though these prickly bits derived from marine sponges definitely have some interesting data, we still have more questions on how to best use spicules… Let’s jump in the rabbit hole!

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the PDRN deep dive, the chemists review the top two PDRN skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective.

One of the most popular requests for us to decode is PDRN. Kbeauty continues to be at the center of trendy and exotic “new” skincare. This week, the chemists’ dive into PDRN, fragmented DNA derived from salmon sperm? They discuss what it is, how it ended up in our skincare, and if there’s any substantial evidence of PDRN’s benefits for skin. Let’s go down the rabbit hole!

We’re kicking off the 2025 podcast season with a twist. With all of our new listeners and viewers, it’s time to brush up on the fundamentals of who exactly the chemists are, how we analyze the science, and just what sort of decoding you can do to assess your skincare like an expert! Think of this as a primer into all the deep dives we’ll be getting into and an episode dedicated to getting to know us and how our brains work on a deeper level. Enjoy!

It’s the last episode of 2024! Reflecting back on the year, we’re discussing top skincare science and animal fun facts. We also share our plans for the new year. The podcast has truly built an incredible community and we are so grateful to you all. Happy Holidays and we'll see you in 2025.

As a follow-up on last week’s episode on skincare for certain age groups, this week, let’s dive into estrogen-based skincare, in particular creams with estradiol or estriol. This prescription skincare realm aimed to treat peri and post-menopausal skin issues like irritation, redness, and dryness. So! Do they work? Are there other benefits beyond skin barrier care?

We all know that skin changes with father time, but how should you best skincare for your specific age? We discuss the science, what major timepoints to consider and what skincare you should be using in your teens, 20s, 30-40s, and 50s+.

Neck aging can be so difficult to address because of its complex biology. But can topicals do anything to help? Let’s take a closer look at 3 neck cream clincals done by Replenix, Skinceuticals, and Revision skincare to see if you really need a dedicated product just for your neck area.