I received a podcast review that basically said because a guest talked about chronic inflammation it was a "MAHA podcast." So I decided to go straight to one of the top inflammation researchers in the world and ask him directly: is chronic inflammation actually real, or is it pseudoscience?
My guest is Dr. David Furman, the Director of Stanford Medicine's 1000 Immunomes Project (the largest longitudinal study on aging and the immune system in the world) and an Associate Professor at the Buck Institute for Research on Aging, and his answer might surprise you. We play a game of Myth or Fact and bust some of the biggest inflammation claims all over the internet, from gluten and dairy to seed oils, and microplastics. We also get into how to actually test whether you're inflamed, the surprising link between chronic stress, depression, and your immune system, why your coffee habit might be doing you a favor, and exactly what to do about all of it if you have no money to spend.
• What the best anti-inflammatory tools and habits are
• Why 80% of people over 40 are inflamed
• The surprising foods that drive inflammation
• The inflammation-stress and inflammation-depression connection
• One free thing you can do tonight to start lowering inflammation immediately
Studies mentioned in this episode:
• iAge / Thousand Immunomes Project (inflammatory aging clock, CXCL9 biomarker): Nature Aging paper via PMC / PubMed
• Chronic inflammation in the etiology of disease across the life span (Nature Medicine, 2019 — the paper linking inflammaging to major diseases)
• NLRC4 inflammasome / caffeine study (why coffee drinkers had less inflammation): Nature Medicine, 2017
• Chronic stress / caregiver glucocorticoid resistance (the cancer-caregiver study): Miller, Chen & Cole, PNAS 2012
• 2014 depression inflammation study: Mostafavi et al., Molecular Psychiatry 2014
• Kitavans tribe free from stroke and heart disease study: PubMed / PubMed
For more from Dr. David Furman:
• https://davidfurman.com/
• https://www.buckinstitute.org/
• https://med.stanford.edu/profiles/david-furman
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The Liz Moody Podcast cover art by Zack. The Liz Moody Podcast music by Alex Ruimy.
This podcast and website represents the opinions of Liz Moody and her guests to the show. The content here should not be taken as medical advice. The content here is for information purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions.
The Liz Moody Podcast Episode 446.
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