When your skin starts changing in midlife, it is easy to assume the products that used to work suddenly stopped working. And when changing the routine does not fix it, hormones usually get the blame.

But there is another shift happening at the same time that rarely gets brought into the skin conversation: your gut. In this episode of Biohacking Beauty, we get into what starts changing in the gut through perimenopause and menopause, the surprising ways those changes can show up far beyond digestion, and why some of the health strategies women swear by before 40 may need to be reconsidered later.

Cynthia Thurlow is a nurse practitioner, host of the Everyday Wellness podcast, author of The Menopause Gut, and an international speaker with more than 25 years of experience in women’s health, metabolic health, perimenopause, menopause, and intermittent fasting.

What’s Discussed:

(04:01) The health crisis that changed the way Cynthia understood midlife health.

(19:12) The gut-hormone connection most women do not know exists.

(23:14) What changes when estrogen, immunity, and the gut start shifting together.

(29:13) The early signs that progesterone may be changing.

(35:49) What your gut may have to do with ovarian and mitochondrial aging.

(41:46) The part of longevity Cynthia thinks we are seriously underestimating.

(47:54) Why Cynthia changed her own approach to intermittent fasting after 40.

Listen to this episode of Biohacking Beauty to learn what midlife gut changes may have to do with your skin, and why the answer may go much deeper than changing your skincare routine.

Find more from Young Goose:

Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Cynthia Thurlow:

Twitter: @_CynthiaThurlow

Instagram: @cynthia_thurlow_

LinkedIn: cynthia-thurlow

YouTube: cynthiathurlow

Website: cynthiathurlow.com/

The Midlife Pause supplements: themidlifepause.com

Everyone wants skin that looks brighter, firmer, smoother, and healthier for longer.

But sometimes the thing holding your skin back is not the serum you forgot to buy. It is the blood sugar spike you keep missing, the protein you are not getting enough of, the sleep window you keep pushing, the strength training you keep delaying, or the daily stress your skin has to keep recovering from.

In this Biohacking Beauty Class episode, we are talking about the habits we actually use to support skin health outside of skincare. We get into the choices that help your skin repair better, age slower, respond better to treatments, and build the kind of foundation no product can fully replace.

What’s Discussed:

(03:10) The dessert rule that helps reduce daily sugar exposure.

(05:37) Why fiber matters beyond digestion.

(06:26) What a glucose monitor can show you about foods that look “healthy.”

(08:04) Why lifting weights can change how your skin looks over time.

(10:13) What protein and micronutrients have to do with collagen support.

(11:24) How morning sunlight, sleep, and circadian rhythm connect to skin repair.

(16:16) Where red light therapy, antioxidants, and consistency fit into the bigger skin longevity picture.

Listen to this episode of Biohacking Beauty to learn the habits we swear by when we want our skin to have more to work with than skincare alone.

And before you go, we have a little listener bonus.

If you want to receive a product on us, leave us a review on Apple Podcasts. That is all you have to do.

If we read your review out loud on the podcast, we will send you a product in the mail. So leave us a review, make it cute, make it honest, and you might hear it in an upcoming Biohacking Beauty Class episode.

Find more from Young Goose:

Website: Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Thyroid dysfunction is often treated like it is easy to rule out. You ask for labs, your doctor checks TSH, and if that one marker is not flagged, you are told your thyroid is fine.

But what if that is the problem?

In this episode of Biohacking Beauty, we sit down with Dr. Amie Hornaman to unpack what most thyroid conversations skip: the difference between being “normal” on paper and having enough active thyroid hormone available to your cells. She explains why TSH is not a thyroid hormone, why T4-only medication may not be enough for many people, and why women can keep struggling even after being told their thyroid is not the issue.

Dr. Amie is known as The Thyroid Fixer, a functional medicine doctor, host of The Thyroid (and Hormone) Fixer podcast, founder of the Advanced Thyroid and Hormone Clinic, and author of The Thyroid Fix. After being misdiagnosed by six different doctors, she built her practice around helping patients get the answers conventional medicine often misses.

What’s Discussed:

(01:22) Why so many women feel like their body is rebelling against them.

(04:32) Why the diagnosed hypothyroidism number may not reflect the real problem.

(07:11) The difference between being undiagnosed, undertreated, and mistreated.

(10:54) Why skin aging after 40 is not only an estrogen conversation.

(14:22) How quickly thyroid and hormone changes can show up in the skin.

(20:57) Why skin aging needs an inside-out and outside-in approach.

(28:35) What markers belong on a full thyroid panel beyond TSH.

(30:55) Why free T3, reverse T3, and thyroid antibodies matter.

(38:48) What thyropause is and why it can overlap with perimenopause and menopause.

(45:01) A one-morning plan to support thyroid, insulin, protein, sleep, and skin health.

Listen to this episode of Biohacking Beauty to understand why your thyroid labs may not be telling the whole story, and why your skin, hair, metabolism, mood, and energy may be showing what one marker missed.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Dr. Amie Hornaman:

Website: dramie.com

Instagram: @dramiehornaman

Podcast: dramie.com/podcast/

Exosomes have become one of the most talked-about ingredients in advanced skincare, but the conversation around them can get confusing fast. Some people hear “cellular messaging” and worry about DNA. Others see plant exosomes, stem cell claims, growth factors, or vampire facial comparisons and assume all exosome products are working the same way.

The problem is that the word “exosome” does not tell you enough. Exosomes are messengers, and the message depends on the source. A plant-derived exosome, a mesenchymal-derived exosome, and a platelet-derived exosome are not carrying the same type of signal for the skin. So before you trust the trend, it helps to understand what kind of message your skin is actually receiving.

In this Biohacking Beauty Q&A, we break down the biggest questions listeners have been asking about exosomes. We get into why exosomes do not change your DNA, what microRNA messaging means, why consistency matters, how plant exosomes compare to human-derived options, why platelet-derived exosomes may be especially relevant for skin repair, and what makes Vampire Exosomes® different from other exosome serums.

What’s Discussed:

03:05 Whether exosomes can change your DNA or transfer genetic material.

07:08 How exosomes work through microRNA messaging instead of changing your genome.

09:21 Why exosome messages do not stick around forever and need consistency.

11:02 Where exosomes come from and why the source of the message matters.

13:45 Why plant exosomes may offer some benefits, but may not be the strongest fit for skin repair.

21:34 How mesenchymal-derived and platelet-derived exosomes differ in their relationship to skin repair.

27:29 What makes Vampire Exosomes® different from other exosome serums, including dose, NAD support, barrier support, and batch verification.

32:25 How Vampire Exosomes® compares to a vampire facial and why topical exosomes work differently.

Listen to this episode of Biohacking Beauty to understand what exosomes actually are, what questions to ask before buying an exosome product, and why the source, dose, formula, and proof matter as much as the word “exosome” itself.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Young Goose Vampire Exosomes® https://www.younggoose.com/products/vampire-exosomes

Instagram: @young_goose_skincare

A lot of beauty treatments are sold around the result people want most: tighter skin, fewer lines, more volume, and a face that looks refreshed without going under the knife.

And because these treatments have become so common, it can feel like the decision is simply about when to start, who to go to, or which device or injectable will give the most natural-looking result.

But Anastasia looks at the face through a different lens. In Part 2 of this conversation, she challenges the idea that a visible result is the only thing worth paying attention to. She brings the conversation back to the tissue underneath the skin, the movement of the face, how the body responds, and what people may want to question before choosing treatments that promise to tighten, fill, freeze, or stimulate the face.

What’s Discussed:

35:15 Why tightening devices are often positioned as an alternative to plastic surgery.

36:55 What people may want to consider before choosing treatments that rely on stimulation or controlled damage.

41:51 Why the risks of beauty shortcuts are not always obvious at first.

45:24 What to know about training, devices, and the person performing the treatment.

51:15 What Anastasia wants people to think about before getting fillers.

53:53 Why the body’s response to fillers deserves more attention.

1:02:47 Why preventative Botox deserves a deeper conversation than wrinkle prevention.

1:12:21 Where Anastasia lands on sun exposure, SPF, and skin protection.

1:19:43 What she wants women to start questioning about beauty, aging, and the tissue underneath the skin.

Before choosing the next treatment that promises to lift, tighten, smooth, or freeze time, this conversation asks you to slow down and look at what may be happening beneath the result.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Anastasia:

Website: BeautyFascia.com/

Instagram: @anastasiabeautyfascia

Red light masks, facial sculpting devices, gua sha tools, and at-home lifting treatments are everywhere. And when a tool promises less puffiness, a sharper jawline, or younger-looking skin, it is easy to believe the right device could finally create the change you have been looking for.

But a face is not a collection of surface-level problems. The way it looks and ages is also influenced by muscle tension, facial structure, breathing patterns, soft tissue, posture, and how fluid moves through the tissue. So when a beauty tool does not create the result you expected, the problem may be that the tool was never addressing what was actually driving the change.

Anastasia, a board-certified Structural Integration Therapist and founder of Beauty Fascia, returns to explain what she looks at beyond skin appearance and what some of the biggest at-home beauty trends can realistically do. She shares why she prefers a red light panel over a mask, where facial devices may fall short, when gua sha can help, and why doing more is not always better for the skin.

What’s Discussed:

03:13 What Anastasia looks at beyond wrinkles and skin appearance.

04:35 How facial structure, muscle tension, breathing, and fluid flow influence the way the face looks.

09:02 Why Anastasia prefers a red light panel over a mask.

10:04 What to consider before spending money on a red light device.

17:54 Why buying a beauty tool does not automatically create a self-care habit.

23:56 What at-home facial devices can realistically change.

28:48 When gua sha may help, why under-eye bags are not always a lymphatic problem, and how overdoing it can backfire.

Before investing in another device or adding another technique to your routine, it helps to know what problem you are actually trying to solve and whether the tool was designed to address it.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Anastasia:

Website: BeautyFascia.com/

Instagram: @anastasiabeautyfascia

Skincare trends are moving fast, and it can be hard to tell what is actually worth your attention. One day everyone is talking about red light masks, then peptide lip balms, at-home microneedling, men’s skincare, acne protocols, or another product claiming to be the next thing your skin needs.

The problem is that some of these tools can be useful, but the way they are marketed often leaves out the context that matters most. A red light device is not just about wavelength. Acne is not just about bacteria. Peptides in skincare are not automatically effective just because the word is on the label. And not every trend deserves to become the center of your routine.

In this Q&A episode of Biohacking Beauty, we’re answering the skincare questions you sent in and breaking down what to look at before buying into the hype. We get into acne, red light therapy masks, at-home microneedling, men’s skincare, and the peptide skincare problem so you can think about these trends with more science and less noise.

What’s Discussed:

(03:14) Why acne is not just a bacteria problem.

(07:24) What to know before buying a red light therapy mask.

(13:36) The red light devices we actually use at home.

(16:06) At-home microneedling, skin barrier risk, and where to draw the line.

(21:02) Why men’s skincare is mostly marketing.

(25:10) What performance skincare may actually mean.

(29:41) Why peptide skincare claims are harder to verify than they seem.

Listen to this episode of Biohacking Beauty to understand which skincare trends deserve a closer look, what questions to ask before buying, and where the science matters more than the marketing.

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Peptides are being treated like the missing piece in recovery, skin longevity, fat loss, performance, and aging. The usual belief is that if you find the right compound, the right dose, or the right stack, the body will finally respond the way you want it to. But what if the protocol is not the first thing that needs to be fixed?

In this episode of Biohacking Beauty, I sit down with Chris Duffin to unpack what most peptide conversations skip: the state of the body receiving the signal. They get into why cellular terrain matters, what happens when people chase regenerative tools before the foundation is ready, and how skin can reveal whether the body is actually prepared to adapt, repair, and age well.

Chris Duffin is the Human Performance Expert, an internationally recognized authority in human performance science, and the first person in history to squat and deadlift over 1,000 pounds for multiple reps. His work sits at the intersection of strength, resilience, peptide science, executive performance, and regenerative health, which makes this conversation a rare look at what it actually takes to build a body that can respond to advanced tools instead of just relying on them.

What’s Discussed:

(02:15) Why peptides are powerful, but not the whole answer.

(05:12) What cellular terrain has to do with regeneration.

(09:18) Why looking healthy does not always mean the body is resilient.

(15:07) How peptides fit into a bigger recovery and longevity strategy.

(27:09) What peptide reactions may reveal about the body underneath.

(50:06) Why skin rejuvenation depends on the body’s ability to respond.

(01:06:05) How peptide hype is changing the longevity conversation.

Listen to this episode of Biohacking Beauty to understand what needs to happen inside the body before peptides, procedures, or any regenerative tool can actually move the needle.

Resources Mentioned:

Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Chris Duffin:

Instagram: @mad_scientist_duffin

Website: enhancedexecutive.com/

If you have been thinking about buying a LED mask, the hardest part is knowing what actually matters. The price range is all over the place, every brand seems to have some version of “FDA cleared” on the page, and a lot of the buying advice sounds scientific enough to trust. But none of that automatically tells you whether the device is strong enough to do anything meaningful for your skin.

That is why we wanted to take a closer look at an Allure post called So You Wanna Buy a LED Mask. The guide brings up the same things people usually look at before buying one: price, number of bulbs, FDA clearance, clinical trials, and how often you have to use it. Some of those details can be useful, but they can also distract from the real questions: how much light does the device actually deliver, what wavelengths does it use, and is the coverage strong enough to create meaningful stimulation?

That matters if you are about to spend a few hundred dollars on a device and you are using the wrong signals to decide. A high price, FDA clearance, or a small clinical study can make a mask sound more credible, but those details do not always answer the question you actually care about: Will this device give my skin enough stimulation to be worth using?

What’s Discussed:

(04:22) Why we are reacting to Allure’s LED mask buying guide.

(05:12) Why the $100 to $1000 LED mask price range is not very helpful.

(07:31) Why diode count matters, but output matters more.

(08:33) Whether you actually need to use a LED mask every day.

(10:55) What FDA clearance does and does not tell you.

(13:35) Why a five-subject clinical trial is not strong proof.

(15:45) The wavelengths that matter for red light therapy.

Listen to this episode of Biohacking Beauty to understand what actually matters before buying a LED mask, and why the most scientific-sounding claims are not always the ones that tell you if a device will work.

Resources Mentioned:

Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

We have been getting the same question in our DMs for months now. Peptides are everywhere. Everyone is talking about them. But what actually has evidence behind it, what is hype, and where do hormones fit into all of this? So we went and found someone who has been living this conversation for 35 years, not just talking about it.

Dr. Jennifer Berman is a urologist, New York Times bestselling author, and one of the leading voices in female sexual and menopausal health. She pioneered the field at UCLA, runs the Berman Women's Wellness Center in Beverly Hills, and has been her own first patient through every transition she now treats. She is the kind of doctor who was doing things a decade before they became mainstream and has the clinical receipts to back all of it up.

In this episode we get into why peptides are the missing piece of the menopause puzzle, what hormones are really doing to your skin from the inside out, and how treatments that were written off as fringe became the new gold standard for longevity.

What's Discussed:

(01:42) Why peptide production declines with age and what that actually means for how women look and feel in perimenopause.

(04:04) The regulatory reality around peptides right now and why medical grade from a 503B pharmacy is the only route worth taking.

(06:07) The specific peptides with the strongest evidence for skin, muscle, fat loss, recovery, and cognitive function.

(13:12) Why your mid to late 30s is already perimenopausal by definition and why that changes when you start.

(15:02) C-Link, C-Max, and PE22-28 for mood, neuroplasticity, and cognitive protection and why Dr. Berman stacks them together.

(39:17) The exact point where topical skincare stops being enough and what hormone imbalance is doing to skin that no cream can fix.

(53:08) Why cycling your peptides matters, what receptor attenuation actually is, and why the protocol on your feed is not a clinical protocol.

By the end of this episode you will know which peptides have actual evidence behind them, where topical skincare stops working without hormonal support, and what an inside-out longevity protocol looks like from a doctor who has lived every transition she treats.

Resources Mentioned:

Age-Associated Changes in Oxidative Stress and NAD+ Study: journals.plos.org/plosone/article/

FASEB study on how methylene blue delays cellular senescence cells: faseb.onlinelibrary.wiley.com/doi/

Find more from Young Goose:

Use code PODCAST10 to get 10% OFF your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% OFF at younggoose.com

Instagram: @young_goose_skincare

Find more from Dr. Jennifer Berman:

Website: bermansexualhealth.com/

Instagram: @jenbermanmd