Biohacking Beauty: The Anti-Aging Skincare Podcast

Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications.

We dive deeper into this in the Biohacking Beauty Podcast with Alex Tarnava. We discuss why topical hydrogen is gaining attention for skin outcomes, how gut-mediated signaling may drive systemic effects, and why interpreting evidence requires understanding study design, delivery method, and real-world product variability.

WHAT’S DISCUSSED:

(04:52) Why hydrogen is not a traditional antioxidant and what that actually means biologically

(06:17) How different delivery routes change tissue targeting and systemic signaling

(10:09) Why skin aging and inflammatory conditions behave more like a systems problem than a single pathway

(15:10) How mild oxidative stress can activate endogenous antioxidant production

(16:05) The hidden risk of reductive stress from excessive antioxidant use

(17:59) Why inflammation must be regulated rather than suppressed for long-term tissue repair

(28:52) The gut-driven mechanisms that may influence visible skin outcomes

(29:42) How corporate-owned research and investigator-led studies shape the hydrogen evidence landscape

(37:25) Why exaggerated longevity claims distort innovation and erode trust

(50:49) The growing issue of counterfeit hydrogen products and what it signals about market maturity

Find more from Young Goose:

1. The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
2. Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
3. Instagram: @young_goose_skincare

Find more from Alex Tarnava:

Website: https://hydrogenwatertablets.com

https://alextarnava.com

Instagram: https://www.instagram.com/alextarnava

Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear.

We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity.

Dr. Scott Sherr is a board-certified internal medicine physician certified in Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy. He is the COO of Troscriptions and focuses clinically on mitochondrial health, stress physiology, and advanced recovery protocols.

What's Discussed:

1. (01:52) Why chronic stress is not just mental and directly impacts cellular energy
2. (05:17) How modern life keeps the nervous system stuck in chronic fight or flight
3. (07:25) Cortisol and stress hormones disrupting mitochondria and accelerating skin aging
4. (11:16) Why skin aging is often the first visible sign of mitochondrial decline
5. (24:16) The sympathetic spiral of doom explained through energy loss and stress signaling
6. (27:14) Why stress reduction and mitochondrial support must happen at the same time
7. (46:22) Why aggressive skincare and biohacking fail without mitochondrial resilience
8. (50:35) Hyperbaric oxygen therapy, sequencing, and why timing matters more than intensity

Find more from Young Goose:

1. The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
2. The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
3. VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
4. Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
5. Instagram: @young_goose_skincare

Find more from Dr. Scott Sherr:

Website: https://troscriptions.com

LinkedIn: @troscriptions

Instagram: @drscottsherr @troscriptions

Facebook: @Troscriptions

Youtube: @troscriptions

Tiktok: @troscriptions

Fascia is one of the most overlooked conversations in skin aging. We spend so much time thinking about collagen, serums, injectables, and trending tools, but very few people are talking about the structural system underneath the skin that influences how we actually age.

If you are dealing with under-eye puffiness, jaw tension, posture changes, facial asymmetry, or feeling like your face looks more tired than it should, this episode explores a deeper layer of the conversation. We dive into fascia, fluid movement, breathing patterns, and why your neck and jaw may be playing a much bigger role in your appearance than you realize.

In this conversation, we break down what fascia really is in simple terms and how it connects to collagen production, lymphatic drainage, nervous system regulation, and facial structure over time.

Anastasia is a board-certified Structural Integration Therapist trained in kinesiology, facial muscle neuro rehabilitation, neurovascular release, myofascial release, traditional Chinese medicine, and acupressure. Over the past five years, she has pursued global mentorships and seminars focused on structural and facial regeneration, bringing together multiple disciplines to support facial health, tissue quality, and overall structural balance.

To watch this episode on Youtube click here: https://youtu.be/KRs4dlmfj8s

What's Discussed:

1. (11:41) Why facial massage does not stretch skin and how tissue actually adapts
2. (19:38) Under eye puffiness as a drainage issue, not a skin problem
3. (23:12) Collagen cross linking and why fibroblasts avoid rebuilding on damaged matrix
4. (27:23) Glymphatic dysfunction and how poor brain drainage shows up in the face
5. (51:52) What happens to circulation and lymphatic flow when muscles are paralyzed with Botox
6. (53:52) Why mewing fails without addressing neck tension and structural foundation
7. (01:12:23) Phone posture, forward head position, and structural facial aging
8. (01:14:39) Aging as a structural shift before wrinkles ever appear

Find more from Young Goose:

1. The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
2. The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
3. VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
4. Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
5. Instagram: @young_goose_skincare

Find more from Anastasia (Beauty Fascia):

1. Website: https://anastasia.beauty
2. Instagram: @anastasiabeautyfascia
3. Youtube: @anastasiabeautyfascia
4. TikTok: @anastasiabeautyfascia

Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.

In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing like DEXA scans can reveal hidden bone loss long before standard guidelines would ever check.

Dr. Jila Senemar is a board-certified OB/GYN with more than 20 years of clinical experience. She is a menopause specialist certified by The Menopause Society and a longevity physician. Her clinical work focuses on perimenopause, menopause, hormone therapy, and midlife women’s health.

What's Discussed:

• (02:57) Insulin resistance as an early midlife driver of inflammation and weight gain
• (03:35) Why more cardio and restriction can worsen midlife metabolic dysfunction
• (07:27) Regular periods and no hot flashes still align with early perimenopause
• (09:44) Night waking and unrefreshing sleep as overlooked perimenopause symptoms
• (15:01) Strength training as a metabolic and hormonal support tool in midlife
• (24:40) Using DEXA scans at 40 to detect early bone density loss
• (26:15) Hormone therapy framed around longevity, not just symptom relief
• (41:14) Progesterone’s role in sleep, mood stability, and early perimenopause support

Find more from Young Goose:

• The Elastin Action Protocol →  Engineered for Skin Navigating Elasticity Change 
• The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter 
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
• Instagram: @young_goose_skincare

Find more from Dr. Jila Senemar MD, FACOG, MSCP:

• Website: https://www.jilamd.com
• Instagram: @drjilasenemar

Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.

We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the cell.

Jessica Kane is the Co-Owner and Chief Marketing Officer of BodyBio, a third-generation wellness company specializing in cellular health. She works alongside healthcare practitioners and researchers to translate complex cell membrane and lipid science into practical, evidence-based solutions. 

What's Discussed:

• (06:17) Why advanced skincare and red light therapy still fail without cellular building blocks
• (07:37) How low-fat nutrition and missing lipids weaken skin structure over time
• (09:55) Cell membranes explained as the foundation of skin barrier, tone, and elasticity
• (10:46) How phospholipids act as the “cement” between skin cells and prevent laxity
• (13:15) Why the omega-6 to omega-3 ratio matters more than taking fish oil alone
• (15:57) Why most phosphatidylcholine on the market is not truly liposomal
• (18:28) How “liposomal” labeling works and why most supplements fail cellular delivery
• (36:01) Why vitamin C and glutathione don’t impact collagen without proper absorption

Find more from Young Goose:

• Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landing
• Find our Winter Protocol here: https://younggoose.com/pages/winter-protocol
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomes
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com/?utm_source=podcast&utm_medium=apple
• Instagram: http://instagram.com/young_goose_skincare

Find more from Jess Kane: 

• Website: https://bodybio.com/
• Instagram: https://instagram.com/jesskane
• Instagram: https://www.instagram.com/bodybio/
• Tiktok: https://tiktok.com/@jesskaneb

It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.

In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives through the lens of cellular energy, inflammation control, repair, and long-term resilience.

If you’re listening on Valentine’s Day, we’re honored you’re spending it with us. And if you’re tuning in any other day, we’re just as glad you’re here. Either way, this conversation is about care that lasts and the small, intentional choices that add up over time.

What's Discussed:

• (03:38) Why this Valentine’s episode feels different as co-founders and life partners
• (06:11) Recommending ingredients based on real-time skin needs, not bias
• (12:38) Methylene blue, red light synergy, and mitochondrial skin energy
• (17:04) NAD support as the currency behind repair and long-term resilience
• (20:49) Ectoin, deep hydration, and protection from blue light and pollution
• (25:10) Retinol results, limitations, and why peptide alternatives matter
• (27:36) Sun exposure, oxidative stress, and the missing piece of post-UV DNA repair

Find more from Young Goose:

• The Elastin Action Protocol →  Engineered for Skin Navigating Elasticity Change 
• The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter 
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
• Instagram: @young_goose_skincare

Skin problems are often the body’s earliest warning sign that detoxification, inflammation control, and nutrient absorption are already compromised. When detox demand rises and recovery systems can’t keep up, skin changes and aging-related signs become more pronounced.

In this episode of the Biohacking Beauty Podcast, we sit down with Marina Moiseyeva to explore why medications and aggressive topicals increase detox load, how sweating and lymphatic movement support skin longevity, and why “Ozempic face” is driven by muscle, bone, and nutrient loss rather than fat alone.

Marina Moiseyeva is a Functional Medicine Practitioner and Board Certified Family Nurse Practitioner with 16 years of clinical experience. She is a Certified Diplomate in Anti-Aging and Regenerative Medicine, a member of the American Academy of Anti-Aging Medicine, and the author of Harmonious Healing Blueprint: Biohacking, Regeneration & Health Resilience.

What's Discussed:

• (00:00) Why skin functions as a detox organ
• (07:03) How topical treatments and medications quietly increase the body’s detox burden
• (11:34) Sweating, hydration, and lymphatic movement as primary detox pathways
• (19:32) GLP-1s, nutrient absorption, and the real mechanism behind “Ozempic face”
• (26:09) Bone density, muscle loss, and why structural facial aging is hard to reverse
• (54:48) What ages skin faster than sun exposure and why sugar-driven inflammation matters

Find more from Young Goose:

• Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landing
• Find our Winter Protocol here: https://younggoose.com/pages/winter-protocol
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomes
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at younggoose.com
• Instagram: @young_goose_skincare

Find more from Marina Moiseyeva:

• Website: https://liveharmoniouslife.com
• Instagram: @liveharmoniouslife 

Books' Amazon page links here:

• Hardcover: https://a.co/d/asQyFGW
• Paperback: https://a.co/d/gRQhEWE

Advanced skin treatments often underperform for a reason rarely addressed: regeneration cannot occur in a chronically stressed or under-resourced system. Elevated cortisol, inflammation, and metabolic imbalance weaken collagen signaling and tissue repair before any device, injectable, or modality has a chance to work.

In this episode of the Biohacking Beauty Podcast, we sit down with Joe Radich from R3 Health to unpack why physiological preparation determines treatment outcomes. 

We explore how internal factors like stress, hormones, micronutrients, and metabolic health shape skin regeneration, and why modalities like peptides, hyperbaric oxygen, and exosomes only work as well as the system they’re introduced into.

Joe Radich is an NCCPA board-certified Physician Assistant specializing in regenerative medicine and the founder of R3 Health. He trains physicians and mid-level practitioners in stem cells, PRP, exosomes, and biohacking-based clinical protocols, with expertise spanning orthopedic, aesthetic, hair restoration, and regenerative applications.

What's Discussed:

(06:42) Why chronic stress and cortisol are silent drivers of visible skin aging

(10:18) Preparing the body before skin treatments and why physiology determines outcomes

(14:07) Why microneedling success depends on internal biology, not just technique

(18:55) The most common lab patterns behind poor skin regeneration and chronic inflammation

(24:31) Hormonal imbalance vs hormone deficiency and how both affect skin aging

(33:41) GHK-Cu and peptides as signaling tools for connective tissue regeneration

(38:09) Hyperbaric oxygen as a force multiplier for skin repair, recovery, and longevity

(44:06) Exosomes and regenerative biologics and why sourcing and quality determine results

Find more from Young Goose:

• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire Exosomes
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    
• Instagram: @young_goose_skincare
• Winter Skincare Protocol: https://www.younggoose.com/pages/winter-protocol

Find more from Joe Radich (R3 Health):

Website: https://josephradich.com, https://r3health.co

Instagram: @joeradich_

Skin sagging, crepiness, and loss of bounce are often blamed on collagen loss, yet the real driver sits elsewhere in the skin’s architecture. Elastin degradation accumulates quietly over time, shaping how skin functions long before changes fully register in the mirror.

In this Biohacking Beauty episode, we unpack why rebuilding elastin is largely a myth, how elastin breakdown differs fundamentally from collagen loss, and how even a single period of stress can influence skin integrity for decades.

We also examine how collagen is over-credited in conversations about sagging and how lasers and radiofrequency treatments can create temporary tightening while promoting long-term fibrotic remodeling that undermines true elasticity. Tune in.

What's Discussed:

(05:58) Why Elastin, Not Collagen, Drives Skin Bounce and Elastic Recovery

(07:54) Elastin’s 70-Year Half-Life and Why Skin Aging Is Mostly About Preservation

(11:39) Why Rebuilding Elastin Is Largely a Myth After Puberty

(21:10) Why Collagen Loss Is Over-Credited in Skin Sagging

(23:12) Lasers, RF and Fibrotic Remodeling vs True Skin Elasticity

(26:50) The Elastin Enemies: UV, Oxidative Stress, Glycation and Inflammation

(31:39) Preservation Over Correction: Building a Daily Elastin-Protective Strategy

(34:01) Signal-Based Remodeling: Supporting Elastic Function Without Chronic Inflammation

Find more from Young Goose:

• VAMPIRE EXOSOMES: Professional Exosome Serum for Regeneration and Post-Treatment Recovery
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    
• Instagram: @young_goose_skincare
• Find our Winter Protocol here: https://www.younggoose.com/pages/winter-protocol
• Find our Elastin Action Protocol here: https://www.younggoose.com/pages/elastin-action-protocol-landing

Most conversations about advanced skin treatments stay at the surface, particularly around regenerative approaches, overlooking why lasting results are so hard to achieve.

We dive deeper into this in the latest Biohacking Beauty episode with Dylan Gemelli. We explore why oral peptides often fall short, and how BPC-157 relates to gut healing, inflammation resolution, and collagen repair. We also unpack the real mechanism behind PRP facials, and how neuromodulating peptides compare to Botox over the long term.

Dylan Gemelli is a prominent figure in the fitness and biohacking space and the host of the Dylan Gemelli Podcast. He is currently completing a master’s degree in dietetics and holds certifications as an integrative health professional and cellular health advisor, with his work centered on educating audiences about peptides, longevity, cellular health, nutrition, and neuroscience.

What's Discussed:

• (09:07) The real risks of peptides, lack of regulation, and why quality matters
• (25:56) BPC-157 beyond athletics: gut healing, inflammation resolution, and collagen repair
• (29:44) Why injectable peptides outperform oral and one-off aesthetic treatments
• (32:51) Why consistency and loading phases determine peptide results
• (37:00) GHK-Cu and why copper peptides matter for skin, hair, and tissue repair
• (46:32) Neuromodulating peptides vs Botox and long-term wrinkle prevention
• (51:21) PRP facials work because of exosomes, not needles

Find more from Young Goose:

• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery → Vampire Exosomes
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at www.younggoose.com    
• Instagram: @young_goose_skincare
• Find out everything you need to know about our Winter Protocol here: https://www.younggoose.com/pages/winter-protocol 

Find more from Dylan Gemelli:

Website: www.dylangemelli.com

Instagram: @dylangemelli