"Mister Niceguy No More" has written to Ralph about difficulties in his eleven-year marriage, describing his wife's distant and transactional approach to their sex life. This has caused him frustration and feelings of isolation. Ralph examines possible causes such as mental and hormonal health issues and suggests that proactive actions should be taken. Emphasizing the need for personal well-being and establishing boundaries, Ralph discusses how to deal with relationship problems and the importance of seeking assistance.