This Week in Startups

DeepSeek Rattles Markets + SailPoint's Going Public… again? | E2077


Listen Later

Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity’s “buy, fix, and flip” strategy? Don’t miss this deep dive into the latest tech and startup news!

*

Timestamps:

(0:00) Jason and Alex kick off the show.

(1:58) DeepSeek's market impact and Project Stargate
(4:18) Innovation, H100 GPUs, and open-source AI models
(8:41) Jevons paradox, Pat Gelsinger's analogy, and AI efficiency

(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today.

(13:25) AI's benefits for startups and privacy concerns
(19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST
(19:51) AI optimization vs. hardware consumption

(22:20) OpenAI's revenue, valuation, and NVIDIA's market value

(30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist
(33:21) Unified AI digital assistants and DeepSeq's new model
(35:01) AI's role in venture capital and team size reduction
(41:04) China's influence and DeepSeek's market impact
(43:22) Startup shutdowns and potential for increased M&A activity
(53:02) Nvidia's historical analysis, risks of leverage, and SailPoint's IPO

*

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

*

Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

*

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

*

Thank you to our partners:

(10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today.

(19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST
(30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist
*

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

*

Check out Jason’s suite of newsletters: https://substack.com/@calacanis

*

Follow TWiST:

Twitter: https://twitter.com/TWiStartups

YouTube: https://www.youtube.com/thisweekin

Instagram: https://www.instagram.com/thisweekinstartups

TikTok: https://www.tiktok.com/@thisweekinstartups

Substack: https://twistartups.substack.com

*

Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916





...more
View all episodesView all episodes
Download on the App Store

This Week in StartupsBy Jason Calacanis

  • 4.2
  • 4.2
  • 4.2
  • 4.2
  • 4.2

4.2

1,274 ratings


More shows like This Week in Startups

View all
The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch by Harry Stebbings

The Twenty Minute VC (20VC): Venture Capital | Startup Funding | The Pitch

536 Listeners

The a16z Show by Andreessen Horowitz

The a16z Show

1,105 Listeners

Invest Like the Best with Patrick O'Shaughnessy by Colossus | Investing & Business Podcasts

Invest Like the Best with Patrick O'Shaughnessy

2,342 Listeners

Founders by David Senra

Founders

2,221 Listeners

Masters of Scale by WaitWhat

Masters of Scale

3,992 Listeners

Y Combinator Startup Podcast by Y Combinator

Y Combinator Startup Podcast

233 Listeners

All-In with Chamath, Jason, Sacks & Friedberg by All-In Podcast, LLC

All-In with Chamath, Jason, Sacks & Friedberg

10,254 Listeners

Dwarkesh Podcast by Dwarkesh Patel

Dwarkesh Podcast

551 Listeners

Joe Lonsdale: American Optimist by Joe Lonsdale

Joe Lonsdale: American Optimist

171 Listeners

ACQ2 by Acquired by Ben Gilbert and David Rosenthal

ACQ2 by Acquired

300 Listeners

No Priors: Artificial Intelligence | Technology | Startups by Conviction

No Priors: Artificial Intelligence | Technology | Startups

150 Listeners

BG2Pod with Brad Gerstner and Bill Gurley by BG2Pod

BG2Pod with Brad Gerstner and Bill Gurley

475 Listeners

AI + a16z by a16z

AI + a16z

34 Listeners

TBPN by John Coogan & Jordi Hays

TBPN

140 Listeners

Uncapped with Jack Altman by Alt Capital

Uncapped with Jack Altman

42 Listeners