Kirsty Young's castaway this week the cartoonist, writer and illustrator Posy Simmonds. Her social observation and sharp wit gained a loyal following in The Guardian where - among their stripped pine, lentils and patchwork - she depicted the lives of prototype woolly liberals Wendy and George Weber. Since then she's gone on to create highly acclaimed children's books and also graphic novels Gemma Bovary and Tamara Drew.

Posy says she started drawing as soon as she could pick up a pencil and as a child was making magazines and little comics with titles like How to Turn Yourself Into an Up-to-Date Ted and How to Make Love and Be Loved in Four Easy Lessons. She remembers drawing as the perfect thing to do, because she could sit on her own and talk to herself.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: The opening of the prelude from Cello Suite No 1 in G Major by Johann Sebastian Bach

Kirsty Young's castaway this week is the pioneering surgeon Professor Ara Darzi. He was born in Iraq and brought up in Baghdad but he moved to Ireland when he was 17 to study medicine. He came to England to finish his training and, highly talented and ambitious, was made a consultant when he was barely out of his 20s. Since then he's been nick-named 'Robo-doc' for spearheading the use of keyhole surgery in Britain and for introducing robotics to the operating theatre.

For the past year he has combined his surgical work with a position in government - he is a health minister and, on the eve of the NHS's 60th birthday, he is charged with reshaping the NHS in England. It is, he says, the greatest challenge he has yet faced.

Favourite track: Seven Seconds by Youssou N’Dour and Neneh Cherry

Kirsty Young's castaway this week is the author Peter Carey. He says he grew up in his homeland "thinking that Australian history was dull and Australian literature was dull" and that he developed a strong passion to make it new and fresh. In this he has surely succeeded - he is one of only two novelists to have been awarded the Booker Prize twice.

Yet he came to writing relatively late. The son of a car salesman he started off studying science but he abandoned his university career and ended up, in his 20s, drifting into advertising. It was only then that his literary awakening began. "I announced with great confidence one day, 'I’m going to be a writer',' he says, 'I’m an obsessive fool, I was determined to do it!"

Favourite track: The Hallelujah Chorus from Messiah by George Frideric Handel

Kirsty's castaway this week is the comedian and actor, Bill Bailey. Lauded for his hugely inventive stand up, he has carved out a highly successful career with an altogether atypical approach. He's a familiar face on television from his regular appearances on quiz shows Have I Got News for You, QI and Never Mind the Buzzcocks.

At school he was a gifted pupil who gave up on his education and a pitch-perfect piano student who flunked his music school entrance. He started drifting as a teenager and gave up on university within days of arrival - he says he was looking for the next challenge, and that turned out to be stand-up comedy. He loved having to think on his feet and found the laughter of strangers intoxicating.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: Once in a Lifetime by Talking Heads

Kirsty Young's castaway this week is the former Lord Chief Justice of England and Wales Lord Woolf. Throughout his career, he has been at the forefront of shaping our justice system. Following the Strangeways riots in 1990 he issued far-reaching reports on penal reform and his part in authorizing the release of James Bulger's killers attracted huge attention. As Master of the Rolls he made an historic judgement allowing Diane Blood to use her dead husband's sperm to have a child.

Lord Woolf's appetite to see justice done was sharpened as a wartime school boy and the only Jew at Fettes College in Edinburgh - he developed an early antipathy towards any perceived unfairness. His school master's contention that being a barrister wasn't the profession for a boy with a stutter only made him more determined to succeed.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: The Prisoner's Chorus from Fidelio by Ludwig van Beethoven

Kirsty Young's castaway this week is the composer Howard Goodall. He's a man of eclectic musical tastes and talents creating choral works, popular TV show themes like Black Adder and The Vicar of Dibley and movie scores and musicals. His enthusiasm and deep-rooted commitment to his life's work has regularly propelled him away from the score and onto our television screens where he's presented award winning documentaries like How Music Works. In January 2007 he was appointed as England's first ever National Ambassador for Singing, leading a £40 million scheme to improve group singing in primary schools.

Howard says he hears music in his head all the time - and can't imagine life without it.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: The first movement of Introitus from the Durufle Requiem by Maurice Durufle

Kirsty Young's castaway this week is the MP Diane Abbott. She was the first black woman to become a Member of Parliament and, after her election in 1987, she said she would find herself sitting on the green benches of the House of Commons wondering whether she was really entitled to be there.

It was not the first British institution she'd cracked - she had already propelled herself through Cambridge and then into the Civil Service. But she has not always sat comfortably inside these great bastions of the establishment; she says Gordon Brown booted her off an influential committee because she asked too many questions; she was a vocal opponent of the war in Iraq and she attracted a good deal of controversy when she decided to send her son to private school.

After more than 20 years in the House of Commons, she is, she says, happy for people to judge her on what she has done and what she has stood up for.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: Nkosi Sikelel 'Iafrika by Ladysmith Black Mambazo

Kirsty Young's castaway this week is one of our most successful singer-songwriters, Annie Lennox. Her extraordinary voice has captivated us for more than a quarter of a century and, as one half of the group Eurythmics and as a solo artist, she's sold tens of millions of records and won fistfuls of awards. As a teenager, her musical ability was her passport out of her home town of Aberdeen. At that point, a career as a flautist beckoned: but, after studying in London, she felt she could never make her mark as a classical musician. It was a chance encounter with aspiring pop-star Dave Stewart that set her on an entirely different path.

For much of the 1980s, all her creative energy went into making music. But when her children were born, she says, her priorities shifted. Now she devotes much of her time and energy to supporting different humanitarian causes. She says: "I need to find meaning in my life to make me happy; and that's been an ongoing struggle."

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: I Say A Little Prayer by Aretha Franklin

Kirsty Young's castaway this week is the actress Penelope Wilton. Her first love is the theatre and she's been highly acclaimed for her stage work in plays by Ibsen, Shaw, Shakespeare, Beckett - she relishes and shines in the difficult roles. Yet as one of our leading classical actresses she has no qualms about turning her talents to TV and film - Calendar Girls, Shaun of the Dead and Dr Who are among her more recent on screen appearances.

In-spite of being one of our best regarded actresses she is intensely private, intent upon disappearing into the lives of her characters. Penelope says that thing about being an actor is that you turn into other people, you have to hide yourself a bit in order to let that other person come out. People should see the character on the stage, not the actor.

Penelope grew up the middle of three girls and says that her mother was frail and often ill - she says this taught her to be self contained: "I was always worried that I would hurt her by taking a different view so one was sort of being terribly amenable - well of course that’s not in one's nature, I’m quite sharp and rather argumentative."

Favourite track: The 2nd movement of String Quintet in C Major by Franz Schubert

Kirsty Young's castaway this week is the cartoonist Mac. He's been the Daily Mail's cartoonist for the past 38 years - and it's his job, he says, to make the "dreary news copy of the daily paper brighter, by putting in a laugh". Since he was a child he was always drawing - inventing strip cartoons in his spare time and sketching figures in the margins of his school books. Yet despite his obvious talent, there was scant nurturing of his ambitions at home. His father told him he'd never make the grade and, instead, he should concentrate on finding a proper job.

But Mac says that all the way through, he's been lucky. Whenever he's found himself stuck, he's come across someone who would encourage him to take the next step. Life has, he says, been a series of lucky coincidences.

[Taken from the original programme material for this archive edition of Desert Island Discs]

Favourite track: The Adagio from Bruch's Violin Concerto in G Minor by Bruch