Dementia Matters

DNA Is Not Your Destiny: Genetics and Alzheimer’s Disease Risk


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This episode explores genetic risk factors for early- and late-onset Alzheimer’s disease. Host Nathaniel Chin and guest Corinne Engelman discuss the research looking into genetic risk for Alzheimer’s disease and the uncertainty that comes with genetic testing. Guest: Corinne Engelman, MSHP, PhD, associate professor, Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health

Episode Topics:

  • What are the genetic influences on a person’s risk for Alzheimer’s disease? 2:07
  • What genes affect individuals with early-onset dementia? 2:56
  • What is the impact of genes that counter one another? 5:34
  • How much can our lifestyle choices affect our genetic risk? 7:52
  • How is the genetic testing being analyzed? 9:03 
  • What can at-home genetic testing tell us about Alzheimer’s disease? 10:06
  • How essential is the role of genetic counselor? 11:47
  • Have we found any genetic risks related to the aging process? 13:21
  • What advice do you have for people interested in maximizing their genetic outcome when it comes to Alzheimer's disease risk? 14:40 
  • ...more
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    Dementia MattersBy Wisconsin Alzheimer‘s Disease Research Center

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