The smash hit TV show and video game ‘The Last of Us’ has spawned lots of curiosity about how worried we should be about the relatively unknown world of fungi. A figure in a recent BBC online article stated that fungal infections kill around 1.7 million people a year, about three times as many as malaria. In this episode we look at the both the global fight against malaria and David Denning, Professor of Infectious Diseases and Global Health at the University of Manchester explains the risks posed by fungal infections globally.