Dr Alo Show

Why did a cholesterol drug take a year and a half to start saving lives, and why did people without any visible plaque benefit just as much as those with confirmed disease?

Dr. Alo and Hannah break down the VESALIUS-CV mortality data, a rare cholesterol trial that measured actual deaths instead of just heart attacks and strokes, in people who had never had either. They cover the twenty percent drop in all-cause mortality, why the benefit only appeared after eighteen months, and what this means for anyone with plaque or high-risk diabetes still sitting on a borderline LDL.

https://dralo.net/links

Read the full post: https://dralo.net/blog/vesalius-repatha-all-cause-mortality

Questions this episode answers:
Why did the cholesterol drug take so long to reduce deaths?
What is the VESALIUS-CV trial and what did it find?
Does evolocumab reduce mortality in people without a prior heart attack?
Should I stop my cholesterol medication if I feel no difference?
What is apoB testing and why does it matter more than LDL?
Does PCSK9 inhibitor therapy help people with diabetes but no visible plaque?

Keywords: repatha, evolocumab, vesalius cv trial, pcsk9 inhibitor, ldl cholesterol, apob testing, cardiovascular mortality, atherosclerosis, statin therapy, heart attack prevention, cholesterol lowering drugs, primary prevention cardiology

This episode is for education only and is not medical advice. Talk to your own clinician about your own situation.

#heart #cardiology #drAlo #cholesterol #pcsk9 #ldl #heartdisease

A study of over 16,000 healthy adults with no history of heart disease used direct arterial imaging to check for plaque, and the results upend how doctors screen for risk.

Dr. Alo walks through the REACT study's findings on silent atherosclerosis by age and sex, why a zero calcium score can still hide dangerous plaque, and why standard risk calculators miss the vast majority of people who already have disease. You'll leave knowing which tests actually catch early plaque and why your thirties matter more than you think.

https://dralo.net/links

Read the full post: https://dralo.net/blog/atherosclerosis-healthy-adults-REACT

Questions this episode answers:
Can you have plaque in your arteries with no symptoms?
Does a zero calcium score mean my arteries are clean?
How accurate are heart disease risk calculators?
At what age does arterial plaque start forming?
What is the REACT study on atherosclerosis?
Should I get an apoB or Lipoprotein(a) test?

Keywords: arterial plaque, atherosclerosis, coronary calcium score, apob test, lipoprotein a, heart disease risk, react study, cardiovascular risk calculator, silent heart disease, carotid ultrasound, ldl cholesterol, early heart disease prevention

This episode is for education only and is not medical advice. Talk to your own clinician about your own situation.

#heart #cardiology #drAlo #atherosclerosis #heartdisease #apob #preventivehealth

Dr.

Alo digs into decades of fish oil trials, from early Japanese observations to VITAL, STRENGTH, and REDUCE-IT, to find out whether the supplement on your counter actually protects your heart. He breaks down why prescription EPA differs from over the counter capsules, exposes what independent testing found inside most supplement bottles, and shares exactly what he would do with his own lipid panel.

https://dralo.net/links

Read the full post: https://dralo.net/blog/fish

Questions this episode answers:
Does fish oil actually help your heart?
What did the reduce it trial really show?
Is prescription fish oil different from supplements?
Should I take fish oil for high triglycerides?
Does fish oil cause atrial fibrillation?
Is eating fish better than taking fish oil pills?

Keywords: fish oil heart health, omega 3 supplements, reduce it trial, epa and dha, prescription fish oil, vascepa, triglycerides treatment, statins and fish oil, fish oil supplement quality, cardiovascular risk reduction, lovaza, omega 3 clinical trials

This episode is for education only and is not medical advice. Talk to your own clinician about your own situation.

#heart #cardiology #drAlo #fishoil #omega3 #lipidology #hearthealth

Do seed oils like soybean oil actually raise inflammation, or is that just a social media myth?

This episode breaks down a new randomized controlled crossover trial from Ohio State University testing high dose soybean oil against palm oil in real people, walking through what happened to inflammatory markers, arachidonic acid, and oxidized LDL. You will also get the broader context of past studies, the study's limitations, and practical takeaways for what actually matters for your heart health.

https://dralo.net/links

Questions this episode answers:
Do seed oils cause inflammation?
Is soybean oil bad for you?
Does linoleic acid raise arachidonic acid?
What does the new seed oil study show?
Are vegetable oils bad for heart health?
Should I avoid soybean oil?

Keywords: seed oils, soybean oil, linoleic acid, inflammation study, arachidonic acid, oxidized ldl, omega 6 fats, heart disease risk, vegetable oil myth, randomized controlled trial, apob, nutrition science

This episode is for education only and is not medical advice. Talk to your own clinician about your own situation.

#heart #cardiology #drAlo #seedoils #linoleicacid #inflammation #hearthealth #nutritionscience

Your blood pressure reading at the doctor's office might be lying to you, in either direction.

Dr. Alo and Hannah break down white coat hypertension and masked hypertension, explaining the biology behind each, who is most at risk, and why one of them is far more dangerous than the other. You'll walk away with a simple seven day home monitoring protocol to find out which one actually applies to you.

https://dralo.net/links

Questions this episode answers:
Why is my blood pressure high at the doctor but normal at home?
What is white coat hypertension?
What is masked hypertension and is it dangerous?
How do I check my blood pressure at home correctly?
Do I need medication for white coat hypertension?
What is ambulatory blood pressure monitoring?

Keywords: white coat hypertension, masked hypertension, home blood pressure monitoring, ambulatory blood pressure monitoring, abpm, high blood pressure diagnosis, blood pressure medication, sustained hypertension, blood pressure at home, office blood pressure reading, hypertension risk, validated blood pressure monitor

This episode is for education only and is not medical advice. Talk to your own clinician about your own situation.

#heart #cardiology #drAlo #hypertension #bloodpressure #whitecoathypertension #heartdisease

Go beyond YouTube. Join My Heart 2 Heart VIP Inner Circle for weekly live Q&As + a private text line to Dr. Alo: https://dralo.net/community

Professor Alo breaks down the guidelines for those looking for a very in-depth guideline breakdown. Everything you need to understand the CAD, CCD, ASCVD treatment guidelines.

Go beyond YouTube. Join My Heart 2 Heart VIP Inner Circle for weekly live Q&As + a private text line to Dr. Alo: https://dralo.net/community

Professor Dr. Alo dives deep into the ASCVD Prevention Guidelines. How do we approach and prevent heart disease before it begins?

The American vs United Kingdom 2026 Diabetes treatment guidelines are out, and there are quite a few differences. Overview and comparison of the new 2026 American Diabetes Association Type 2 Diabetes Treatment Guidelines compared to the NICE Guidelines from the United Kingdom. Dr. Alo breaks down the differences and discusses his preferences. Also discuss case studies. Diabetes Grand Rounds.

Join My Heart 2 Heart VIP Inner Circle for weekly live Q&As + a private text line to Dr. Alo: https://dralo.net/community

The new 2026 Heart Failure Treatment Guidelines are out, and Dr. Alo, America's Cardiologist, dives very deep into the data and explains them. A deep dive into teh world of HFpEF, HFrEF, HFmrEF, ARNI, ARB, ACEi, SGLT2, GLP1, nsMRA, and MRA. Everything you need to know to treat heart failure correctly.

Join My Heart 2 Heart VIP Inner Circle for weekly live Q&As + a private text line to Dr. Alo: https://dralo.net/community

Cardiologist disagrees with the latest cholesterol treatment guidelines. Find out which parts he disagrees with and which parts he likes. The 2026 Dyslipidemia and Cholesterol Treatment Guidelines are a huge improvement, but could be even better.

https://dralo.net/links