Today we have episode 2 of our reproductive psychiatry series, and I will be talking about peri-partum psychiatric symptoms with a focus on depression. I will discuss all the factors surrounding treating these patients to include the use of medications. I will talk about the relative safety of the different antidepressants during pregnancy and give you my top choices for the safest ones. I will also talk about post-partum depression and two of the newest psychiatric medications which have recently been approved for this condition, Brexanolone (Zulresso) and Zuranolone (Zurzuvae).This is such a critical time in the life of mothers and growing fetuses. It is so important to treat psychiatric symptoms as it can have an impact for the rest of the child's life, so we want to make sure to treat and not treat at the right time and with the right medications. Suicide is also a leading cause of death during pregnancy and post-partum. So please have a listen!