In this week’s View, Dr. Eagle explores thirty-day outcomes of tricuspid edge-to-edge repair in clinical practice. He then discusses a study of the ISCHEMIA Trial, specifically the outcomes of patients who had complete revascularization versus those who did not. Finally, Dr. Eagle looks at decompression illness in divers with and without patent foramen ovale. 

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In this week’s View, Dr. Eagle explores a JACC State-of-the-Art Review of consumer wearable health and fitness technology and its role in cardiovascular medicine. He then discusses the 2023 update of the European Atherosclerosis Society’s consensus statement on homozygous familial hypercholesterolemia that offers new treatments and clinical guidance. Finally, Dr. Eagle looks at a recent post-hoc analysis of the SPRINT Trial on the effect of frailty on the efficacy and safety of intensive blood pressure control. 

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In this week’s View, Dr. Eagle explores a study on the effect of low-dose aspirin vs. placebo on the development of anemia. He then discusses the PARAGLIDE-HF study on the use of ARNI agents in patients with mildly reduced or preserved ejection fraction and worsening heart failure. Finally, Dr. Eagle looks at the very important study on the value of bempedoic acid in primary prevention for patients who are statin-intolerant. 

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In this week’s View, Dr. Eagle explores the long-term mortality of patients with Ebstein Anomaly. He then discusses a study that looks at the modifiability of cardiovascular risk associated with chronic kidney disease in patients with type 2 diabetes treated with finerenone. Finally, Dr. Eagle looks at the effect of SGLT2 inhibitors on cardiovascular outcomes across various patient populations. 

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In this week’s View, Dr. Eagle explores familial associations and prevalence of cause-specific mortality for thoracic aortic disease and bicuspid aortic valve disease. He then discusses a patient-level network meta-analyses from COMBINE that compares the use of direct-acting oral anticoagulants versus warfarin across the spectrum of kidney function. Finally, Dr. Eagle looks at biomarkers and cardiovascular outcomes in chimeric antigen receptor T-cell therapy recipients, as the field of cardio-oncology continues to evolve and grow. 

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In this week’s View, Dr. Eagle discusses one of the most important topics he has covered on the podcast this year: the proper measurement of blood pressure in the office and at home. He then explores the use of beta blockers in patients with stable ischemic heart disease. Finally, Dr. Eagle looks at PCI or CABG for left main coronary artery disease, as investigated in the SWEDEHEART registry. 

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In this week’s View, Dr. Eagle looks at SCORE2-Diabetes, a 10-year CV risk estimator for patients with type 2 diabetes. He then discusses the value of sex-specific stress perfusion cardiac MRI in suspected ischemic heart disease. Finally, Dr. Eagle explores a paper on managing patients with moderate aortic valve stenosis. 

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In this week’s View, Dr. Eagle looks at a pre-specified participant-level pooled analysis of PARAGLIDE-HF and PARAGON-HF that explores sacubitril/valsartan in heart failure with mildly reduced or preserved ejection fraction. He then covers the potential impact of pulmonary valve replacement in repaired tetralogy of Fallot. Finally, Dr. Eagle discusses a very large study on transcatheter mitral valve repair for degenerative mitral regurgitation. 

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In this week’s View, Dr. Eagle looks at a patient-level meta-analysis of the CHIEF-HF, DEFINE-HF, and PRESERVED-HF trials that investigated racial differences in quality of life for patients with heart failure treated with SGLT2 inhibitors. He then covers screening for dilated cardiomyopathy in at-risk first-degree relatives. Finally, Dr. Eagle discusses skeletal muscle mitochondrial respiration and exercise intolerance in patients with heart failure with preserved ejection fraction. 

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In this week’s View, Dr. Eagle looks at a comparison of apixaban vs warfarin in anticoagulating patients with an On-X mechanical aortic valve. He then covers the challenges and benefits we face in getting rapid, accurate publication and dissemination of clinical trial results. Finally, Dr. Eagle reviews an observational cohort study exploring the relationship between clinic and ambulatory blood pressure as it relates to cardiovascular outcomes. 

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