How much do we remember of what we learn in school or from conversation? Psychologist Adam Mastroianni says: from little to nothing much. What do our brains retain? Mastroianni argues that often it's a mix of emotions, meanings, and values that end up shaping who we are, what Mastroianni calls "vibes." Listen as he and EconTalk's Russ Roberts discuss the role of vibes in knowledge acquisition and the implications for how we teach, learn, and speak to those around us.

When then-hedge fund manager Elie Hassenfeld began his philanthropic journey in 2006, he knew that he wanted to get the most charitable bang for his buck. He quickly realized, however, that detailed data on charitable impact simply didn't exist. So he and Holden Karnovsky founded GiveWell, an organization inspired by effective altruism that identifies the charities that save or improve lives the most for every dollar given. Listen as Hassenfeld, GiveWell's CEO, explains to EconTalk's Russ Roberts how GiveWell determines the small number of charities they recommend to achieve optimal impact. They also discuss the dangers of an over-reliance on data and the case for bucketing our philanthropy to allow for local or personal giving.

We spend too much of our health care focus on lifespan and not enough on healthspan--the quality of our life as we get older. So argues Dr. Peter Attia, author of Outlive: The Science and Art of Longevity. Attia speaks with EconTalk's Russ Roberts about what kills us, what slows us down as we age, and the weapons we have to allow us to live better and longer.

In the original version of a now classic thought experiment, five people are about to be killed by a runaway trolley. Would you divert the trolley knowing that your choice will kill a single innocent bystander? Listen as Michael Munger of Duke University argues that Adam Smith gave an answer to this challenge a few hundred years before it was proposed by the philosopher Philippa Foot and brought vividly to life in the miniseries, The Good Place. Along the way, Munger and EconTalk's Russ Roberts discuss effective altruism, the moral claims of Peter Singer, what the trolley problem really tells us, if anything, and how our moral choices differ according to context.

Do marathons kill people who aren't in the race? Does when you're born make you more likely to get the flu? And what's the difference between a good doctor and a bad one? These are some of the questions Anupam Bapu Jena of Harvard University and EconTalk host Russ Roberts take up as they discuss Jena's book, Random Acts of Medicine.

Can economics and better measurement help us understand racial disparities and suggest how to reduce or eliminate them? Economist Roland Fryer of Harvard University believes deeply in the power of data to help us understand how the world works and how we might change it. Listen as he tells EconTalk's Russ Roberts of his devotion to this mission, what he learned from his grandmother, and what colleges can do if they really want to increase minority enrollment.

Early detection of cancer seems like a very good idea. But it's a lot more complicated than it seems. Oncologist and epidemiologist Vinay Prasad of the University of California, San Francisco talks to EconTalk's Russ Roberts about why many tests to detect cancer do little or nothing to extend lifespan.

Historian and author Walter Russell Mead of Bard College and the Hudson Institute talks with EconTalk's Russ Roberts about how innovation and religion can help us make sense of the current state of the world.

Psychologist and writer Adam Mastroianni says our minds are like the keep of a castle protecting our deepest held values and beliefs from even the most skilled attacks. The only problem with this design for self-preservation is that it also can keep out wisdom that might be both useful and true. Mastroianni's summary of the problem is "you can't reach the brain through the ears." Listen as Mastroianni talks with EconTalk's Russ Roberts about the implication of this view of mind for teaching, learning, and our daily interactions with the people around us.

The future of AI keeps Zvi Mowshowitz up at night. He also wonders why so many smart people seem to think that AI is more likely to save humanity than destroy it. Listen as Mowshowitz talks with EconTalk's Russ Roberts about the current state of AI, the pace of AI's development, and where--unless we take serious action--the technology is likely to end up (and that end is not pretty). They also discuss Mowshowitz's theory that the shallowness of the AI extinction-risk discourse results from the assumption that you have to be either pro-technological progress or against it.