Ellen Pompeo has spent 18 seasons playing Dr. Meredith Grey on Grey’s Anatomy—and it's fair to say doing something for that long can either make or break your creativity. For Ellen, it’s been a task of finding new ways to keep Grey’s relevant to audiences, as well as exploring new ventures outside of acting such as her new podcast Tell Me. In our conversation, Ellen explains how she keeps her creativity fresh, her struggles with being a perfectionist, and with maybe being a little bit too outspoken at times.