<a target="_blank" href="https://www.buzzsprout.com/1535644/fan_mail/new">Send us Fan Mail</a>Nick talks to Dr. Matthew Hill about the role of the endocannabinoid system in regulating stress and emotional behavior. They also discuss how plant cannabinoids from Cannabis, such as THC and CBD, impact the endocannabinoid system.  *Not medical advice. <a rel="payment" href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter">Support the show</a>Health Products by M&M Partners:<ul><li><a href='https://aquatruwater.com/?oid2=50&affid2=11307'>AquaTru</a>: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.</li><li><a href='https://omegaquant.com/ref/1005'>OmegaQuant</a>: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.</li><li><a href='https://siphoxhealth.com/trikomes'>SiPhox Health</a>: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.</li><li><a href='https://santabarbaranutrients.com/products/ketocitra'>KetoCitra</a>—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)</li><li><a href='https://sporesmd.com/?ref=mindmatter'>SporesMD</a>: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.</li></ul>For all the ways you can <a href='https://mindandmatter.substack.com/p/how-to-support-mind-and-matter'>support my efforts</a>

Send us Fan Mail Nick talks to Dr. Matthew Hill about the role of the endocannabinoid system in regulating stress and emotional behavior. They also discuss how plant cannabinoids from Cannabis, such as THC and CBD, impact the endocannabinoid system. *Not medical advice. Support the show Health Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts

<a href="https://www.buzzsprout.com/1535644/fan_mail/new" rel="noopener noreferrer">Send us Fan Mail</a>Nick talks to Dr. Matthew Hill about the role of the endocannabinoid system in regulating stress and emotional behavior. They also discuss how plant cannabinoids from Cannabis, such as THC and CBD, impact the endocannabinoid system.&nbsp; *Not medical advice. <a href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter" rel="noopener noreferrer">Support the show</a>Health Products by M&amp;M Partners:<ul><li><a href="https://aquatruwater.com/?oid2=50&amp;affid2=11307" rel="noopener noreferrer">AquaTru</a>: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic &amp; Under Sink Units; $300 off Freestanding models.</li><li><a href="https://omegaquant.com/ref/1005" rel="noopener noreferrer">OmegaQuant</a>: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&amp;M.</li><li><a href="https://siphoxhealth.com/trikomes" rel="noopener noreferrer">SiPhox Health</a>: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.</li><li><a href="https://santabarbaranutrients.com/products/ketocitra" rel="noopener noreferrer">KetoCitra</a>—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)</li><li><a href="https://sporesmd.com/?ref=mindmatter" rel="noopener noreferrer">SporesMD</a>: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.</li></ul>For all the ways you can <a href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter" rel="noopener noreferrer">support my efforts</a>

Endocannabinoid System, Stress & PTSD | Matthew Hill | 11

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists &amp; thinkers alive today about how your mind-body reacts to what you feed it. The weekly <a href="https://mindandmatter.substack.com/podcast?sort=top">M&amp;M podcast</a> features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&amp;M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body &amp; mind work by curating &amp; synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: <ul><li><a href="https://mindandmatter.substack.com/p/the-psychiatry-of-metabolism">Taking ownership of your health starts with taking ownership of your information diet</a>.</li><li>All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas &amp; preferred conclusions.</li><li>Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but <a href="https://mindandmatter.substack.com/p/what-is-psychological-dissociation-78d">pain is information.</a></li></ul> Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload &amp; historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: <ul><li>“Γνῶθι σεαυτόν” (Know thyself)</li><li>“Μηδὲν ἄγαν” (Nothing in excess)</li><li>“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)</li></ul>

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Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet.All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” (Know thyself)“Μηδὲν ἄγαν” (Nothing in excess)“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists &amp; thinkers alive today about how your mind-body reacts to what you feed it. The weekly <a href="https://mindandmatter.substack.com/podcast?sort=top" rel="noopener noreferrer">M&amp;M podcast</a> features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&amp;M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body &amp; mind work by curating &amp; synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: <ul><li><a href="https://mindandmatter.substack.com/p/the-psychiatry-of-metabolism" rel="noopener noreferrer">Taking ownership of your health starts with taking ownership of your information diet</a>.</li><li>All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas &amp; preferred conclusions.</li><li>Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but <a href="https://mindandmatter.substack.com/p/what-is-psychological-dissociation-78d" rel="noopener noreferrer">pain is information.</a></li></ul> Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload &amp; historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: <ul><li>“Γνῶθι σεαυτόν” (Know thyself)</li><li>“Μηδὲν ἄγαν” (Nothing in excess)</li><li>“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)</li></ul>

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Endocannabinoid System, Stress & PTSD | Matthew Hill | 11

Endocannabinoid System, Stress & PTSD | Matthew Hill | 11

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