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“What if your body isn’t failing you… but asking for a different kind of support?”
In this episode, Dr. Mariza sits down with Mickey Trescott to unpack the powerful connection between inflammation, autoimmune disease, gut health, and perimenopause.
Together, they explore why so many women are dismissed when labs look “normal” despite debilitating symptoms like fatigue, bloating, brain fog, joint pain, skin issues, and weight resistance. Mickey shares her personal journey with Hashimoto’s, celiac disease, and autoimmune recovery—and how the Autoimmune Protocol (AIP) became a transformative tool for reducing inflammation and helping millions feel better in their bodies.
They also dive into the evolution of AIP over the last 15 years, the newest research validating its effectiveness, and why perimenopause often becomes an inflammatory inflection point where hidden symptoms suddenly rise to the surface.
If you’ve been struggling with chronic inflammation, unexplained symptoms, or feeling dismissed by conventional medicine, this conversation will help you connect the dots—and give you practical hope moving forward.
MICKEY TRESCOTT
Mickey Trescott is a nutritional therapy practitioner, cookbook author, and co-creator of the Autoimmune Protocol (AIP). After being diagnosed with Hashimoto’s thyroiditis and celiac disease in her twenties, she dedicated her work to helping people navigate autoimmune disease through nutrition, lifestyle medicine, and inflammation support. She has helped shape the modern AIP movement and trained hundreds of healthcare practitioners around the world.
IN THIS EPISODE
QUOTES
“Your body is not working against you. It’s asking for a different level of support.”
“Three out of every four-ish people get clinical improvement from doing an elimination diet when you have autoimmune disease.”
“When hormones begin to shift, the body becomes far less tolerant of underlying inflammation.”
RESOURCES MENTIONED
Order my new book: The Perimenopause Revolution
https://peri-revolution.com/
Use code ENERGIZED and get 30% off on your first BATCH order
http://hellobatch.com/ENERGIZED
Grab Mickey’s new AIP book
https://theautoimmuneprotocol.com/
Visit Autoimmune Wellness Website
Autoimmune Wellness Instagram
Mickey Trescott Instagram
Mickey Trescott Facebook
Mickey Trescott Youtube
RELATED EPISODES
747: The Silent Shift: Why Perimenopause Changes Everything
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
741: Estrogen, Gut Health, and Metabolism with Siobhan Mitchell
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
“Perimenopause is more than just hot flashes and mood swings—it’s a biological inflection point.”
In this solo episode, Dr. Mariza discusses the deeper, often overlooked changes happening during perimenopause and menopause. It’s more than a reproductive shift; it’s a systemic change affecting the brain, metabolism, hormones, mitochondria, gut health, and more.
Dr. Mariza delves into the silent shift that many women experience—feeling exhausted, stressed, and unproductive despite their best efforts. She explains how perimenopause accelerates aging processes, and why early intervention is key to reducing long-term health risks and preserving vitality.
This episode focuses on actionable steps you can take to support your body during this critical transition—from stabilizing blood sugar and building muscle to optimizing sleep and protecting your brain.
If you’ve been feeling “off” but can’t explain why, this episode is a must-listen.
Be sure to tune in!
IN THIS EPISODE
QUOTES
“Perimenopause is more than just skipped periods or hot flashes. It’s a shift in every system of the body.”
“You deserve so much better than being told to just survive this season.”
“The moment to intervene is now—not when your health has deteriorated.”
RESOURCES MENTIONED
Order my newest book: The Perimenopause Revolution
https://peri-revolution.com/
Use code ENERGIZED and get 10% off on your Troscription Order
http://troscriptions.com/ENERGIZED
Use code DRMARIZA and get 10% off on your Womeness Order
https://www.womaness.com/DRMARIZA
Check out the Morning Metabolic Ignition Method for better energy and resilience
RELATED EPISODES
744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
741: Estrogen, Gut Health, Mitochondria, and Cardiovascular Health: What Changes In Perimenopause with Dr. Siobhan Mitchel
“Is your nervous system stuck in overdrive?”
In this episode, Dr. Mariza sits down with Jenna Free, a counselor specializing in ADHD and nervous system regulation, to discuss why so many women in midlife feel overwhelmed, scattered, and exhausted despite their best efforts to stay organized.
Together, they explore how the nervous system gets stuck in a chronic fight-or-flight state, the role of dysregulation in ADHD symptoms, and why traditional productivity hacks simply don’t work when your nervous system is running on empty.
Jenna breaks down her approach to resetting the nervous system and explains how small, consistent changes can lead to massive improvements in mental clarity, energy, and overall well-being.
This conversation offers new insights on how to break free from the cycle of rushing, crashing, and feeling burned out—and provides tangible steps to reclaim control over your brain and nervous system.
JENNA FREE
Jenna Free is a counselor specializing in ADHD, nervous system regulation, and mindfulness practices. She is passionate about helping women overcome the chaos of constant overwhelm and hypervigilance by teaching them how to regulate their nervous systems and achieve sustainable productivity. Jenna is the author of The Simple Guide to ADHD Regulation and offers support to those struggling with ADHD and chronic stress
IN THIS EPISODE
QUOTES
“Being in survival mode is a primal mechanism, but it’s not meant to be how we live in 2026.”
“If you believe that being frantic and rushed is the way to be successful, you will never change.”
“Regulation work isn’t about feeling nice—it’s about functioning better.”
RESOURCES MENTIONED
Use code ENERGIZED and get 10% off on your MitoQ Order
https://www.mitoq.com/energized
Order The Simple Guide to ADHD Regulation
https://www.jennafree.com/book
Order my newest book: The Perimenopause RevolutionJenna Free
https://peri-revolution.com/
Jenna Free Website
https://www.jennafree.com/
Jenna Free Instagram
Jenna Free Youtube
RELATED EPISODES
744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
693: Tired All the Time? It Might Be Hidden Problems With Your Mitochondria with Siobhan Mitchell
Why are so many women waking up exhausted… but unable to shut their brain off?”
In this episode, Dr. Mariza sits down with Scott Sherr to unpack the hidden nervous system and biochemical shifts driving sleep struggles, anxiety, exhaustion, and feeling “wired and tired” in midlife.
Together, they explore why women in perimenopause often lose stress resilience, why the brain gets stuck in overdrive at night, and how neurotransmitters like GABA, serotonin, adenosine, and cortisol shape sleep quality, recovery, and mood.
They also dive into the powerful connection between mitochondrial health, nervous system regulation, energy production, and why building more “reserve” may be the missing key to feeling calm, focused, and resilient again.
If you’ve been struggling with middle-of-the-night wakeups, burnout, anxiety, or feeling like your brain never truly powers down, this episode will help connect the dots—and offer practical solutions that actually move the needle.
Dr. Scott Sherr
Dr. Scott Sherr is a physician, health optimization expert, and Chief Operating Officer of Troscriptions. His work focuses on nervous system regulation, mitochondrial health, hyperbaric medicine, sleep optimization, and performance medicine. He is passionate about helping people improve resilience, energy, recovery, and cognitive performance through science-backed strategies and targeted support.
IN THIS EPISODE
QUOTES
“Sleep will make or break you the next day—especially in this season of life.”
“To increase your performance is having more reserve.”
“You’re not meant to live in a state of disruption, exhaustion, and feeling wired and tired all the time.”
RESOURCES MENTIONED
Use code ENERGIZED and get 10% off on your Troscription Order
http://troscriptions.com/ENERGIZED
Use code ENERGIZED and get 10% off on your MitoQ Order
https://www.mitoq.com/energized%C2%A0
Troscriptions Website
Dr. Scott Sherr Instagram
Dr. Scott Sherr Youtube
RELATED EPISODES
744: The Midlife Brain Reset: How to Protect Your Memory, Focus & Mental Sharpness Starting Now
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
593: Why EVERYONE Needs Progesterone in Perimenopause & Beyond with Carol Petersen
“Is this brain fog… or something more?”
In this solo episode, Dr. Mariza unpacks the hidden neurological and metabolic shifts happening during perimenopause and menopause—and why so many women suddenly feel mentally “off.”
From brain fog and memory lapses to anxiety, overwhelm, and lower stress resilience, these symptoms are often dismissed as aging or stress. But Dr. Mariza explains that this is actually a neuroendocrine and metabolic transition driven by changing hormones, brain energy shifts, inflammation, and blood sugar instability.
She breaks down what’s really happening inside the female brain during midlife, why women feel more sensitive to stress, and the most powerful lifestyle strategies to support long-term brain health, energy, mood, and resilience.
If you’ve been wondering why you don’t quite feel like yourself anymore, this episode will help connect the dots—and give you a roadmap forward.
IN THIS EPISODE
QUOTES
“Stabilizing your blood sugar is the fastest way to reclaim your energy, your focus, and your calm.”
“What we’re dealing with is an energy problem—and once you see it that way, everything changes.”
“Your brain is not broken. It is adapting and recalibrating.”
RESOURCES MENTIONED
Order my new book: The Perimenopause Revolution
https://peri-revolution.com/
Learn more about Joi & Blokes
https://joiandblokes.com/labs-with-dr-mariza-snyder/
Explore Berkeley Life Nitric Oxide Support
https://berkeleylife.pxf.io/Vxvdja
Download the Midlife Lab Guide
https://dmdl.s3.amazonaws.com/Dr-Mariza_Hormone-Lab-Testing-Checklist-%26-Reference-Guide.pdf
RELATED EPISODES
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
743: Why Your Heart Risk Changes in Menopause with Dr. Jayne Morgan
693: Tired All the Time? It Might Be Hidden Problems With Your Mitochondria with Siobhan Mitchell
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
“Why is heart disease still the #1 killer of women—and why aren’t we talking about it?”
In this episode, Dr. Mariza sits down with Jayne Morgan to unpack the overlooked connection between perimenopause, menopause, and cardiovascular risk.
Most women are told menopause is just about hormones and symptoms—but it’s actually a vascular transition that directly impacts your heart, blood vessels, and long-term health.
Together, they break down why women are often misdiagnosed, why key risk markers are missed, and what you can do to advocate for yourself early—before a major event happens.
If you’re in your 40s or beyond, this conversation could change how you think about your health—and your future.
Be sure to tune in!
DR. JAYNE MORGAN
Dr. Jayne Morgan is a leading cardiologist and national voice in women’s cardiovascular health. She is passionate about redefining “preventive care” for women—shifting the focus from reproductive health alone to include heart health, vascular function, and long-term longevity.
IN THIS EPISODE
QUOTES
“Real preventive medicine for women is preventive cardiovascular medicine.”
“Menopause is not just a hormonal transition—it’s a vascular one.”
“If you don’t measure it, you can’t manage it.”
RESOURCES MENTIONED
Order my newest book: The Perimenopause Revolution
https://peri-revolution.com/
Dr. Jayne Morgan Instagram
Dr. Jayne Morgan Youtube
RELATED EPISODES
723: Estrogen, Insulin & Heart Disease: Why Your Risk Rises in Midlife
711: Estrogen, Inflammation, and Your Heart Health: What Every Woman Needs to Know with Dr. Sanjay Bhojra
675: Feeling Off After 40? The Surprising Vitality Molecule to Reignite Your Energy, Libido & Confidence with Cathy Eason
741: Estrogen, Gut Health, and Metabolism with Siobhan Mitchell
In today’s episode, we’re talking about the very real mental energy drain that so many midlife women are experiencing—and how it can quietly lead to career burnout.
From mood swings, irritation, and resentment to brain fog and forgetfulness in high-stakes moments, these changes can leave you feeling like you’re not yourself anymore.
But here’s the truth: this is not a willpower problem or a personal failure— it’s a biological shift happening during perimenopause with very real professional consequences.
This episode is a call to stop suffering in silence and start advocating for better support, awareness, and care for women in this phase of life.
If you’re ready to reclaim your clarity and confidence— and step fully into your most powerful chapter—this conversation is for you.
Tune in here!
IN THIS EPISODE
QUOTES
“That brilliant brain of yours is suddenly running on 25% to 30% less energy because that’s what's going on in perimenopause.”
“65% to 99% of women say their symptoms negatively affected their work performance, with brain fog being the biggest culprit in terms of focus, clarity, alertness, and mental bandwidth. More than half of women make career-limiting decisions during perimenopause.”
“It's about you going through a profound biological transition in your life that deserves support, understanding, and solutions that actually work.”
RESOURCES MENTIONED
Join my Midlife on Fire Collective HERE!
Order my newest book: The Perimenopause Revolution HERE!
RELATED EPISODES
728: WHY BRAIN FOG ISN’T RANDOM: THE HORMONE SHIFT BEHIND IT
721: No, It’s Not All in Your Head: The Medical Truth About Perimenopause with Dr. Jila Senemar
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
690: The Perimenopause Revolution: Why midlife isn’t the end — it’s the beginning of your most energized, powerful, and vibrant self
“Why does your body stop responding… even when you’re doing everything right?”
In this episode, Dr. Mariza sits down with Siobhan Mitchell to unpack the true metabolic and cellular shifts happening in perimenopause and menopause.
So many women feel like their body has suddenly turned against them—weight gain, fatigue, brain fog, and rising inflammation—despite doing all the right things. But this isn’t a failure of effort. It’s a biological inflection point driven by declining estrogen and its impact on metabolism, mitochondria, and vascular health.
Together, they break down how estrogen loss reshapes everything from blood sugar control to fat storage, mitochondrial function, and long-term cardiovascular risk—while also exploring the emerging role of gut health and phytoestrogens like S-equol as targeted support.
If you’ve been working harder than ever with fewer results, this episode will help you understand why—and what to do instead.
Be sure to tune in!
SIOBHAN MITCHEL
Dr. Siobhan Mitchel, PhD, is a neuroscientist and Chief Scientific Officer at MitoQ. Her work focuses on mitochondrial health, cellular energy, and the role of oxidative stress in aging—particularly in women navigating perimenopause and menopause. She is passionate about advancing research that supports women’s long-term health, metabolism, and resilience at the cellular level.
IN THIS EPISODE
Why your body stops responding the same way in perimenopause
How estrogen loss impacts metabolism, fat storage, and blood sugar
The role of mitochondria in energy, brain function, and weight changes
Why visceral belly fat increases—and why it’s more dangerous
The connection between gut health, estrogen metabolism, and inflammation
How phytoestrogens (like S-equol) support metabolism and hormone signaling
Why midlife is a metabolic and vascular inflection point—not just hormonal
QUOTES
“This isn’t a failure of effort—it’s a biological shift happening beneath the surface.”
“When estrogen declines, you don’t just lose hormones—you lose metabolic protection.”
“If you support your mitochondria, you support your energy, your metabolism, and your long-term health.”
RESOURCES MENTIONED
Order my new book: The Perimenopause Revolution HERE!
https://peri-revolution.com/
Use code ENERGIZED and get 10% off MitoQ
http://www.mitoq.com/energized
MitoQ Instagram
MitoQ Facebook
MitoQ Youtube
RELATED EPISODES
693: The Cellular Shift in Perimenopause: Mitochondria, Metabolism, and Energy
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
705: The Metabolic Shift No One Warned You About in Midlife
“Is it really just hormones… or is your gut driving the symptoms?”
In this episode, Dr. Mariza sits down with Cynthia Thurlow to unpack the powerful connection between gut health and hormones in midlife.
Many women are told their bloating, weight gain, fatigue, and mood shifts are “just hormones.” But Cynthia explains that the gut microbiome plays a central role in how these symptoms show up—and how they can be improved.
Together, they break down how gut health influences hormones, inflammation, metabolism, and brain function, while also highlighting the foundational habits that matter most in this season.
If you’ve been feeling off and unsure where to focus, this episode will give you clarity and a smarter path forward.
Be sure to tune in!
CYNTHIA THURLOW
Cynthia Thurlow is a nurse practitioner, intermittent fasting expert, and leading voice in metabolic health for women in midlife. With a background in cardiology, she now focuses on helping women navigate perimenopause and menopause through personalized nutrition, gut health, and lifestyle strategies. She is the author of The Menopause Gut and a passionate advocate for empowering women to take control of their health during this pivotal transition.
IN THIS EPISODE
QUOTES
“Midlife isn’t just a hormonal shift—it’s a metabolic and microbial shift happening beneath the surface.”
“When you support your gut, you’re not just improving digestion—you’re impacting your hormones, your brain, and your long-term resilience.”
“This phase of life is an invitation to set boundaries, prioritize your needs, and finally major in what matters most.”
RESOURCES MENTIONED
👉🏻 Order my new book: The Perimenopause Revolution HERE!
⛓️💥 https://peri-revolution.com/
👉🏻 Order Cynthia’s book: The Menopause Gut
⛓️💥 https://amzn.to/4eoEIsX
👉🏻 Use code ENERGIZED and get 10% off on your Troscription Order
⛓️💥 http://troscriptions.com/ENERGIZED
Cynthia Thurlow’s Website
Cynthia Thurlow on Instagram
RELATED EPISODES
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
701: The Gut–Hormone Connection: Why Your Symptoms Aren’t Just Hormones
689: Blood Sugar, Inflammation, and the Midlife Metabolism Shift
“Is this brain fog… or something more?”
In this episode, brain expert Dr. Majid Fotuhi explains how perimenopause is a true neuroendocrine transition, where shifting hormones can temporarily impact memory, focus, sleep, and mood—often leaving women worried they’re experiencing early cognitive decline.
The good news? These changes are typically transient, and as hormones stabilize, the brain can return to its baseline function.
Dr. Fotuhi shares that what many women are experiencing is not the beginning of the end, but a normal phase—and one that can be supported with the right lifestyle and brain-health strategies.
If you’ve been feeling “off” mentally and wondering what it means for your future, this episode will bring you the peace of mind you need.
Be sure to tune in!
Majid Fotuhi
Dr. Majid Fotuhi serves as an adjunct professor at the Mind/Brain Institute at Johns Hopkins University and teaches at George Washington University and Harvard Medical School. With 37 years of experience in teaching, clinical practice, and neuroscience research, Dr. Fotuhi has pioneered a multidisciplinary approach to enhancing brain vitality and cognitive performance at any age. His groundbreaking “Brain Fitness Program” combines a comprehensive baseline “Brain Portfolio” assessment with 12 bi-weekly brain training sessions. He’s the author of three books and is recognized as one of the leading experts in memory and successful aging.
IN THIS EPISODE
QUOTES
“Exercise is the only intervention that has been shown to increase the number of cells in the hippocampus, which is a memory part of the brain. No other intervention increases the number of brain cells… exercise is the fountain of youth, the miracle cure for so many problems, psychological, physical, and it's a no-brainer.”
“Lifestyle choices and how you live your day, hour to hour, make a difference in what your brain would look like in the future. And if you do a lot of good things in a short period of time, you can see significant improvements.”
“84% of our patients had objective improvements in the cognitive test, but pretty much a hundred percent improved in some ways. They felt better, they slept better, they had more energy, they had a better positive outlook toward the future. Everybody improved.”
RESOURCES MENTIONED
👉🏻 Order my new book: The Perimenopause Revolution
⛓️💥 https://peri-revolution.com/
👉🏻 Order Dr. Fotuhi’s latest book: The Invincible Brain
⛓️💥https://amzn.to/4cuqvIj
Dr. Fotuhi’s Website
Dr. Fotuhi on Instagram
RELATED EPISODES
728: Why Brain Fog Isn’t Random: The Hormone Shift Behind It
667: The Hidden Foods and Habits Fueling Brain Inflammation And How to Reverse It Naturally with Dr. Austin Perlmutter
668: Your Brain on Perimenopause: The Hidden Neurological Transition No One Warns You About
717: “I Don’t Feel Like Myself Anymore”: The Mental & Emotional Reality of Perimenopause
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